Review
Cardiac & Cardiovascular Systems
Matteo Monami, Riccardo Candido, Basilio Pintaudi, Giovanni Targher, Edoardo Mannucci
Summary: This meta-analysis suggests that metformin is associated with a lower risk of major adverse cardiovascular events (MACEs) and tendentially lower all-cause mortality compared to placebo or other anti-hyperglycaemic drugs.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Cardiac & Cardiovascular Systems
Edoardo Mannucci, Andrea Giaccari, Marco Gallo, Giovanni Targher, Basilio Pintaudi, Riccardo Candido, Matteo Monami
Summary: The meta-analysis found that pioglitazone did not significantly increase or decrease the risk of major adverse cardiovascular events (MACEs), all-cause mortality, and hospitalization for heart failure (HHF) when compared with placebo or active comparators. However, pioglitazone was associated with a significant reduction in MACE risk in patients with prior cardiovascular events.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Review
Cardiac & Cardiovascular Systems
Edoardo Mannucci, Giovanni Targher, Besmir Nreu, Basilio Pintaudi, Riccardo Candido, Andrea Giaccari, Marco Gallo, Matteo Monami
Summary: This article presents a meta-analysis on the effect of insulin treatment for type 2 diabetes. The results show that insulin treatment does not significantly increase or reduce the risk of major adverse cardiovascular events, all-cause mortality, and hospitalization for heart failure, compared to placebo or other active control treatments.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Cardiac & Cardiovascular Systems
Bin Zhang, Zhi-Fei Li, Zhuo-Yu An, Li Zhang, Jing-Yi Wang, Meng-Di Hao, Yi-Jing Jin, Dong Li, An-Jian Song, Qiang Ren, Wen-Biao Chen
Summary: The study found that asthma patients have an increased risk of cardiovascular disease morbidity and mortality, as well as all-cause mortality. Female asthma patients have a higher risk of cardiovascular disease morbidity and all-cause mortality, and late-onset asthma patients have a higher risk of cardiovascular disease morbidity.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Maciej Banach, Joanna Lewek, Stanislaw Surma, Peter E. Penson, Amirhossein Sahebkar, Seth S. Martin, Gani Bajraktari, Michael Y. Henein, Zeljko Reiner, Agata Bielecka-Dabrowa, Ibadete Bytyci
Summary: There is a significant inverse association between daily step count and all-cause mortality and cardiovascular mortality. Different ages, genders, and regional differences play a role in this association. Additionally, walking as few as 2500/4000 steps per day can already bring health benefits.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Edoardo Mannucci, Marco Gallo, Basilio Pintaudi, Giovanni Targher, Riccardo Candido, Andrea Giaccari, Matteo Monami
Summary: The effects of alpha-glucosidase inhibitors on all-cause mortality and major cardiovascular events are inconclusive based on current evidence. This meta-analysis did not find a significant increase in all-cause mortality with alpha-glucosidase inhibitors compared to other therapies or placebo.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Review
Nutrition & Dietetics
Nikan Zargarzadeh, Seyed Mohammad Mousavi, Heitor O. Santos, Dagfinn Aune, Shirin Hasani-Ranjbar, Bagher Larijani, Ahmad Esmaillzadeh
Summary: This study examined the potential dose-response relationship between legume consumption and mortality rates in the general population. The results showed that higher legume intake was associated with a reduced risk of all-cause and stroke mortality, but there was no significant association with cardiovascular disease, coronary heart disease, and cancer mortality.
ADVANCES IN NUTRITION
(2023)
Review
Nutrition & Dietetics
Seyed Mohammad Mousavi, Nikan Zargarzadeh, Somaye Rigi, Emma Persad, Ana Beatriz Pizarro, Shirin Hasani-Ranjbar, Bagher Larijani, Walter C. Willett, Ahmad Esmaillzadeh
Summary: The study found that higher egg consumption was not associated with mortality from all causes, cardiovascular disease, coronary heart disease, stroke, or respiratory disease. However, it was associated with an increased risk of cancer mortality. Each additional egg per week consumption was associated with a 2% and 4% increased risk of all-cause and cancer mortality, respectively. The certainty of the evidence was rated as low to moderate.
