The Drosophila CD36 Homologue croquemort Is Required to Maintain Immune and Gut Homeostasis during Development and Aging

Corpse Engulfment Generates a Molecular Memory that Primes the Macrophage Inflammatory Response

(2016) Helen Weavers et al.   CELL

Preventing Age-Related Decline of Gut Compartmentalization Limits Microbiota Dysbiosis and Extends Lifespan

(2016) Hongjie Li et al.   Cell Host & Microbe

How Many Parameters Does It Take to Describe Disease Tolerance?

(2016) Alexander Louie et al.   PLOS BIOLOGY

Remote Control of Intestinal Stem Cell Activity by Haemocytes in Drosophila

(2016) Sveta Chakrabarti et al.   PLoS Genetics

Active Hematopoietic Hubs in Drosophila Adults Generate Hemocytes and Contribute to Immune Response

(2015) Saikat Ghosh et al.   DEVELOPMENTAL CELL

Macrophage-Derived upd3 Cytokine Causes Impaired Glucose Homeostasis and Reduced Lifespan in Drosophila Fed a Lipid-Rich Diet

(2015) Katie J. Woodcock et al.   IMMUNITY

Haemocytes control stem cell activity in the Drosophila intestine

(2015) Arshad Ayyaz et al.   NATURE CELL BIOLOGY

Macrophages and cellular immunity in Drosophila melanogaster

(2015) Katrina S. Gold et al.   SEMINARS IN IMMUNOLOGY

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

(2015) Rebecca I. Clark et al.   Cell Reports

Drosophila sessile hemocyte clusters are true hematopoietic tissues that regulate larval blood cell differentiation

(2015) Alexandre B Leitão et al.   eLife

The Nimrod transmembrane receptor Eater is required for hemocyte attachment to the sessile compartment in Drosophila melanogaster

(2015) A. J. Bretscher et al.   Biology Open

Apoptosis in Hemocytes Induces a Shift in Effector Mechanisms in the Drosophila Immune System and Leads to a Pro-Inflammatory State

(2015) Badrul Arefin et al.   PLoS One

PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan

(2014) Linlin Guo et al.   CELL

The intersection of immune deficiency and autoimmunity

(2014) Solrun M. Maggadottir et al.   CURRENT OPINION IN RHEUMATOLOGY

The Nonaspanins TM9SF2 and TM9SF4 Regulate the Plasma Membrane Localization and Signalling Activity of the Peptidoglycan Recognition Protein PGRP-LC in Drosophila

(2014) Jackie Perrin et al.   Journal of Innate Immunity

Epidermal Cells Are the Primary Phagocytes in the Fragmentation and Clearance of Degenerating Dendrites in Drosophila

(2014) Chun Han et al.   NEURON

Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology

(2014) N. A. Broderick et al.   mBio

Impact of Microbes on Autoimmune Diseases

(2013) Claudia Danzer et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Resolution of inflammation: an integrated view

(2013) Almudena Ortega-Gómez et al.   EMBO Molecular Medicine

The Scavenger Receptor CD36 Downmodulates the Early Inflammatory Response while Enhancing Bacterial Phagocytosis during Pneumococcal Pneumonia

(2013) O. Sharif et al.   JOURNAL OF IMMUNOLOGY

CD36 Contributes to Malaria Parasite-Induced Pro-Inflammatory Cytokine Production and NK and T Cell Activation by Dendritic Cells

(2013) Nagaraj M. Gowda et al.   PLoS One

Steroid Hormone Signaling Is Essential to Regulate Innate Immune Cells and Fight Bacterial Infection in Drosophila

(2013) Jennifer C. Regan et al.   PLoS Pathogens

Phagocytosis of bacterial pathogens

(2012) Yoon-Suk Alexander Chung et al.   FLY

Independent Recognition ofStaphylococcus aureusby Two Receptors for Phagocytosis inDrosophila

(2012) Akiko Shiratsuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Real-Time Analysis of Drosophila Post-Embryonic Haemocyte Behaviour

(2012) Christopher J. Sampson et al.   PLoS One

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila

(2012) M. Rera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease Tolerance as a Defense Strategy

(2012) R. Medzhitov et al.   SCIENCE

A novel tissue in an established model system: the Drosophila pupal midgut

(2011) Shigeo Takashima et al.   DEVELOPMENT GENES AND EVOLUTION

Low-diversity bacterial community in the gut of the fruitfly Drosophila melanogaster

(2011) Chun Nin Adam Wong et al.   ENVIRONMENTAL MICROBIOLOGY

Senescence of the cellular immune response in Drosophila melanogaster

(2011) Danielle K. Mackenzie et al.   EXPERIMENTAL GERONTOLOGY

The resolution of inflammation: the devil in the flask and in the details

(2011) Charles N. Serhan   FASEB JOURNAL

Transcriptional regulation of eater gene expression in Drosophila blood cells

(2011) Paul T. Kroeger et al.   GENESIS

Negative Regulation by Amidase PGRPs Shapes the Drosophila Antibacterial Response and Protects the Fly from Innocuous Infection

(2011) Juan C. Paredes et al.   IMMUNITY

Relative Roles of the Cellular and Humoral Responses in the Drosophila Host Defense against Three Gram-Positive Bacterial Infections

(2011) Nadine T. Nehme et al.   PLoS One

Wall Teichoic Acids of Staphylococcus aureus Limit Recognition by the Drosophila Peptidoglycan Recognition Protein-SA to Promote Pathogenicity

(2011) Magda L. Atilano et al.   PLoS Pathogens

Crohn’s disease as an immunodeficiency

(2010) Bu’Hussain Hayee et al.   Expert Review of Clinical Immunology

Ontogeny of the Drosophila larval hematopoietic organ, hemocyte homeostasis and the dedicated cellular immune response to parasitism

(2010) Joanna Krzemien et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Inflammation, atherosclerosis, and arterial thrombosis: Role of the scavenger receptor CD36

(2009) R. L. SILVERSTEIN   CLEVELAND CLINIC JOURNAL OF MEDICINE

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

(2009) N. Buchon et al.   GENES & DEVELOPMENT

In vivo detection of lamellocytes in Drosophila melanogaster

(2009) Viktor Honti et al.   IMMUNOLOGY LETTERS

Genetic Ablation of Drosophila Phagocytes Reveals Their Contribution to Both Development and Resistance to Bacterial Infection

(2009) Arnaud Defaye et al.   Journal of Innate Immunity

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response

(2009) B. Charroux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Six-Microns-Under Acts Upstream of Draper in the Glial Phagocytosis of Apoptotic Neurons

(2008) Estee Kurant et al.   CELL

JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut

(2008) Benoît Biteau et al.   Cell Stem Cell

Antimicrobial Defense and Persistent Infection in Insects

(2008) E. R. Haine et al.   SCIENCE

Phagocytic Receptor CED-1 Initiates a Signaling Pathway for Degrading Engulfed Apoptotic Cells

(2008) Xiaomeng Yu et al.   PLOS BIOLOGY

A Signaling Protease Required for Melanization in Drosophila Affects Resistance and Tolerance of Infections

(2008) Janelle S Ayres et al.   PLOS BIOLOGY