Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders

Lamin Dysfunction Mediates Neurodegeneration in Tauopathies

(2016) Bess Frost et al.   CURRENT BIOLOGY

Genome-wide epistatic expression quantitative trait loci discovery in four human tissues reveals the importance of local chromosomal interactions governing gene expression

(2015) Darren J Fitzpatrick et al.   BMC GENOMICS

Localization and regulation of PML bodies in the adult mouse brain

(2015) Małgorzata H. Hall et al.   Brain Structure & Function

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

(2015) Ya Guo et al.   CELL

Chromatin Fibers Are Formed by Heterogeneous Groups of Nucleosomes In Vivo

(2015) Maria Aurelia Ricci et al.   CELL

Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes

(2015) Ram Madabhushi et al.   CELL

The Mendelian disorders of the epigenetic machinery

(2015) Hans Tomas Bjornsson   GENOME RESEARCH

Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice

(2015) M. Achour et al.   HUMAN MOLECULAR GENETICS

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation

(2015) J. Fraser et al.   Molecular Systems Biology

Chromatin architecture reorganization during stem cell differentiation

(2015) Jesse R. Dixon et al.   NATURE

Stimulus-specific combinatorial functionality of neuronal c-fos enhancers

(2015) Jae-Yeol Joo et al.   NATURE NEUROSCIENCE

The contribution of cohesin-SA1 to gene expression and chromatin architecture in two murine tissues

(2015) Ana Cuadrado et al.   NUCLEIC ACIDS RESEARCH

Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope

(2015) Shang-Yi A. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A matter of scale: how emerging technologies are redefining our view of chromosome architecture

(2015) Diego I. Cattoni et al.   TRENDS IN GENETICS

Unraveling the 3D genome: genomics tools for multiscale exploration

(2015) Viviana I. Risca et al.   TRENDS IN GENETICS

Role of FKBP5 in emotion processing: results on amygdala activity, connectivity and volume

(2014) Nathalie E. Holz et al.   Brain Structure & Function

Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes

(2014) Jill M. Dowen et al.   CELL

SIRPB1copy-number polymorphism as candidate quantitative trait locus for impulsive-disinhibited personality

(2014) M. Laplana et al.   GENES BRAIN AND BEHAVIOR

Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon

(2014) D. Spieler et al.   GENOME RESEARCH

Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior

(2014) Jean-Ha Baek et al.   HUMAN MOLECULAR GENETICS

Dual Effect of CTCF Loss on Neuroprogenitor Differentiation and Survival

(2014) L. A. Watson et al.   JOURNAL OF NEUROSCIENCE

Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2

(2014) John M. Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Enhancer Function: Mechanistic and Genome-Wide Insights Come Together

(2014) Jennifer L. Plank et al.   MOLECULAR CELL

Enhancer RNA Facilitates NELF Release from Immediate Early Genes

(2014) Katie Schaukowitch et al.   MOLECULAR CELL

Genome-wide identification and characterization of functional neuronal activity–dependent enhancers

(2014) Athar N Malik et al.   NATURE NEUROSCIENCE

Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors

(2014) Elizabeth A Heller et al.   NATURE NEUROSCIENCE

Conserved Higher-Order Chromatin Regulates NMDA Receptor Gene Expression and Cognition

(2014) Rahul Bharadwaj et al.   NEURON

Significance of higher-order chromatin architecture for neuronal function and dysfunction

(2014) Grzegorz M. Wilczynski   NEUROPHARMACOLOGY

Nuclear architecture as an epigenetic regulator of neural development and function

(2014) J.M. Alexander et al.   NEUROSCIENCE

Nucleolar Integrity Is Required for the Maintenance of Long-Term Synaptic Plasticity

(2014) Kim D. Allen et al.   PLoS One

Two ways to fold the genome during the cell cycle: insights obtained with chromosome conformation capture

(2014) Job Dekker   Epigenetics & Chromatin

Large-Scale Identification of Coregulated Enhancer Networks in the Adult Human Brain

(2014) Marit W. Vermunt et al.   Cell Reports

De Novo Mutations in the Genome Organizer CTCF Cause Intellectual Disability

(2013) Anne Gregor et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Control of Transcriptional Elongation

(2013) Hojoong Kwak et al.   Annual Review of Genetics

Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome

(2013) Silvia Remeseiro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Transcription Factor Binding in Human Cells Occurs in Dense Clusters Formed around Cohesin Anchor Sites

(2013) Jian Yan et al.   CELL

Interactome Maps of Mouse Gene Regulatory Domains Reveal Basic Principles of Transcriptional Regulation

(2013) Kyong-Rim Kieffer-Kwon et al.   CELL

Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment

(2013) Jennifer E. Phillips-Cremins et al.   CELL

Gene-environment interactions at theFKBP5locus: sensitive periods, mechanisms and pleiotropism

