Yeast as a Heterologous Model System to Uncover Type III Effector Function

Yeast Proteome Dynamics from Single Cell Imaging and Automated Analysis

(2015) Yolanda T. Chong et al.   CELL

Subversion of the cytoskeleton by intracellular bacteria: lessons fromListeria,SalmonellaandVibrio

(2015) Marcela de Souza Santos et al.   CELLULAR MICROBIOLOGY

Unbiased Proteomic Profiling Strategy for Discovery of Bacterial Effector Proteins Reveals that Salmonella Protein PheA Is a Host Cell Cycle Regulator

(2015) Ha-Na Na et al.   CHEMISTRY & BIOLOGY

From equator to pole: splitting chromosomes in mitosis and meiosis

(2015) Eris Duro et al.   GENES & DEVELOPMENT

The AvrE superfamily: ancestral type III effectors involved in suppression of pathogen-associated molecular pattern-triggered immunity

(2015) Alexandre Degrave et al.   MOLECULAR PLANT PATHOLOGY

CYCLoPs: A Comprehensive Database Constructed from Automated Analysis of Protein Abundance and Subcellular Localization Patterns in Saccharomyces cerevisiae

(2015) J. L. Y. Koh et al.   G3-Genes Genomes Genetics

Bacterial Pathogen Manipulation of Host Membrane Trafficking

(2014) Seblewongel Asrat et al.   Annual Review of Cell and Developmental Biology

Bacterial Type III Secretion Systems: Specialized Nanomachines for Protein Delivery into Target Cells

(2014) Jorge E. Galán et al.   Annual Review of Microbiology

Budding Yeast for Budding Geneticists: A Primer on the Saccharomyces cerevisiae Model System

(2014) Andrea A. Duina et al.   GENETICS

The Yeast Deletion Collection: A Decade of Functional Genomics

(2014) Guri Giaever et al.   GENETICS

Expression of the Bacterial Type III Effector DspA/E inSaccharomyces cerevisiaeDown-regulates the Sphingolipid Biosynthetic Pathway Leading to Growth Arrest

(2014) Sabrina Siamer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

I’m coming to GEF you: Regulation of RhoGEFs during cell migration

(2014) Silvia M Goicoechea et al.   Cell Adhesion & Migration

Rho family GTPase-dependent immunity in plants and animals

(2014) Yoji Kawano et al.   Frontiers in Plant Science

Hijacking of Rho GTPases during bacterial infection

(2013) Emmanuel Lemichez et al.   EXPERIMENTAL CELL RESEARCH

Exoenzyme S ADP-Ribosylates Rab5 Effector Sites To Uncouple Intracellular Trafficking

(2013) Nathan C. Simon et al.   INFECTION AND IMMUNITY

Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ

(2013) Nikolay Burnaevskiy et al.   NATURE

Functional genomics in the study of yeast cell polarity: moving in the right direction

(2013) E. Styles et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Salmonella Type III Effector SspH2 Specifically Exploits the NLR Co-chaperone Activity of SGT1 to Subvert Immunity

(2013) Amit P. Bhavsar et al.   PLoS Pathogens

Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses

(2012) Na Dong et al.   CELL

Expression of Pseudomonas syringae type III effectors in yeast under stress conditions reveals that HopX1 attenuates activation of the high osmolarity glycerol MAP kinase pathway

(2012) D. Salomon et al.   MICROBIOLOGY-SGM

The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae

(2012) Pablo Fernandez-Piñar et al.   MOLECULAR BIOLOGY OF THE CELL

TheawrGene Family Encodes a Novel Class ofRalstonia solanacearumType III Effectors Displaying Virulence and Avirulence Activities

(2012) Montserrat Solé et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Programmed cell death in the plant immune system

(2011) N S Coll et al.   CELL DEATH AND DIFFERENTIATION

Mimicking GEFs: a common theme for bacterial pathogens

(2011) Robert C. Orchard et al.   CELLULAR MICROBIOLOGY

Identification ofVibrio choleraeType III Secretion System Effector Proteins

(2011) Ashfaqul Alam et al.   INFECTION AND IMMUNITY

Interaction of the Salmonella Typhimurium effector protein SopB with host cell Cdc42 is involved in intracellular replication