ADVANCES IN NUTRITION
(2022)
Article
Critical Care Medicine
Hong Chen, Zheng-Xu Deng, Jian Sun, Qiang Huang, Lan Huang, Yong-Hong He, Chunlan Ma, Ke Wang
Summary: Inhaled therapy containing ICSs, especially triple therapy, can reduce the all-cause mortality risk in patients with COPD. Predictors of this association include medication factors and patient characteristics, with eosinophil counts of ≥200/mL being the strongest predictor.
Review
Nutrition & Dietetics
Jiaqi Yang, Yulin Zhang, Xiaona Na, Ai Zhao
Summary: This study conducted a systematic review and meta-analysis on the associations between beta-carotene supplementation and cardiovascular disease (CVD) risk. The results showed that beta-carotene supplementation had no beneficial effects on CVD incidence and could potentially increase cardiovascular mortality. Smoking behavior was also found to be associated with increased cardiovascular incidence and mortality in the beta-carotene intervention group.
Article
Endocrinology & Metabolism
Juan Xu, Yimeng Sun, Dandan Gong, Yu Fan
Summary: This meta-analysis study found that preexisting diabetes has a significant impact on cardiovascular and all-cause mortality in patients with atrial fibrillation. Patients with diabetes have a higher risk of death.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Geriatrics & Gerontology
Yang Peng, Guo-Chao Zhong, Xiaoli Zhou, Lijuan Guan, Lihua Zhou
Summary: This meta-analysis explored the associations of frailty with all-cause and cause-specific mortality. The findings revealed that frailty was significantly associated with an increased risk of all-cause mortality and was a strong predictor of cause-specific mortality from cardiovascular disease, cancer, and respiratory illness in community-dwelling adults. Further studies are needed to clarify the relationship between frailty and cause-specific mortality from dementia, infection, and COVID-19.
Review
Endocrinology & Metabolism
Dimitris Varvaki Rados, Mariana Rangel Ribeiro Falcetta, Lana Catani Pinto, Cristiane Bauermann Leitao, Jorge Luiz Gross
Summary: The study found that insulin treatment in patients with type 2 diabetes does not increase the risk of cardiovascular events or death, but does increase the risk of hypoglycemia.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Cardiac & Cardiovascular Systems
Byron C. Jaeger, Adam P. Bress, Joshua D. Bundy, Alfred K. Cheung, William C. Cushman, Paul E. Drawz, Karen C. Johnson, Cora E. Lewis, Suzanne Oparil, Michael Rocco, Stephen R. Rapp, Mark A. Supiano, Paul K. Whelton, Jeff D. Williamson, Jackson T. Wright, David M. Reboussin, Nicholas M. Pajewski
Summary: This study examines the long-term effects of intensive blood pressure control on cardiovascular and all-cause mortality. It found that although intensive treatment was beneficial during the intervention period, the benefits did not persist after the trial ended.
Article
Nutrition & Dietetics
Shamima Akter, Tetsuya Mizoue, Akiko Nanri, Atsushi Goto, Mitsuhiko Noda, Norie Sawada, Taiki Yamaji, Motoki Iwasaki, Manami Inoue, Shoichiro Tsugane
Summary: The study found a U-shaped association between low-carbohydrate diet (LCD) score and total mortality among Asians, with high animal protein and fat in LCD associated with higher mortality risk. Conversely, a LCD high in plant-based sources of protein and fat was associated with a lower risk of total and cardiovascular mortality.
CLINICAL NUTRITION
(2021)
Article
Health Care Sciences & Services
Karen B. Ruschel, Dimitris R. Rados, Mariana Furtado, Joanna d'Arc L. Batista, Natan Katz, Erno Harzheim, Carisi A. Polanczyk
Summary: This study aimed to evaluate the safety and efficacy of teleconsultations as support in the care transition of patients with stable coronary artery disease (CAD). The results showed that telemedicine was safe for patients with stable CAD and had noninferiority in controlling risk factors and clinical outcomes compared to traditional outpatient care.
