Article
Medicine, General & Internal
Daniel Adrian Tartea, Mihaela Ionescu, Horia Octavian Manolea, Veronica Mercut, Eugenia Obadan, Marina Olimpia Amarascu, Petre Costin Marasescu, Luminita Daguci, Sanda Mihaela Popescu
Summary: The implementation of CAD-CAM systems in dentistry has had a significant impact on the development of dental implantology and implant-supported prosthetics. This paper presents a comparative study between custom CAD-CAM implant abutments and dental implant stock abutments, revealing significant differences in dimensions and angles. The use of custom abutments results in improved aesthetics, retention, and reduced risk of screw loosening or fracturing.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
P. Carosi, P. Cardelli, A. Laureti, A. Leggeri, C. Lorenzi
Summary: This study evaluates the clinical and radiological performance of a novel dental implant positioned in anterior sockets and immediately loaded. The implant showed high survival and success rates, and minimal marginal bone loss.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2022)
Review
Chemistry, Physical
Luca Fiorillo, Marco Cicciu, Tolga Fikret Tozum, Matteo Saccucci, Cristiano Orlando, Giovanni Luca Romano, Cesare D'Amico, Gabriele Cervino
Summary: In recent years, implantology has made significant progress, with the development of new alloys, surfaces, and geometries. This review analyzed the clinical differences between zirconia and titanium implants and found no statistically significant differences in fixed or overdenture restorations. However, there were concerns about the rigidity and potential fracture of zirconia.
Article
Dentistry, Oral Surgery & Medicine
Edmara T. P. Bergamo, Tiago M. C. Bastos, Adolfo C. O. Lopes, Everardo N. S. de Araujo Junior, Paulo G. Coelho, Ernesto B. Benalcazar Jalkh, Abbas Zahoui, Estevam A. Bonfante
Summary: The study characterized the physicochemical and mechanical properties of a milled fiber-reinforced composite for implant-supported fixed dental prostheses. Results showed that FDPs fabricated with milled epoxy resin matrix reinforced with glass fibers demonstrated high probability of survival at 300N load, indicating good fatigue performance.
Article
Dentistry, Oral Surgery & Medicine
Arvin Shahbazi, Georg Feigl, Anton Sculean, Andras Grimm, Daniel Palkovics, Balint Molnar, Peter Windisch
Summary: The study investigated the vascular supply of the maxillary vestibule through macroscopic and radiographic methods, revealing the anatomical basis behind clinically documented phenomena related to oral and periodontal surgeries.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Engineering, Biomedical
Hanna-Riikka Rantamaa, Jari Kangas, Maarit Jordan, Helena Mehtonen, John Makela, Kimmo Ronkainen, Markku Turunen, Osku Sundqvist, Ismo Syrja, Jorma Jarnstedt, Roope Raisamo
Summary: This study evaluates the perception of professional users on the use of a virtual environment for dental implant planning. Direct interaction was preferred over indirect interaction, indicating the value of a three-dimensional environment for three-dimensional object manipulation.
INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY
(2022)
Article
Pharmacology & Pharmacy
Jianbin Guo, Pei-Wei Tsai, Xingsi Xue, Dong Wu, Qui Tran Van, Chanaka Nimantha Kaluarachchi, Hong Thi Dang, Nikhitha Chintha
Summary: The dental implant identification system is designed to assist dentists in identifying the implant manufacturer from X-ray images, reducing their burden and improving system performance.
FRONTIERS IN PHARMACOLOGY
(2022)
Editorial Material
Medicine, General & Internal
Joao Paulo Mendes Tribst, Arie Werner, Erik J. Blom
Summary: Concerns have arisen recently about potential deformations and fractures of titanium implants, despite their widespread use in orthopedic and dental surgeries. In a recent clinical case, a titanium implant fractured after successful osseointegration, even without significant trauma or excessive external force. Factors including design flaws, material fatigue, and biomechanical stress during functional loading contribute to such fractures. This raises concerns about the long-term durability and reliability of titanium implants, especially in high-stress areas.
Article
Chemistry, Physical
Jefferson David Melo de Matos, Guilherme da Rocha Scalzer Lopes, Daher Antonio Queiroz, Andre Luiz Jesus Pereira, Mario Alexandre Coelho Sinhoreti, Nathalia de Carvalho Ramos, Vinicius Lino, Flavio Rosa de Oliveira, Alexandre Luiz Souto Borges, Marco Antonio Bottino
Summary: The present study evaluated the biomechanical behavior of PEEK abutments with different heights on single titanium implants. The results showed that PEEK abutments can be indicated with caution for implant-supported rehabilitation and may be suitable as temporary rehabilitation.
