Review
Otorhinolaryngology
Krishnakumar Thankappan, Sujha Subramanian, Deepak Balasubramanian, Moni Abraham Kuriakose, Rengaswamy Sankaranarayanan, Subramania Iyer
Summary: Oral cancer screening has been found to be a cost-effective strategy, especially in opportunistic settings and high-risk populations. The results are sensitive to cost and effectiveness parameters, suggesting a need for further studies with more accurate estimates. Heterogeneity in the studies limits comparison and generalization.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Review
Dentistry, Oral Surgery & Medicine
S. Warnakulasuriya, A. R. Kerr
Summary: Oral cancer is a significant public health issue, affecting young individuals with poor public awareness. Early detection through visual inspection of premalignant lesions before oral cancer develops can reduce mortality. Screening for high-risk groups is cost-effective, but population-based screening lacks sufficient evidence.
JOURNAL OF DENTAL RESEARCH
(2021)
Article
Oncology
Jos B. Poell, Leon J. Wils, Arjen Brink, Ralf Dietrich, Christine Krieg, Eunike Velleuer, Ilkay Evren, Elisabeth R. Brouns, Jan G. de Visscher, Elisabeth Bloemena, Bauke Ylstra, Ruud H. Brakenhoff
Summary: This study developed a noninvasive genetic assay to detect genetically altered fields in the oral cavity. The assay demonstrated high accuracy and predicted the development of oral squamous cell carcinoma in high-risk individuals. This method can be used for cancer screening in high-risk populations and to map the extent of lesions beyond what is visible.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Oncology
Takamichi Morikawa, Takahiko Shibahara, Masayuki Takano, Masashi Iwamoto, Takashi Takaki, Kiyohiro Kasahara, Takeshi Nomura, Nobuo Takano, Akira Katakura
Summary: The study shows that there is no significant difference in oral cancer detection rates between countermeasure and opportunistic screenings, but opportunistic screening is more effective in terms of the number of participants, close examination rate, and detection rate of oral potentially malignant disorders.
Article
Oncology
Li C. Cheung, Kunnambath Ramadas, Richard Muwonge, Hormuzd A. Katki, Gigi Thomas, Barry Graubard, Partha Basu, Rengaswamy Sankaranarayanan, Thara Somanathan, Anil K. Chaturvedi
Summary: The study demonstrated the potential of risk-based oral cancer screening to enhance screening efficiency. Oral cancer screening significantly reduced oral cancer mortality rates, especially in high-risk individuals.
JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Chemistry, Physical
Zuohui Xiao, Chenyan Huang, Shengjie Jiang, Xiangyu Kong, Yunfei Teng, Bo Niu, CongCong Zhu, Weiwen Xin, Xiaohui Chen, Liping Wen, Yan Wei, Xuliang Deng
Summary: An ultrasensitive and selective electrochemical liquid biopsy technique based on functionalized nano-channels is developed for oral cancer screening, allowing for the identification of trace amounts of cancer biomarkers in bio-fluids. Through antigen-antibody reactions and ion transport, this technique achieves high sensitivity and specificity in oral cancer detection.
Article
Oncology
Sama Rezasoltani, Hamid Asadzadeh Aghdaei, Seyedesomaye Jasemi, Maria Gazouli, Nikolas Dovrolis, Amir Sadeghi, Hartmut Schlueter, Mohammad Reza Zali, Leonardo Antonio Sechi, Mohammad Mehdi Feizabadi
Summary: This study conducted a comprehensive analysis of the microbiome in saliva and stool samples of colorectal cancer (CRC) patients in Iran, comparing them with healthy controls. The results showed distinct clustering of microbial genera in CRC patients and healthy controls, indicating unique microbial signatures in both conditions. However, further investigation is needed to understand the roles of microbiota in CRC and healthy individuals.
Editorial Material
Oncology
Anil K. D'Cruz, Richa Vaish
Summary: The Kerala Oral Cancer Screening Trial did not show a decrease in cancer-related mortality, but a recent reanalysis of the data revealed important lessons learned and the advantages of using a novel risk-based approach to screening.
