The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia

miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia

(2016) Xi Jiang et al.   Nature Communications

miR-22 as a prognostic factor targets glucose transporter protein type 1 in breast cancer

(2015) Bo Chen et al.   CANCER LETTERS

A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis

(2014) L.-M. Kong et al.   CANCER RESEARCH

Transcriptional network control of normal and leukaemic haematopoiesis

(2014) Jonathan I. Sive et al.   EXPERIMENTAL CELL RESEARCH

Activation of the PI3K/AKT pathway by microRNA-22 results in CLL B-cell proliferation

(2014) F Palacios et al.   LEUKEMIA

MiR-181 family: regulators of myeloid differentiation and acute myeloid leukemia as well as potential therapeutic targets

(2014) R Su et al.   ONCOGENE

The role, mechanism and potentially therapeutic application of microRNA-29 family in acute myeloid leukemia

(2013) J-N Gong et al.   CELL DEATH AND DIFFERENTIATION

The Oncogenic MicroRNA miR-22 Targets the TET2 Tumor Suppressor to Promote Hematopoietic Stem Cell Self-Renewal and Transformation

(2013) Su Jung Song et al.   Cell Stem Cell

Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors

(2013) Gillian May et al.   Cell Stem Cell

MicroRNA-22 Regulates Cardiac Hypertrophy and Remodeling in Response to Stress

(2013) Zhan-Peng Huang et al.   CIRCULATION RESEARCH

A Novel p53/microRNA-22/Cyr61 Axis in Synovial Cells Regulates Inflammation in Rheumatoid Arthritis

(2013) Jinpiao Lin et al.   Arthritis & Rheumatology

MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia

(2012) X.-S. Wang et al.   BLOOD

Targeted Deletion of MicroRNA-22 Promotes Stress-Induced Cardiac Dilation and Contractile Dysfunction

(2012) Priyatansh Gurha et al.   CIRCULATION

Emerging Roles of MicroRNA-22 in Human Disease and Normal Physiology

(2012) J. Xiong   CURRENT MOLECULAR MEDICINE

MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells

(2012) Silvia Alvarez-Díaz et al.   HUMAN MOLECULAR GENETICS

Tumor suppressor miR-22 suppresses lung cancer cell progression through post-transcriptional regulation of ErbB3

(2012) Bo Ling et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Deregulated Expression of EVI1 Defines a Poor Prognostic Subset of MLL-Rearranged Acute Myeloid Leukemias: A Study of the German-Austrian Acute Myeloid Leukemia Study Group and the Dutch-Belgian-Swiss HOVON/SAKK Cooperative Group

(2012) Stefan Gröschel et al.   JOURNAL OF CLINICAL ONCOLOGY

Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells

(2012) O S Kustikova et al.   LEUKEMIA

miR-22 Controls Irf8 mRNA Abundance and Murine Dendritic Cell Development

(2012) Haiyan S. Li et al.   PLoS One

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

(2011) S. Ghani et al.   BLOOD

Tumor Suppressor miR-22 Determines p53-Dependent Cellular Fate through Post-transcriptional Regulation of p21

(2011) N. Tsuchiya et al.   CANCER RESEARCH

Epigenetic silencing of the oncogenic miR-17-92 cluster during PU.1-directed macrophage differentiation

(2011) Vit Pospisil et al.   EMBO JOURNAL

Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity

(2011) Keisuke Kataoka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of Smad signaling in hematopoiesis and translational hematology

(2011) U Blank et al.   LEUKEMIA

HighEVI1Expression Predicts Outcome in Younger Adult Patients With Acute Myeloid Leukemia and Is Associated With Distinct Cytogenetic Abnormalities

(2010) Stefan Gröschel et al.   JOURNAL OF CLINICAL ONCOLOGY

Control of EVI-1 oncogene expression in metastatic breast cancer cells through microRNA miR-22

(2010) J B Patel et al.   ONCOGENE

Silencing of hsa-miR-124 by EVI1 in cell lines and patients with acute myeloid leukemia

(2010) I. Vazquez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EVI1 Impairs Myelopoiesis by Deregulation of PU.1 Function

(2009) Leopoldo Laricchia-Robbio et al.   CANCER RESEARCH

High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated

(2008) S. Lugthart et al.   BLOOD

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

(2008) R. Garzon et al.   BLOOD

MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemia

(2008) M. Jongen-Lavrencic et al.   BLOOD

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

(2008) Jonathan B. Johnnidis et al.   NATURE

MicroRNA Expression in Cytogenetically Normal Acute Myeloid Leukemia

(2008) Guido Marcucci et al.   NEW ENGLAND JOURNAL OF MEDICINE

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

(2008) R. Garzon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA