Large-Scale Off-Target Identification Using Fast and Accurate Dual Regularized One-Class Collaborative Filtering and Its Application to Drug Repurposing
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Large-Scale Off-Target Identification Using Fast and Accurate Dual Regularized One-Class Collaborative Filtering and Its Application to Drug Repurposing
Authors
Keywords
Cancer treatment, Drug-drug interactions, Algorithms, Drug discovery, Drug interactions, Forecasting, Tyrosine kinase inhibitors, Drug screening
Journal
PLoS Computational Biology
Volume 12, Issue 10, Pages e1005135
Publisher
Public Library of Science (PLoS)
Online
2016-10-08
DOI
10.1371/journal.pcbi.1005135
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Feasibility of Active Machine Learning for Multiclass Compound Classification
- (2016) Tobias Lang et al. Journal of Chemical Information and Modeling
- Scientists in the dark after French clinical trial proves fatal
- (2016) Declan Butler et al. NATURE
- Neighborhood Regularized Logistic Matrix Factorization for Drug-Target Interaction Prediction
- (2016) Yong Liu et al. PLoS Computational Biology
- Improving compound–protein interaction prediction by building up highly credible negative samples
- (2015) Hui Liu et al. BIOINFORMATICS
- Unmasking Determinants of Specificity in the Human Kinome
- (2015) Pau Creixell et al. CELL
- Deep Neural Nets as a Method for Quantitative Structure–Activity Relationships
- (2015) Junshui Ma et al. Journal of Chemical Information and Modeling
- Why is Tanimoto index an appropriate choice for fingerprint-based similarity calculations?
- (2015) Dávid Bajusz et al. Journal of Cheminformatics
- Albumin nanoparticles increase the anticancer efficacy of albendazole in ovarian cancer xenograft model
- (2015) Lubna Noorani et al. JOURNAL OF NANOBIOTECHNOLOGY
- CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide
- (2015) Richard E. Kast et al. Oncotarget
- Activity cliffs in drug discovery: Dr Jekyll or Mr Hyde?
- (2014) Maykel Cruz-Monteagudo et al. DRUG DISCOVERY TODAY
- The Comparative Toxicogenomics Database's 10th year anniversary: update 2015
- (2014) Allan Peter Davis et al. NUCLEIC ACIDS RESEARCH
- Anticancer Effects of Niclosamide in Human Glioblastoma
- (2013) A. Wieland et al. CLINICAL CANCER RESEARCH
- Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer
- (2013) Peter Nygren et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- In Silico Target Predictions: Defining a Benchmarking Data Set and Comparison of Performance of the Multiclass Naïve Bayes and Parzen-Rosenblatt Window
- (2013) Alexios Koutsoukas et al. Journal of Chemical Information and Modeling
- Anti-cancer mechanisms of clinically acceptable colchicine concentrations on hepatocellular carcinoma
- (2013) Zu-Yau Lin et al. LIFE SCIENCES
- A pharmacological organization of G protein–coupled receptors
- (2013) Henry Lin et al. NATURE METHODS
- Predicting Drug-Target Interactions for New Drug Compounds Using a Weighted Nearest Neighbor Profile
- (2013) Twan van Laarhoven et al. PLoS One
- Predicting drug-target interactions from chemical and genomic kernels using Bayesian matrix factorization
- (2012) M. Gonen BIOINFORMATICS
- Raloxifene attenuates Pseudomonas aeruginosa pyocyanin production and virulence
- (2012) Shannan J. Ho Sui et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- ZINC: A Free Tool to Discover Chemistry for Biology
- (2012) John J. Irwin et al. Journal of Chemical Information and Modeling
- Reducing safety-related drug attrition: the use of in vitro pharmacological profiling
- (2012) Joanne Bowes et al. NATURE REVIEWS DRUG DISCOVERY
- Novel Computational Approaches to Polypharmacology as a Means to Define Responses to Individual Drugs
- (2011) Lei Xie et al. Annual Review of Pharmacology and Toxicology
- Gaussian interaction profile kernels for predicting drug–target interaction
- (2011) Twan van Laarhoven et al. BIOINFORMATICS
- Drug Discovery Using Chemical Systems Biology: Weak Inhibition of Multiple Kinases May Contribute to the Anti-Cancer Effect of Nelfinavir
- (2011) Li Xie et al. PLoS Computational Biology
- A Multidimensional Strategy to Detect Polypharmacological Targets in the Absence of Structural and Sequence Homology
- (2010) Jacob D. Durrant et al. PLoS Computational Biology
- BLAST+: architecture and applications
- (2009) Christiam Camacho et al. BMC BIOINFORMATICS
- Drug Discovery Using Chemical Systems Biology: Repositioning the Safe Medicine Comtan to Treat Multi-Drug and Extensively Drug Resistant Tuberculosis
- (2009) Sarah L. Kinnings et al. PLoS Computational Biology
- Drug Discovery Using Chemical Systems Biology: Identification of the Protein-Ligand Binding Network To Explain the Side Effects of CETP Inhibitors
- (2009) Li Xie et al. PLoS Computational Biology
- Microtubule assembly dynamics: An attractive target for anticancer drugs
- (2008) Parminder Singh et al. IUBMB LIFE
- Virtual Screening System for Finding Structurally Diverse Hits by Active Learning
- (2008) Yukiko Fujiwara et al. Journal of Chemical Information and Modeling
- Detecting evolutionary relationships across existing fold space, using sequence order-independent profile-profile alignments
- (2008) L. Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More