Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a
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Title
Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a
Authors
Keywords
Vaccines, Typhoid, Salmonella typhi, Antibodies, Vaccination and immunization, Blood, Fevers, Vaccine development
Journal
PLoS Neglected Tropical Diseases
Volume 10, Issue 8, Pages e0004926
Publisher
Public Library of Science (PLoS)
Online
2016-08-18
DOI
10.1371/journal.pntd.0004926
References
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Related references
Note: Only part of the references are listed.- Design, recruitment, and microbiological considerations in human challenge studies
- (2015) Thomas C Darton et al. LANCET INFECTIOUS DISEASES
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- (2015) Franklin R. Toapanta et al. PLoS Neglected Tropical Diseases
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- Serum Bactericidal Assays To Evaluate Typhoidal and Nontyphoidal Salmonella Vaccines
- (2014) Mary Adetinuke Boyd et al. Clinical and Vaccine Immunology
- An Outpatient, Ambulant-Design, Controlled Human Infection Model Using Escalating Doses of Salmonella Typhi Challenge Delivered in Sodium Bicarbonate Solution
- (2014) Claire S. Waddington et al. CLINICAL INFECTIOUS DISEASES
- Advancing the management and control of typhoid fever: A review of the historical role of human challenge studies
- (2014) Claire S. Waddington et al. JOURNAL OF INFECTION
- Complex Adaptive Immunity to Enteric Fevers in Humans: Lessons Learned and the Path Forward
- (2014) Marcelo B. Sztein et al. Frontiers in Immunology
- Self-reported illness and household strategies for coping with health-care payments in Bangladesh
- (2013) Md Mizanur Rahman et al. BULLETIN OF THE WORLD HEALTH ORGANIZATION
- Head-to-Head Comparison of Humoral Immune Responses to Vi Capsular Polysaccharide and Salmonella Typhi Ty21a Typhoid Vaccines–A Randomized Trial
- (2013) Anu Kantele et al. PLoS One
- Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
- (2012) Rafael Lozano et al. LANCET
- Antibodies in Action: Role of Human Opsonins in Killing Salmonella enterica Serovar Typhi
- (2011) Janet C. Lindow et al. INFECTION AND IMMUNITY
- Ex Vivo Kinetics of Early and Long-Term Multifunctional Human Leukocyte Antigen E-Specific CD8+ Cells in Volunteers Immunized with the Ty21a Typhoid Vaccine
- (2010) R. Salerno-Goncalves et al. Clinical and Vaccine Immunology
- A Randomised Trial Evaluating the Safety and Immunogenicity of the Novel Single Oral Dose Typhoid Vaccine M01ZH09 in Healthy Vietnamese Children
- (2010) Tran Tinh Hien et al. PLoS One
- In a randomized, double-blinded, placebo-controlled trial, the single oral dose typhoid vaccine, M01ZH09, is safe and immunogenic at doses up to 1.7×1010 colony-forming units
- (2010) C.E. Lyon et al. VACCINE
- a study of typhoid fever in five Asian countries: disease burden and implications for controls
- (2008) R Leon Ochiai BULLETIN OF THE WORLD HEALTH ORGANIZATION
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