Article
Chemistry, Multidisciplinary
Luminita Oancea, Eugenia Panaitescu, Mihai Burlibasa, Catalin Gagiu
Summary: This study investigates the preferences and perspectives of prosthodontic specialists and dental technicians regarding materials, protocols, and designs for fixed prosthesis with implant support. The findings show differences and similarities between the two groups, with years of experience being correlated with the number of restorations and impression techniques. The study emphasizes the need for standardized education and training for prosthodontic specialists and technicians in Romania.
APPLIED SCIENCES-BASEL
(2022)
Article
Engineering, Biomedical
Baixuan Yang, Ainara Irastorza-Landa, Peter Heuberger, Heidi-Lynn Ploeg
Summary: This study proposed an analytical model to improve the understanding of the main factors influencing dental implant insertion torque. The model differentiated between different implant types and effectively represented the effects of various factors.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Joan Takamoli, Andres Pascual, Josep Martinez-Amargant, Berta Garcia-Mur, Jose Nart, Cristina Valles
Summary: This study evaluated the early and late implant loss rates in a cohort of patients who received implant-supported restorative therapy in a university setting from 2001 to 2012. The results showed that the rate of early implant failure was 0.6% and late implant failure was 3.7% after an average follow-up of 8.2 years. Factors associated with late implant failure included age under 55, smoking history, and poor access to interproximal hygiene.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Medicine, General & Internal
Young-Gun Shin, Won-Tak Cho, Ho-Kyung Lim, Su-Hyun Hwang, Ji-Hyeon Bae, Gang-Ho Bae, Jeong-Yol Lee, Jung-Bo Huh
Summary: This study demonstrates that the one-piece micro-locking implant system offers a predictable treatment method with good clinical outcomes for patients. Although there were no significant differences between the two groups, the MLF group showed superior performance in terms of plaque index.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Nicolas Blanc-Sylvestre, Philippe Bouchard, Catherine Chaussain, Claire Bardet
Summary: Biomedical research relies on animal models to bridge the gap between laboratory experiments and clinical applications, with current trends emphasizing the replacement, reduction, and refinement of animal use. New development strategies are gradually shifting towards in vitro or biomaterial approaches, highlighting the importance of thoughtful selection of animal models based on research objectives.
Article
Multidisciplinary Sciences
Lingxiao Wang, Zhenhua Gao, Yucheng Su, Qian Liu, Yi Ge, Zhaochen Shan
Summary: This study compared and verified the osseointegration performance of a novel implant in vivo, showing that the novel implants could promote bone formation better than traditional implants, but further improvements are still needed in some aspects.
SCIENTIFIC REPORTS
(2021)
Article
Biotechnology & Applied Microbiology
Sedigheh Abedanzadeh, Zainab Moosavi-Movahedi, Nader Sheibani, Ali A. Moosavi-Movahedi
Summary: This passage introduces nanozymes as alternatives to natural enzymes in industrial, medical, and biological fields, with a focus on designing enzyme models based on supramolecular scaffolds and the importance of supramolecular chemistry in understanding enzyme mechanisms.
BIOCHEMICAL ENGINEERING JOURNAL
(2022)
Article
Cell Biology
Christine M. Sorenson, Mitra Farnoodian, Shoujian Wang, Yong-Seok Song, Soesiawati R. Darjatmoko, Arthur S. Polans, Nader Sheibani
Summary: This paper investigates the potential of using S1PR agonists to inhibit choroidal neovascularization. Through in vitro and in vivo experiments, it is confirmed that S1PR1 is the most abundantly expressed receptor in choroidal endothelial cells and S1PR agonists can significantly suppress choroidal neovascularization. These findings suggest a potential new application for S1PR agonists in the treatment of nAMD and other inflammation-related diseases.
Article
Dentistry, Oral Surgery & Medicine
Mohammad Ali Saghiri, Nader Sheibani, Toshihisa Kawai, Devyani Nath, Sahar Dadvand, Saeid B. Amini, Julia Vakhnovetsky, Steven M. Morgano
Summary: This study evaluated the effect of type 1 diabetes mellitus (T1DM) on the micro-hardness of tooth enamel and dentine in mice. The results showed that T1DM negatively affected the micro-hardness of enamel and dentine, with enamel being more negatively and rapidly affected.
