Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine

Title
Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine
Authors
Keywords
Viral replication, Poliovirus, Vaccines, Microbial mutation, Antigens, RNA viruses, Internal ribosome entry site, Attenuated vaccines
Journal
PLoS Pathogens
Volume 12, Issue 3, Pages e1005483
Publisher
Public Library of Science (PLoS)
Online
2016-04-01
DOI
10.1371/journal.ppat.1005483

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