Ultraviolet Radiation on the Skin: A Painful Experience?

UV radiation induces CXCL5 expression in human skin

(2015) Olga Reichert et al.   EXPERIMENTAL DERMATOLOGY

Neuroendocrine Role for VGF

(2015) Jo E. Lewis et al.   Frontiers in Endocrinology

Objective validation of central sensitization in the rat UVB and heat rekindling model

(2014) N.S. Weerasinghe et al.   EUROPEAN JOURNAL OF PAIN

Emerging drugs for neuropathic pain

(2014) Ian Gilron et al.   EXPERT OPINION ON EMERGING DRUGS

New investigational drugs for the treatment of neuropathic pain

(2014) Kinga Sałat et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Targeting angiotensin II type 2 receptor pathways to treat neuropathic pain and inflammatory pain

(2014) Maree T Smith et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Genome-Wide Transcriptional Profiling of Skin and Dorsal Root Ganglia after Ultraviolet-B-Induced Inflammation

(2014) John M. Dawes et al.   PLoS One

Targeting novel peripheral mediators for the treatment of chronic pain

(2013) N Richards et al.   BRITISH JOURNAL OF ANAESTHESIA

Spatial Sensory Organization and Body Representation in Pain Perception

(2013) Patrick Haggard et al.   CURRENT BIOLOGY

Photoaging

(2013) Barbara A. Gilchrest   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Nerve growth factor: an update on the science and therapy

(2013) M.F. Seidel et al.   OSTEOARTHRITIS AND CARTILAGE

The pattern and time course of somatosensory changes in the human UVB sunburn model reveal the presence of peripheral and central sensitization

(2013) Burkhard Gustorff et al.   PAIN

Synthesis of Lipid Mediators during UVB-Induced Inflammatory Hyperalgesia in Rats and Mice

(2013) Marco Sisignano et al.   PLoS One

UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling

(2013) Carlene Moore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An oral TRPV1 antagonist attenuates laser radiant-heat-evoked potentials and pain ratings from UVB-inflamed and normal skin

(2012) Klaus Schaffler et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

High frequency electrical stimulation concurrently induces central sensitization and ipsilateral inhibitory pain modulation

(2012) L. Vo et al.   EUROPEAN JOURNAL OF PAIN

Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects

(2012) Eef Hoeben et al.   PAIN

Effects of ultraviolet radiation, visible light, and infrared radiation on erythema and pigmentation: a review

(2012) Lindsay R. Sklar et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Antagonism of Nerve Growth Factor-TrkA Signaling and the Relief of Pain

(2011) Patrick W. Mantyh et al.   ANESTHESIOLOGY

Dose response of tramadol and its combination with paracetamol in UVB induced hyperalgesia

(2011) C.M. Ortner et al.   EUROPEAN JOURNAL OF PAIN

Antihyperalgesic efficacy of 5% lidocaine medicated plaster in capsaicin and sunburn pain models – two randomized, double-blinded, placebo-controlled crossover trials in healthy volunteers

(2011) Burkhard Gustorff et al.   EXPERT OPINION ON PHARMACOTHERAPY

Sensing hot and cold with TRP channels

(2011) William C. Wetsel   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Distribution and Expression of Non-Neuronal Transient Receptor Potential (TRPV) Ion Channels in Rosacea

(2011) Mathias Sulk et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Interferon-γ links ultraviolet radiation to melanomagenesis in mice

(2011) M. Raza Zaidi et al.   NATURE

Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site

(2011) Andrés Nieto-Posadas et al.   Nature Chemical Biology

Ultraviolet B-induced inflammation in the rat: A model of secondary hyperalgesia?

(2011) Emily K. Davies et al.   PAIN

In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization

(2011) Anthony P. Ford   Purinergic Signalling

CXCL5 Mediates UVB Irradiation-Induced Pain

(2011) J. M. Dawes et al.   Science Translational Medicine

New molecules for the treatment of pain

(2011) Sebastian Heinzmann et al.   Current Opinion in Supportive and Palliative Care

Placebo controlled, crossover validation study of oral ibuprofen and topical hydrocortisone-21-acetate for a model of ultraviolet B radiation (UVR)-induced pain and inflammation

(2011) Matthias Rother et al.   Journal of Pain Research

Effects of Intrathecal Ketorolac on Human Experimental Pain

(2010) James C. Eisenach et al.   ANESTHESIOLOGY

Effect of transdermal opioids in experimentally induced superficial, deep and hyperalgesic pain

(2010) T Andresen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents

(2010) Amol M. Patwardhan et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuronal circuitry for pain processing in the dorsal horn

(2010) Andrew J. Todd   NATURE REVIEWS NEUROSCIENCE

Synaptic Plasticity and Pain: Role of Ionotropic Glutamate Receptors

(2010) Max Larsson et al.   NEUROSCIENTIST

Ultraviolet-B-induced mechanical hyperalgesia: A role for peripheral sensitisation

(2010) Thomas Bishop et al.   PAIN

Central sensitization: Implications for the diagnosis and treatment of pain

(2010) Clifford J. Woolf   PAIN

Causes and Consequences of Inadequate Management of Acute Pain

(2010) Raymond Sinatra   PAIN MEDICINE

How Sunlight Causes Melanoma

(2010) Lilit Garibyan et al.   Current Oncology Reports

Cytokine Signaling Mediates UV-Induced Nociceptive Sensitization in Drosophila Larvae

(2009) Daniel T. Babcock et al.   CURRENT BIOLOGY

Light, including ultraviolet

(2009) Emanual Maverakis et al.   JOURNAL OF AUTOIMMUNITY

Proteomic Analysis Uncovers Novel Actions of the Neurosecretory Protein VGF in Nociceptive Processing

(2009) M. S. Riedl et al.   JOURNAL OF NEUROSCIENCE

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity

(2009) Alban Latremoliere et al.   JOURNAL OF PAIN

Solar ultraviolet radiation and skin cancer

(2009) C. Young   OCCUPATIONAL MEDICINE-OXFORD

Delayed ultraviolet erythema not suppressed by oral prednisolone: a randomized crossover study

(2009) F. M. Muller et al.   PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE

Ultraviolet-B induced inflammation of human skin: Characterisation and comparison with traditional models of hyperlagesia

(2008) Thomas Bishop et al.   EUROPEAN JOURNAL OF PAIN

Origins, Actions and Dynamic Expression Patterns of the Neuropeptide VGF in Rat Peripheral and Central Sensory Neurones Following Peripheral Nerve Injury

(2008) Andrew Moss et al.   Molecular Pain

Cytokine profile in human skin in response to experimental inflammation, noxious stimulation, and administration of a COX-inhibitor: A microdialysis study

(2008) M. S. Angst et al.   PAIN

Keine Wirkung bei topischer Applikation von Morphin- und Buprenorphingel im Sonnenbrandmodell

(2008) J. Draxler et al.   SCHMERZ

Ultra violet-induced localized inflammatory hyperalgesia in awake rats and the role of sensory and sympathetic innervation of the skin

(2007) Nayef E. Saadé et al.   BRAIN BEHAVIOR AND IMMUNITY