JOURNAL OF TELEMEDICINE AND TELECARE
(2022)
Article
Cell Biology
Bianca M. de Souza, Michelle Rodrigues, Fernanda S. de Oliveira, Liana P. A. da Silva, Ana P. Boucas, Ciro P. Portinho, Bruno P. dos Santos, Melissa Camassola, Dagoberto Rocha, Simone Lysakowski, Juliano Martini, Cristiane B. Leitao, Nance B. Nardi, Andrea C. Bauer, Daisy Crispim
MOLECULAR AND CELLULAR ENDOCRINOLOGY
(2020)
Review
Endocrinology & Metabolism
Marcello Casaccia Bertoluci, Joao Eduardo Nunes Salles, Jose Silva-Nunes, Hermelinda Cordeiro Pedrosa, Rodrigo Oliveira Moreira, Rui Manuel Calado da Silva Duarte, Davide Mauricio Costa Carvalho, Fabio Rogerio Trujilho, Joao Filipe Cancela dos Santos Raposo, Erika Bezerra Parente, Fernando Valente, Fabio Ferreira de Moura, Alexandre Hohl, Miguel Melo, Francisco Garcia Pestana Araujo, Rosa Maria Monteiro Castro de Araujo Principe, Rosane Kupfer, Adriana Costa e Forti, Cynthia Melissa Valerio, Helder Jose Ferreira, Joao Manuel Sequeria Duarte, Jose Francisco Kerr Saralva, Melanie Rodacki, Maria Helane Costa Gurgel Castelo, Mariana Pereira Monteiro, Patricia Quadros Branco, Pedro Manuel Patricio de Matos, Pedro Carneiro de Melo Pereira de Magalhaes, Roberto Tadeu Barcellos Betti, Rosangela Roginski Rea, Thaisa Dourado Guedes Trujilho, Lana Catani Ferreira Pinto, Cristiane Bauermann Leitao
DIABETOLOGY & METABOLIC SYNDROME
(2020)
Article
Ophthalmology
Aline Lutz de Araujo, Dimitris Rucks Varvaki Rados, Anelise Decavata Szortyka, Maicon Falavigna, Tais de Campos Moreira, Lisiane Hauser, Paula Blasco Gross, Andrea Longoni Lorentz, Lucas Maturro, Felipe Cabral, Ana Luiza Fontes de Azevedo Costa, Thiago Goncalves dos Santos Martins, Rodolfo Souza da Silva, Paulo Schor, Erno Harzheim, Marcelo Rodrigues Goncalves, Roberto Nunes Umpierre
Summary: The study found that ophthalmic images acquired by a trained nurse technician consistently achieved over 90% adequacy for remote reading, with a high overall agreement compared to images acquired by ophthalmologists. This provides favorable evidence of the adequacy of teleophthalmological imaging by nurse technicians.
Review
Endocrinology & Metabolism
Lana C. Pinto, Dimitris Rados, Luciana R. Remonti, Luciana V. Viana, Georgia T. Pulz, Mariana P. Carpena, Roberta P. Borges, Roberta Marobin, Mileni Beretta, Elis F. Pedrollo, Thiza M. Londero, Rafael Machry, Lais Janeczko, Milene Moehlecke, Mariana R. Falcetta, Andrea C. Bauer, Sandra P. Silveiro, Fernando Gerchman, Ticiana C. Rodrigues, Caroline K. Kramer, Marcello C. Bertoluci, Cristiane B. Leitao
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2020)
Article
Health Care Sciences & Services
Juliana N. Pfeil, Dimitris Rados, Rudi Roman, Natan Katz, Luciana N. Nunes, Alvaro Vigo, Erno Harzheim
Summary: The telemedicine programme RegulaSUS in the state of Rio Grande do Sul, Brazil, has been shown to effectively reduce referral-to-consultation time and decrease the number of waitlisted patients, enabling sicker patients to reach specialists faster.
