Glial Pathology in Bipolar Disorder: Potential Therapeutic Implications

Monocyte activation, brain-derived neurotrophic factor (BDNF), and S100B in bipolar offspring: a follow-up study from adolescence into adulthood

(2014) Esther Mesman et al.   BIPOLAR DISORDERS

Improvement of functional recovery by chronic metformin treatment is associated with enhanced alternative activation of microglia/macrophages and increased angiogenesis and neurogenesis following experimental stroke

(2014) Qin Jin et al.   BRAIN BEHAVIOR AND IMMUNITY

Aquaporin-4 Knockout Exacerbates Corticosterone-Induced Depression by Inhibiting Astrocyte Function and Hippocampal Neurogenesis

(2014) Hui Kong et al.   CNS Neuroscience & Therapeutics

Astrocytic JWA Expression is Essential to Dopaminergic Neuron Survival in the Pathogenesis of Parkinson's Disease

(2014) Shu-Han Miao et al.   CNS Neuroscience & Therapeutics

Elevation of cerebrospinal fluid interleukin-1β in bipolar disorder

(2014) Johan Söderlund et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Neuropathological and neuromorphometric abnormalities in bipolar disorder: View from the medial prefrontal cortical network

(2014) Jonathan B. Savitz et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Glia and immune cell signaling in bipolar disorder: insights from neuropharmacology and molecular imaging to clinical application

(2014) C C Watkins et al.   Translational Psychiatry

Potential Drugs Targeting Microglia: Current Knowledge and Future Prospects

(2013) Parakalan Rangarajan et al.   CNS & Neurological Disorders-Drug Targets

Quercetin Improves Behavioral Deficiencies, Restores Astrocytes and Microglia, and Reduces Serotonin Metabolism in 3-Nitropropionic Acid-Induced Rat Model of Huntington's Disease

(2013) Joy Chakraborty et al.   CNS Neuroscience & Therapeutics

Serum S100B Represents a New Biomarker for Mood Disorders

(2013) Matthias Schroeter et al.   CURRENT DRUG TARGETS

Valproic acid induces astrocyte-dependent neurite outgrowth from cultured rat primary cortical neuron via modulation of tPA/PAI-1 activity

(2013) Kyu Suk Cho et al.   GLIA

S100B-immunopositive astrocytes and oligodendrocytes in the hippocampus are differentially afflicted in unipolar and bipolar depression: A postmortem study

(2013) Tomasz Gos et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Cell-Specific mRNA Alterations in Na+, K+-ATPase α and β Isoforms and FXYD in Mice Treated Chronically with Carbamazepine, an Anti-Bipolar Drug

(2013) Baoman Li et al.   NEUROCHEMICAL RESEARCH

Introduction - Bipolar Illness: Current Understanding and Future Perspectives

(2012) Konstantinos N. Fountoulakis   CNS Neuroscience & Therapeutics

Is bipolar disorder an inflammatory condition? The relevance of microglial activation

(2012) Laura Stertz et al.   CURRENT OPINION IN PSYCHIATRY

Microglia as modulators of cognition and neuropsychiatric disorders

(2012) Thomas Blank et al.   GLIA

Cytokines in bipolar disorder: A systematic review and meta-analysis

(2012) Klaus Munkholm et al.   JOURNAL OF AFFECTIVE DISORDERS

Chronic Treatment with Anti-bipolar Drugs Causes Intracellular Alkalinization in Astrocytes, Altering Their Functions

(2012) Dan Song et al.   NEUROCHEMICAL RESEARCH

Valproic acid mediates the synaptic excitatory/inhibitory balance through astrocytes — A preliminary study

(2012) Chao-Chuan Wang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Four mood stabilizers commonly induce FEZ1 expression in human astrocytes

(2011) Zhiqian Yu et al.   BIPOLAR DISORDERS

The activation of monocyte and T cell networks in patients with bipolar disorder

(2011) Roosmarijn C. Drexhage et al.   BRAIN BEHAVIOR AND IMMUNITY

State of the Art: Treatment of Bipolar Disorders

(2011) Emanuel Severus et al.   CNS Neuroscience & Therapeutics

Molecular signals of plasticity at the tetrapartite synapse

(2011) Alexander Dityatev et al.   CURRENT OPINION IN NEUROBIOLOGY

Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia

(2011) Sigrun Hope et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Does conventional anti-bipolar and antidepressant drug therapy reduce NMDA-mediated neuronal excitation by downregulating astrocytic GluK2 function?

(2011) Liang Peng et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Manic episodes are associated with grey matter volume reduction - a voxel-based morphometry brain analysis

(2010) C. J. Ekman et al.   ACTA PSYCHIATRICA SCANDINAVICA

Histone Deacetylases and Mood Disorders: Epigenetic Programming in Gene-Environment Interactions

(2010) Rodrigo Machado-Vieira et al.   CNS Neuroscience & Therapeutics

Regulated exocytosis in astrocytic signal integration

(2010) Vladimir Parpura et al.   NEUROCHEMISTRY INTERNATIONAL

Increased plasma levels of brain-derived neurotrophic factor in patients with long-term bipolar disorder

(2010) Izabela Guimarães Barbosa et al.   NEUROSCIENCE LETTERS

Potential Mechanisms Involved in the Prevention of Neurodegenerative Diseases by Lithium

(2009) Antoni Camins et al.   CNS Neuroscience & Therapeutics

Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients

(2009) J S Rao et al.   MOLECULAR PSYCHIATRY

Extracellular matrix in plasticity and epileptogenesis

(2009) Alexander Dityatev et al.   Neuron Glia Biology

Down-regulation of GluK2 kainate receptor expression by chronic treatment with mood-stabilizing anti-convulsants or lithium in cultured astrocytes and brain, but not in neurons

(2009) Baoman Li et al.   NEUROPHARMACOLOGY

Kainate receptors: Pharmacology, function and therapeutic potential

(2008) David E. Jane et al.   NEUROPHARMACOLOGY

Mitochondrially Mediated Plasticity in the Pathophysiology and Treatment of Bipolar Disorder

(2008) Jorge A Quiroz et al.   NEUROPSYCHOPHARMACOLOGY

Lithium: Bipolar disorder and neurodegenerative diseases Possible cellular mechanisms of the therapeutic effects of lithium

(2008) Frederic Marmol   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Astrocytic alkalinization by therapeutically relevant lithium concentrations: implications for myo-inositol depletion

(2008) Dan Song et al.   PSYCHOPHARMACOLOGY