(2011) Isabel Rodríguez-Escudero et al.   MOLECULAR MICROBIOLOGY

Ubiquitin and ubiquitin-modified proteins activate the Pseudomonas aeruginosa T3SS cytotoxin, ExoU

(2011) David M. Anderson et al.   MOLECULAR MICROBIOLOGY

A Simple Yeast-Based Strategy to Identify Host Cellular Processes Targeted by Bacterial Effector Proteins

(2011) Eran Bosis et al.   PLoS One

Biochemistry and cell signaling taught by bacterial effectors

(2011) Jixin Cui et al.   TRENDS IN BIOCHEMICAL SCIENCES

Expressing the Erwinia amylovora type III effector DspA/E in the yeast Saccharomyces cerevisiae strongly alters cellular trafficking

(2011) Sabrina Siamer et al.   FEBS Open Bio

Regulation of cross-talk in yeast MAPK signaling pathways

(2010) Haruo Saito   CURRENT OPINION IN MICROBIOLOGY

Expression ofXanthomonas campestrispv.vesicatoriaType III Effectors in Yeast Affects Cell Growth and Viability

(2010) Dor Salomon et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

The assembly of a GTPase–kinase signalling complex by a bacterial catalytic scaffold

(2010) Andrey S. Selyunin et al.   NATURE

Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

(2010) Anastasia Baryshnikova et al.   NATURE METHODS

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Development of a Novel Functional High-Throughput Screening System for Pathogen Effectors in the YeastSaccharomyces cerevisiae

(2009) Mitsuaki TABUCHI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Host–microbe interactions: bacteria

(2009) Brendan Kenny et al.   CURRENT OPINION IN MICROBIOLOGY

Yeast as a tool to study bacterial effectors

(2009) Jasna Curak et al.   CURRENT OPINION IN MICROBIOLOGY

A yeast-based genetic screen for identification of pathogenicSalmonella proteins

(2009) Ainel Alemán et al.   FEMS MICROBIOLOGY LETTERS

Multiple Activities of the Plant Pathogen Type III Effector Proteins WtsE and AvrE Require WxxxE Motifs

(2009) Jong Hyun Ham et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Pseudomonas syringae pv. tomato DC3000 Type III Effector HopAA1-1 Functions Redundantly with Chlorosis-Promoting Factor PSPTO4723 to Produce Bacterial Speck Lesions in Host Tomato

(2009) Kathy R. Munkvold et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics

(2009) Zhiwei Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Deletions in the Repertoire of Pseudomonas syringae pv. tomato DC3000 Type III Secretion Effector Genes Reveal Functional Overlap among Effectors

(2009) Brian H. Kvitko et al.   PLoS Pathogens

The Yeast Saccharomyces cerevisiae: A Versatile Model System for the Identification and Characterization of Bacterial Virulence Proteins

(2008) Keri A. Siggers et al.   Cell Host & Microbe

Quantification of Real-Time Salmonella Effector Type III Secretion Kinetics Reveals Differential Secretion Rates for SopE2 and SptP

(2008) Schuyler B. VanEngelenburg et al.   CHEMISTRY & BIOLOGY

YspM, a Newly Identified Ysa Type III Secreted Protein of Yersinia enterocolitica

(2008) S. E. Witowski et al.   JOURNAL OF BACTERIOLOGY

WtsE, an AvrE-family type III effector protein ofPantoea stewartiisubsp.stewartii, causes cell death in non-host plants

(2008) JONG HYUN HAM et al.   MOLECULAR PLANT PATHOLOGY

A Survey of thePseudomonas syringaepv.tomatoDC3000 Type III Secretion System Effector Repertoire Reveals Several Effectors That Are Deleterious When Expressed inSaccharomyces cerevisiae

(2008) Kathy R. Munkvold et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

The essential role of the CopN protein in Chlamydia pneumoniae intracellular growth

(2008) Jin Huang et al.   NATURE

Crosstalk between small GTPases and polarity proteins in cell polarization

(2008) Sandra Iden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Functional Genomic Yeast Screen to Identify Pathogenic Bacterial Proteins

(2008) Naomi L. Slagowski et al.   PLoS Pathogens

Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen

(2008) Anthony Arnoldo et al.   PLoS Genetics