(2013) A. S. Zannas et al.   GENES BRAIN AND BEHAVIOR

Conserved Chromosome 2q31 Conformations Are Associated with Transcriptional Regulation of GAD1 GABA Synthesis Enzyme and Altered in Prefrontal Cortex of Subjects with Schizophrenia

(2013) R. Bharadwaj et al.   JOURNAL OF NEUROSCIENCE

Novel Higher-Order Epigenetic Regulation of the Bdnf Gene upon Seizures

(2013) A. Walczak et al.   JOURNAL OF NEUROSCIENCE

Chromatin connectivity maps reveal dynamic promoter–enhancer long-range associations

(2013) Yubo Zhang et al.   NATURE

The Emerging Field of Neuroepigenetics

(2013) J. David Sweatt   NEURON

The synaptic plasticity and memory hypothesis: encoding, storage and persistence

(2013) T. Takeuchi et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration

(2013) H.-J. Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells

(2013) I. I. Cisse et al.   SCIENCE

Binding of TFIIIC to SINE Elements Controls the Relocation of Activity-Dependent Neuronal Genes to Transcription Factories

(2013) Luca Crepaldi et al.   PLoS Genetics

DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina

(2012) Joseph M. Zullo et al.   CELL

Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation

(2012) Guoliang Li et al.   CELL

Transcription factories: genetic programming in three dimensions

(2012) Lucas Brandon Edelman et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

ATRX

(2012) Kajan Ratnakumar et al.   Epigenetics

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

CTCF Is Required for Neural Development and Stochastic Expression of Clustered Pcdh Genes in Neurons

(2012) Teruyoshi Hirayama et al.   Cell Reports

Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity

(2012) C S Weickert et al.   Translational Psychiatry

Nuclei of chicken neurons in tissues and three-dimensional cell cultures are organized into distinct radial zones

(2011) Doris Berchtold et al.   CHROMOSOME RESEARCH

MeCP2 Rett mutations affect large scale chromatin organization

(2011) Noopur Agarwal et al.   HUMAN MOLECULAR GENETICS

Purkinje Cell Degeneration inpcdMice Reveals Large Scale Chromatin Reorganization and Gene Silencing Linked to Defective DNA Repair

(2011) Fernando C. Baltanás et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death

(2011) Kuei-Hua Chang et al.   MOLECULAR BIOLOGY OF THE CELL

CTCF-mediated functional chromatin interactome in pluripotent cells

(2011) Lusy Handoko et al.   NATURE GENETICS

The proteomes of transcription factories containing RNA polymerases I, II or III

(2011) Svitlana Melnik et al.   NATURE METHODS

Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II

(2011) Ramendra N Saha et al.   NATURE NEUROSCIENCE

MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation

(2011) Malaika K. Singleton et al.   NEUROBIOLOGY OF DISEASE

The nucleoplasmic reticulum: form and function

(2011) Ashraf Malhas et al.   TRENDS IN CELL BIOLOGY

Activity-dependent calcium signaling and ERK-MAP kinases in neurons: A link to structural plasticity of the nucleus and gene transcription regulation

(2010) J. Simon Wiegert et al.   CELL CALCIUM

The transcriptional interactome: gene expression in 3D

(2010) Stefan Schoenfelder et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Setdb1 Histone Methyltransferase Regulates Mood-Related Behaviors and Expression of the NMDA Receptor Subunit NR2B

(2010) Y. Jiang et al.   JOURNAL OF NEUROSCIENCE

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

(2010) Daan Peric-Hupkes et al.   MOLECULAR CELL

Widespread transcription at neuronal activity-regulated enhancers

(2010) Tae-Kyung Kim et al.   NATURE

Mediator and cohesin connect gene expression and chromatin architecture

(2010) Michael H. Kagey et al.   NATURE

Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

(2009) Irina Solovei et al.   CELL

Murine hippocampal neurons expressing Fmr1 gene premutations show early developmental deficits and late degeneration

(2009) Y. Chen et al.   HUMAN MOLECULAR GENETICS

Synaptic Activity Induces Dramatic Changes in the Geometry of the Cell Nucleus: Interplay between Nuclear Structure, Histone H3 Phosphorylation, and Nuclear Calcium Signaling

(2009) M. Wittmann et al.   JOURNAL OF NEUROSCIENCE

Nuclear bodies in neurodegenerative disease

(2008) John Woulfe   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Analysis of protocadherin alpha gene enhancer polymorphism in bipolar disorder and schizophrenia

(2008) E PEDROSA et al.   SCHIZOPHRENIA RESEARCH

Chromatin and nuclear architecture in the nervous system

(2008) Takumi Takizawa et al.   TRENDS IN NEUROSCIENCES