JOURNAL OF TELEMEDICINE AND TELECARE
(2023)
Article
Multidisciplinary Sciences
Laryssa P. T. Hanauer, Pedro H. Comerlato, Afonso Papke, Marina Butzke, Andressa Daga, Mariana C. Hoffmeister, Marcio M. Boniatti, Josiane F. John, Beatriz D. Schaan, Dimitris Rados
SCIENTIFIC REPORTS
(2020)
Review
Endocrinology & Metabolism
Dimitris Varvaki Rados, Mariana Rangel Ribeiro Falcetta, Lana Catani Pinto, Cristiane Bauermann Leitao, Jorge Luiz Gross
Summary: The study found that insulin treatment in patients with type 2 diabetes does not increase the risk of cardiovascular events or death, but does increase the risk of hypoglycemia.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Multidisciplinary Sciences
Lilian Rodrigues Henrique, Daisy Crispim, Tarsila Vieceli, Ariell Freires Schaeffer, Priscila Bellaver, Cristiane Bauermann Leitao, Tatiana Helena Rech
Summary: This study found no significant correlations between copeptin levels and glycemic parameters, suggesting copeptin may not be a relevant factor in inducing hyperglycemia during critical illness. However, copeptin levels on ICU day 3 were higher in survivors compared to non-survivors.
Article
Surgery
Mayara S. de Oliveira, Michelle Rodrigues, Elis A. Rossoni, Denise A. Sortica, Jakeline Rheinheimer, Milene Moehlecke, Mariana L. D. C. Heredia, Jaqueline D. C. Horvath, Natalia L. Kops, Manoel R. M. Trindade, Luciana V. Viana, Cristiane B. Leita, Rogerio Friedman, Daisy Crispim, Bianca M. de Souza
Summary: This study investigated the association of UCP2 -866G/A and Ins/Del polymorphisms with weight loss outcomes after bariatric surgery. Findings suggest that the -866A/A genotype is associated with higher BMI, excess weight, and lower EWL% during an 18-month follow-up, while the Ins allele may be linked to lower DBMI 12 months after surgery. Further research is needed to confirm these associations.
SURGERY FOR OBESITY AND RELATED DISEASES
(2021)
Article
Multidisciplinary Sciences
Cassia Garcia Moraes Pagano, Tais de Campos Moreira, Daniel Sganzerla, Ana Maria Frolich Matzenbacher, Amanda Gomes Faria, Lucas Matturro, Felipe Cezar Cabral, Dimitris Rucks Varvaki Rados, Anelise Decavata Szortyka, Maicon Falavigna, Maria Eulalia Vinade Chagas, Erno Harzheim, Marcelo Goncalves, Roberto Umpierre, Aline Lutz de Araujo
Summary: The study demonstrates that remote collection of ophthalmological data by properly trained health professionals is feasible, confirming the utility and safety of these solutions in scenarios where access to ophthalmologists is restricted.
Review
Health Care Sciences & Services
Ana Marina Moreira, Roberta Marobin, Gustavo Monteiro Escott, Dimitris Varvaki Rados, Sandra Pinho Silveiro
Summary: This study systematically evaluated the effect of telephone call intervention on glycemic control in patients with type 2 diabetes, showing that it can improve glycemic control, particularly when combined with pharmacological treatment modification and delivered by nurses.
JOURNAL OF TELEMEDICINE AND TELECARE
(2022)
Review
Endocrinology & Metabolism
Lana C. Pinto, Dimitris Rados, Luciana R. Remonti, Marina V. Viana, Cristiane B. Leitao, Jorge L. Gross
Summary: This study compared the effects of different doses of commercially available SGLT2 inhibitors on HbA1c and body weight in patients with type 2 diabetes in Brazil. The results showed that different doses of empagliflozin had similar effects on HbA1c, body weight, and other factors, while a dose of 300mg of canagliflozin had the strongest effects in reducing HbA1c and body weight.
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2022)