A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation

Quantitative Reduction of the TCR Adapter Protein SLP-76 Unbalances Immunity and Immune Regulation

(2015) Owen M. Siggs et al.   JOURNAL OF IMMUNOLOGY

TCR signal quantity and quality in CD4+ T cell differentiation

(2014) Noah J. Tubo et al.   TRENDS IN IMMUNOLOGY

Early signaling events that underlie fate decisions of naive CD4+T cells toward distinct T-helper cell subsets

(2013) Hidehiro Yamane et al.   IMMUNOLOGICAL REVIEWS

Suppression of Inflammatory Responses during Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis Is Regulated by AKT3 Signaling

(2013) V. Tsiperson et al.   JOURNAL OF IMMUNOLOGY

Mechanism for p38α-mediated Experimental Autoimmune Encephalomyelitis

(2012) Kana Namiki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism and function of Vav1 localisation in TCR signalling

(2012) Olga Ksionda et al.   JOURNAL OF CELL SCIENCE

Polar Opposites: Erk Direction of CD4 T Cell Subsets

(2012) C.-F. Chang et al.   JOURNAL OF IMMUNOLOGY

PI3K-Akt-mTORC1-S6K1/2 Axis Controls Th17 Differentiation by Regulating Gfi1 Expression and Nuclear Translocation of RORγ

(2012) Yutaka Kurebayashi et al.   Cell Reports

Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitis

(2011) R. Noubade et al.   BLOOD

The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development

(2011) Céline Colacios et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

Vav1-Mediated Scaffolding Interactions Stabilize SLP-76 Microclusters and Contribute to Antigen-Dependent T Cell Responses

(2011) N. R. Sylvain et al.   Science Signaling

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Loss of the LAT Adaptor Converts Antigen-Responsive T Cells into Pathogenic Effectors that Function Independently of the T Cell Receptor

(2009) Michael Mingueneau et al.   IMMUNITY

Inhibition of ERK MAPK Suppresses IL-23- and IL-1-Driven IL-17 Production and Attenuates Autoimmune Disease

(2009) C. F. Brereton et al.   JOURNAL OF IMMUNOLOGY

Agouti C57BL/6N embryonic stem cells for mouse genetic resources

(2009) Stephen J Pettitt et al.   NATURE METHODS

Function of the Nucleotide Exchange Activity of Vav1 in T Cell Development and Activation

(2009) A. Saveliev et al.   Science Signaling

A Role for VAV1 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

(2009) M. Jagodic et al.   Science Translational Medicine