NATURE REVIEWS CLINICAL ONCOLOGY
(2021)
Article
Medicine, General & Internal
M. Patricia Rivera, Danielle D. Durham, Jason M. Long, Pasangi Perera, Lindsay Lane, Derek Lamb, Eman Metwally, Louise M. Henderson
Summary: This prospective cohort study investigated the rates and factors associated with recommended follow-up after a positive lung cancer screening examination using the Lung-RADS category. The study found that adherence to recommended follow-up was low overall but improved for nodules with a higher suspicion of cancer and after extending the follow-up timeline.
Article
Oncology
John D. Cramer, Jordan Grauer
Summary: The study findings suggest that targeting oral cancer screening at high-risk populations can significantly reduce oral cancer mortality and improve screening efficiency. Future screening trials in high-risk individuals may be considered to clarify the role of oral cancer screening in the US.
Article
Oncology
Sainan Guan, Ronghua Yan, Xiaomin Chen, Weiqiang Chen, Xi Zhou, Minghui Zhou, Zhengneng Xie, Wen Tan, Yongyan He, Juan Fu, Fan Yuan, Erjiao Xu
Summary: This study retrospectively investigated the use of oral contrast-enhanced ultrasonography (O-CEUS) in assessing gastric wall thickness for gastric cancer (GC) screening and established screening strategies based on risk stratification. The results showed that O-CEUS is a convenient, economical, safe, and noninvasive method for GC screening. Measuring gastric wall thickness helps predict the risk of GC occurrence.
FRONTIERS IN ONCOLOGY
(2023)
Article
Multidisciplinary Sciences
Zhu Changkun, Ghose Bishwajit, Lu Ji, Shangfeng Tang
Summary: This study provides important insights into the current scenario of seeking cancer screening services among women in India. The findings suggest that older age, urban residence, higher education, employment, health insurance ownership, exposure to electronic media, higher household wealth, and better healthcare autonomy are associated with a higher uptake of cancer screening services. Additionally, the strength of these associations varies between urban and rural residents, indicating the need for region-specific intervention strategies.
Article
Public, Environmental & Occupational Health
Chien-Ching Li, Alicia K. Matthews, Yu-Hsiang Kao, Wei-Ting Lin, Jad Bahhur, Linda Dowling
Summary: The study found that access to care factors have an independent impact on the uptake of LDCT lung cancer screening. Individuals with Medicaid insurance and living within the AMC service area had higher odds of receiving LDCT screening, while those with Medicare insurance and out-of-pocket payments had lower odds of screening completion.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Multidisciplinary Sciences
Tran Thu Ngan, Chris Jenkins, Hoang Van Minh, Michael Donnelly, Ciaran O'Neill
Summary: This study examined current breast cancer screening practices among Vietnamese women and identified factors associated with the uptake of clinical breast examination (CBE). The study found low levels of awareness about breast cancer, with CBE being the most common screening modality. It also revealed that urban residents were more likely to receive mammography compared to rural residents. However, the uptake of CBE was not associated with sociodemographic characteristics, but rather with breast cancer knowledge, perceived susceptibility, and perceived barriers to accessing CBE.
Article
Biochemical Research Methods
Bofan Song, Sumsum Sunny, Shaobai Li, Keerthi Gurushanth, Pramila Mendonca, Nirza Mukhia, Sanjana Patrick, Shubha Gurudath, Subhashini Raghavan, Tsusennaro Imchen, Shirley Leivon, Trupti Kolur, Vivek Shetty, Vidya Bushan, Rohan Ramesh, Natzem Lima, Vijay Pillai, Petra Wilder-Smith, Alben Sigamani, Amritha Suresh, Moni Kuriakose, Praveen Birur, Rongguang Liang
Summary: This study developed a mobile-based dual-mode image classification method and Android application for oral cancer detection. The method showed high accuracy and fast processing speed on a cost-effective smartphone platform, making it suitable for screening in low-resource settings.
JOURNAL OF BIOMEDICAL OPTICS
(2021)
