RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis

RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation

(2015) O. N. Kuvardina et al.   BLOOD

Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells

(2015) Daniel J Trombly et al.   BMC GENOMICS

RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence

(2014) M. Lie-A-Ling et al.   BLOOD

High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias

(2014) Joseph Y. Shin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation

(2014) Adlen Foudi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal

(2014) Anetta Ptasinska et al.   Cell Reports

Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model

(2013) Nina Cabezas-Wallscheid et al.   EMBO Molecular Medicine

Gene mutations of acute myeloid leukemia in the genome era

(2013) Tomoki Naoe et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells

(2013) Susumu Goyama et al.   JOURNAL OF CLINICAL INVESTIGATION

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

(2013) Alejandra Sanjuan-Pla et al.   NATURE

Cell-Autonomous Function of Runx1 Transcriptionally Regulates Mouse Megakaryocytic Maturation

(2013) Niv Pencovich et al.   PLoS One

Addiction of t(8;21) and inv(16) Acute Myeloid Leukemia to Native RUNX1

(2013) Oren Ben-Ami et al.   Cell Reports

Critical role of P1-Runx1 in mouse basophil development

(2012) K. Mukai et al.   BLOOD

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment

(2012) C. Lancrin et al.   BLOOD

A Novel Complex, RUNX1-MYEF2, Represses Hematopoietic Genes in Erythroid Cells

(2012) B. van Riel et al.   MOLECULAR AND CELLULAR BIOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Inferring rules of lineage commitment in haematopoiesis

(2012) Cristina Pina et al.   NATURE CELL BIOLOGY

ENCODE Data in the UCSC Genome Browser: year 5 update

(2012) Kate R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

An encyclopedia of mouse DNA elements (Mouse ENCODE)

(2012) et al.   GENOME BIOLOGY

CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells

(2011) C. Robin et al.   BLOOD

Transcription factor networks in erythroid cell and megakaryocyte development

(2011) L. C. Dore et al.   BLOOD

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

(2011) Nicolas Goardon et al.   CANCER CELL

RUNX1 regulates theCD34gene in haematopoietic stem cells by mediating interactions with a distal regulatory element

(2011) Elena Levantini et al.   EMBO JOURNAL

Runx1 Loss Minimally Impacts Long-Term Hematopoietic Stem Cells

(2011) Xiongwei Cai et al.   PLoS One

The differential activities of Runx1 promoters define milestones during embryonic hematopoiesis

(2009) P. Sroczynska et al.   BLOOD

Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis

(2009) B. Jacob et al.   BLOOD

Alternative Runx1 promoter usage in mouse developmental hematopoiesis

(2009) Thomas Bee et al.   BLOOD CELLS MOLECULES AND DISEASES

Common features of megakaryocytes and hematopoietic stem cells: What's the connection?

(2009) Hui Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

(2009) Christophe Lancrin et al.   NATURE

Ablation of Gata1 in adult mice results in aplastic crisis, revealing its essential role in steady-state and stress erythropoiesis

(2008) L. Gutierrez et al.   BLOOD