Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients

Optimizing celgosivir therapy in mouse models of dengue virus infection of serotypes 1 and 2: The search for a window for potential therapeutic efficacy

(2016) Satoru Watanabe et al.   ANTIVIRAL RESEARCH

Protective and immunological behavior of chimeric yellow fever dengue vaccine

(2016) Scott B. Halstead et al.   VACCINE

Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease

(2015) Sri Rezeki Hadinegoro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy of a Tetravalent Dengue Vaccine in Children in Latin America

(2015) Luis Villar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination

(2015) P. Robert Beatty et al.   Science Translational Medicine

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

(2015) Naphak Modhiran et al.   Science Translational Medicine

Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints

(2015) October M. Sessions et al.   PLoS Neglected Tropical Diseases

Tracking Dengue Virus Intra-host Genetic Diversity during Human-to-Mosquito Transmission

(2015) Shuzhen Sim et al.   PLoS Neglected Tropical Diseases

RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies

(2014) Alexandros Stamatakis   BIOINFORMATICS

Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial

(2014) Maria Rosario Capeding et al.   LANCET

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial

(2014) Jenny G Low et al.   LANCET INFECTIOUS DISEASES

Secondary infection as a risk factor for dengue hemorrhagic fever/dengue shock syndrome: an historical perspective and role of antibody-dependent enhancement of infection

(2013) Maria G. Guzman et al.   ARCHIVES OF VIROLOGY

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

The global distribution and burden of dengue

(2013) Samir Bhatt et al.   NATURE

Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial

(2012) Satoru Watanabe et al.   ANTIVIRAL RESEARCH

Dynamic analysis of Th1/Th2 cytokine concentration during antiretroviral therapy of HIV-1/HCV co-infected Patients

(2012) Wenzhen Kang et al.   BMC INFECTIOUS DISEASES

Effects of Short-Course Oral Corticosteroid Therapy in Early Dengue Infection in Vietnamese Patients: A Randomized, Placebo-Controlled Trial

(2012) D. T. H. Tam et al.   CLINICAL INFECTIOUS DISEASES

A Randomized, Double-Blind Placebo Controlled Trial of Balapiravir, a Polymerase Inhibitor, in Adult Dengue Patients

(2012) Nguyet Minh Nguyen, Chau Nguyen Bich Tran, Lam Khanh Phung, Kien Thi Hue Duong, Huy le Anh Huynh, Jeremy Farrar, Quyen Than Ha Nguyen, Hien Tinh Tran, Chau Van Vinh Nguyen, Laura Merson, Long Truong Hoang, Martin L. Hibberd, Pauline P. K. Aw, Andreas Wilm, Niranjan Nagarajan, Dung Thi Nguyen et al.   JOURNAL OF INFECTIOUS DISEASES

LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets

(2012) Andreas Wilm et al.   NUCLEIC ACIDS RESEARCH

Evaluation of the NS1 Rapid Test and the WHO Dengue Classification Schemes for Use as Bedside Diagnosis of Acute Dengue Fever in Adults

(2011) Shera Chaterji et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model

(2011) Abhay P.S. Rathore et al.   ANTIVIRAL RESEARCH

Dengue virus surveillance in Singapore reveals high viral diversity through multiple introductions and in situ evolution

(2011) Kim-Sung Lee et al.   INFECTION GENETICS AND EVOLUTION

High-Resolution Analysis of Intrahost Genetic Diversity in Dengue Virus Serotype 1 Infection Identifies Mixed Infections

(2011) K. T. D. Thai et al.   JOURNAL OF VIROLOGY

Kinetics of Viremia and NS1 Antigenemia Are Shaped by Immune Status and Virus Serotype in Adults with Dengue

(2011) Vianney Tricou et al.   PLoS Neglected Tropical Diseases

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

A Randomized Controlled Trial of Chloroquine for the Treatment of Dengue in Vietnamese Adults

(2010) Vianney Tricou et al.   PLoS Neglected Tropical Diseases

Update on Dengue: Epidemiology, Virus Evolution, Antiviral Drugs, and Vaccine Development

(2010) Annelies Wilder-Smith et al.   Current Infectious Disease Reports

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS