A Novel Zebrafish ret Heterozygous Model of Hirschsprung Disease Identifies a Functional Role for mapk10 as a Modifier of Enteric Nervous System Phenotype Severity

Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse

(2016) Ellen Merrick Schill et al.   DEVELOPMENTAL BIOLOGY

JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships

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Functional Loss of Semaphorin 3C and/or Semaphorin 3D and Their Epistatic Interaction with Ret Are Critical to Hirschsprung Disease Liability

(2015) Qian Jiang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy

(2015) J. W. McGreevy et al.   Disease Models & Mechanisms

Building a second brain in the bowel

(2015) Marina Avetisyan et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic compensation induced by deleterious mutations but not gene knockdowns

(2015) Andrea Rossi et al.   NATURE

Colonizing while migrating: how do individual enteric neural crest cells behave?

(2014) Heather M Young et al.   BMC BIOLOGY

The neural crest cell cycle is related to phases of migration in the head

(2014) D. A. Ridenour et al.   DEVELOPMENT

Making designer mutants in model organisms

(2014) Y. Peng et al.   DEVELOPMENT

SRY interference of normal regulation of the RET gene suggests a potential role of the Y-chromosome gene in sexual dimorphism in Hirschsprung disease

(2014) Yunmin Li et al.   HUMAN MOLECULAR GENETICS

Ssrp1a controls organogenesis by promoting cell cycle progression and RNA synthesis

(2013) K. Koltowska et al.   DEVELOPMENT

Contribution of rare and common variants determine complex diseases—Hirschsprung disease as a model

(2013) Maria M. Alves et al.   DEVELOPMENTAL BIOLOGY

Hirschsprung-like disease is exacerbated by reduced de novo GMP synthesis

(2013) Jonathan I. Lake et al.   JOURNAL OF CLINICAL INVESTIGATION

Neural stem cell therapies for enteric nervous system disorders

(2013) Alan J. Burns et al.   Nature Reviews Gastroenterology & Hepatology

TAL Effector Specificity for base 0 of the DNA Target Is Altered in a Complex, Effector- and Assay-Dependent Manner by Substitutions for the Tryptophan in Cryptic Repeat –1

(2013) Erin L. Doyle et al.   PLoS One

Building a brain in the gut: development of the enteric nervous system

(2012) AM Goldstein et al.   CLINICAL GENETICS

The enteric nervous system

(2012) Valentina Sasselli et al.   DEVELOPMENTAL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Development and developmental disorders of the enteric nervous system

(2012) Florian Obermayr et al.   Nature Reviews Gastroenterology & Hepatology

The enteric nervous system and neurogastroenterology

(2012) John B. Furness   Nature Reviews Gastroenterology & Hepatology

Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome

(2012) Timothy J. Dahlem et al.   PLoS Genetics

Hirschsprung disease: a developmental disorder of the enteric nervous system

(2012) Sonja J. McKeown et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Following the genes: a framework for animal modeling of psychiatric disorders

(2011) Kevin J Mitchell et al.   BMC BIOLOGY

Ret signalling integrates a craniofacial muscle module during development

(2011) R. D. Knight et al.   DEVELOPMENT

Genomic contributions to Mendelian disease

(2011) A. Chakravarti   GENOME RESEARCH

Mouse models of cystic fibrosis: Phenotypic analysis and research applications

(2011) Martina Wilke et al.   Journal of Cystic Fibrosis

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

(2011) Tomas Cermak et al.   NUCLEIC ACIDS RESEARCH

Copy Number Variants in Candidate Genes Are Genetic Modifiers of Hirschsprung Disease

(2011) Qian Jiang et al.   PLoS One

Generation of Highly Homogeneous Strains of Zebrafish Through Full Sib-Pair Mating

(2011) Minori Shinya et al.   G3-Genes Genomes Genetics

Differential Contributions of Rare and Common, Coding and Noncoding Ret Mutations to Multifactorial Hirschsprung Disease Liability

(2010) Eileen Sproat Emison et al.   AMERICAN JOURNAL OF HUMAN GENETICS

zTrap: zebrafish gene trap and enhancer trap database

(2010) Koichi Kawakami et al.   BMC DEVELOPMENTAL BIOLOGY

The genetics of neurodevelopmental disease

(2010) Kevin J Mitchell   CURRENT OPINION IN NEUROBIOLOGY

Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation

(2010) Jungwon Seo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Neurochemical coding of enteric neurons in adult and embryonic zebrafish (Danio rerio)

(2010) Leen Uyttebroek et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Hirschsprung's disease

(2010) Simon E. Kenny et al.   Seminars in Pediatric Surgery

Practical pathology and genetics of Hirschsprung's disease

(2009) Raj P. Kapur   Seminars in Pediatric Surgery

A Primer for Morpholino Use in Zebrafish

(2009) Brent R. Bill et al.   Zebrafish

Disturbances of colonic motility in mouse models of Hirschsprung's disease

(2008) Rachael R. Roberts et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Ret isoform function and marker gene expression in the enteric nervous system is conserved across diverse vertebrate species

(2008) Tiffany A. Heanue et al.   MECHANISMS OF DEVELOPMENT

Robust single-particle tracking in live-cell time-lapse sequences

(2008) Khuloud Jaqaman et al.   NATURE METHODS

Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish

(2008) K. Asakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA