Processing Oscillatory Signals by Incoherent Feedforward Loops

Myc and cell cycle control

(2015) Gabriel Bretones et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Frequency modulation of ERK activation dynamics rewires cell fate

(2015) H. Ryu et al.   Molecular Systems Biology

A noisy linear map underlies oscillations in cell size and gene expression in bacteria

(2015) Yu Tanouchi et al.   NATURE

Computational analysis of signaling patterns in single cells

(2015) Denise M. Davis et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Accurate Encoding and Decoding by Single Cells: Amplitude Versus Frequency Modulation

(2015) Gabriele Micali et al.   PLoS Computational Biology

Dynamic expression and roles of Hes factors in neural development

(2014) Ryoichiro Kageyama et al.   CELL AND TISSUE RESEARCH

Ultradian oscillations and pulses: coordinating cellular responses and cell fate decisions

(2014) A. Isomura et al.   DEVELOPMENT

cAMP-responsive Element-binding Protein (CREB) and cAMP Co-regulate Activator Protein 1 (AP1)-dependent Regeneration-associated Gene Expression and Neurite Growth

(2014) Thong C. Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fold Change of Nuclear NF-κB Determines TNF-Induced Transcription in Single Cells

(2014) Robin E.C. Lee et al.   MOLECULAR CELL

Nucleocytoplasmic Shuttling of a GATA Transcription Factor Functions as a Development Timer

(2014) H. Cai et al.   SCIENCE

Logarithmic and Power Law Input-Output Relations in Sensory Systems with Fold-Change Detection

(2014) Miri Adler et al.   PLoS Computational Biology

Encoding and Decoding Cellular Information through Signaling Dynamics

(2013) Jeremy E. Purvis et al.   CELL

Genetic Regulatory Networks that count to 3

(2013) Malte Lehmann et al.   JOURNAL OF THEORETICAL BIOLOGY

The Utility of Paradoxical Components in Biological Circuits

(2013) Yuval Hart et al.   MOLECULAR CELL

Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation

(2013) Kazuhiro Aoki et al.   MOLECULAR CELL

Functional Roles of Pulsing in Genetic Circuits

(2013) J. H. Levine et al.   SCIENCE

Oscillatory Control of Factors Determining Multipotency and Fate in Mouse Neural Progenitors

(2013) I. Imayoshi et al.   SCIENCE

Activation of Ras/PI3K/ERK Pathway Induces c-Myc Stabilization to Upregulate Argininosuccinate Synthetase, Leading to Arginine Deiminase Resistance in Melanoma Cells

(2012) W.-B. Tsai et al.   CANCER RESEARCH

Histone Demethylase KDM5B Collaborates with TFAP2C and Myc To Repress the Cell Cycle Inhibitor p21cip (CDKN1A)

(2012) P.-P. Wong et al.   MOLECULAR AND CELLULAR BIOLOGY

Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals

(2012) John G. Albeck et al.   MOLECULAR CELL

p53 Dynamics Control Cell Fate

(2012) J. E. Purvis et al.   SCIENCE

Impulse Control: Temporal Dynamics in Gene Transcription

(2011) Nir Yosef et al.   CELL

The c-MYC-AP4-p21 cascade

(2011) Peter Jung et al.   CELL CYCLE

Stimulus-dependent dynamics of p53 in single cells

(2011) E. Batchelor et al.   Molecular Systems Biology

Single-cell NF-κB dynamics reveal digital activation and analogue information processing

(2010) Savaş Tay et al.   NATURE

A synchronized quorum of genetic clocks

(2010) Tal Danino et al.   NATURE

Simple molecular networks that respond optimally to time-periodic stimulation

(2009) Axel Cournac et al.   BMC Systems Biology

Defining Network Topologies that Can Achieve Biochemical Adaptation

(2009) Wenzhe Ma et al.   CELL

NFIL3 and cAMP Response Element-Binding Protein Form a Transcriptional Feedforward Loop that Controls Neuronal Regeneration-Associated Gene Expression

(2009) H. D. MacGillavry et al.   JOURNAL OF NEUROSCIENCE

The Incoherent Feedforward Loop Can Provide Fold-Change Detection in Gene Regulation

(2009) Lea Goentoro et al.   MOLECULAR CELL

Protein sequestration generates a flexible ultrasensitive response in a genetic network

(2009) Nicolas E Buchler et al.   Molecular Systems Biology

An externally tunable bacterial band-pass filter

(2009) T. Sohka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pulsatile Stimulation Determines Timing and Specificity of NF- B-Dependent Transcription

(2009) L. Ashall et al.   SCIENCE

Synthetic Gene Networks That Count

(2009) A. E. Friedland et al.   SCIENCE

The biphasic behavior of incoherent feed-forward loops in biomolecular regulatory networks

(2008) Dongsan Kim et al.   BIOESSAYS

The dark side of a tumor suppressor: anti-apoptotic p53

(2008) R U Jänicke et al.   CELL DEATH AND DIFFERENTIATION

Molecular Titration and Ultrasensitivity in Regulatory Networks

(2008) Nicolas E. Buchler et al.   JOURNAL OF MOLECULAR BIOLOGY

A fast, robust and tunable synthetic gene oscillator

(2008) Jesse Stricker et al.   NATURE

Design principles of biochemical oscillators

(2008) Béla Novák et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sensing and Integration of Erk and PI3K Signals by Myc

(2008) Tae Lee et al.   PLoS Computational Biology