ARCHIVES OF ORAL BIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Leila Khalili, Gholamreza Dehghan, Nader Sheibani, Alireza Khataee
Summary: The production of multifunctional lipid-polymer hybrid nanoparticles offers great opportunities for selective and efficient therapeutics delivery by combining the biomimetic behavior of liposomes and the advantages of polymers. Bio-modifications show immense potential in addressing the challenges of scaling up production and enhancing biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Cell Biology
Yong-Seok Song, Andrew J. Annalora, Craig B. Marcus, Colin R. Jefcoate, Christine M. Sorenson, Nader Sheibani
Summary: Cytochrome P450 1B1 plays an important role in maintaining retinal iron homeostasis. By modulating iron levels, it influences oxidative stress and the development of ocular diseases.
Article
Cell Biology
Ismail S. Zaitoun, Yong-Seok Song, Hammam B. Zaitoun, Christine M. Sorenson, Nader Sheibani
Summary: This study established methods for visualizing choroidal macrophages, mast cells, and vasculature in the eyes of albino and pigmented mice, and found similarities between mice and humans in the arterial circle around the optic nerve. Different structural patterns of choriocapillaris were also observed. The findings contribute to the understanding and potential therapeutic targeting of ocular diseases affecting the choroid.
Article
Biochemistry & Molecular Biology
Christine M. Sorenson, Yong-Seok Song, Shoujian Wang, Soesiawati R. Darjatmoko, Mohammad Ali Saghiri, Mahsa Ranji, Nader Sheibani
Summary: Branching morphogenesis is a crucial developmental process that plays a significant role in organogenesis. This study investigates the impact of Bim, a protein involved in apoptosis, on the branching of ureteric bud and retinal vasculature. The findings demonstrate that appropriate expression of Bim is essential for proper apoptosis and branching in both the kidney and eye. Lack of Bim expression leads to increased branching but also results in branching defects and other undesirable consequences.
Article
Biochemistry & Molecular Biology
Yong-Seok Song, Ismail S. Zaitoun, Shoujian Wang, Soesiawati R. Darjatmoko, Christine M. Sorenson, Nader Sheibani
Summary: CYP1B1 expression in the retina is crucial for maintaining cellular redox homeostasis. Its metabolism of 17β-estradiol affects iron metabolism and lipid peroxidation, leading to iron accumulation and oxidative stress.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Cell Biology
Yong-Seok Song, Nasim Jamali, Christine M. M. Sorenson, Nader Sheibani
Summary: The integrity of retinal endothelial cell (EC) is crucial for maintaining retinal blood barrier and proper vision. Vitamin D, mainly mediated through the vitamin D receptor (VDR), plays a protective role in EC function. However, little is known about the impact of vitamin D-VDR on retinal EC function and ocular angiogenesis and inflammation. In this study, using retinal EC from VDR-deficient mice, the authors found that VDR expression is essential for endothelial cell-cell and cell-matrix interactions, as well as proliferation, migration, and inflammatory response of retinal EC. Furthermore, VDR deficiency leads to down-regulation of endothelial nitric oxide synthetase, enhanced hepcidin expression, and increased intracellular iron levels, contributing to the altered angiogenic and inflammatory state of retinal EC.
Article
Environmental Sciences
Nesa Hamidian, Gholamreza Dehghan, Samaneh Rashtbari, Alireza Khataee, Mehdi Khoobi, Nader Sheibani
Summary: A magnetite/Gd3+/beta-cyclodextrin nanoplatform was prepared and used for the degradation of tetracycline. The nanoplatform showed higher peroxidase-mimic activity than natural enzymes. It was able to degrade tetracycline efficiently and could be reused.
Article
Endocrinology & Metabolism
Subramanian Dharmarajan, Casandra Carrillo, Zhonghua Qi, Jonathan M. Wilson, Anthony J. Baucum II, Christine M. Sorenson, Nader Sheibani, Teri L. Belecky-Adams
Summary: This study aimed to investigate the impact of chronic inflammation on the loss of pericytes in early diabetic retinopathy. The results showed that both type 1 and type 2 diabetes led to similar progression of retinal pericyte loss and gliosis. However, the expression of inflammatory factors differed between the two diabetes models, with peak expression occurring at different ages. Additionally, retinal vascular changes were more severe in the type 2 diabetes model. Chronic exposure of retinal pericytes to IFN gamma resulted in decreased PDGFR beta signaling and increased levels of active PKC delta and CC3, indicating increased pericyte apoptosis.
Article
Biochemistry & Molecular Biology
Michele C. Larsen, Catherine M. Rondelli, Ahmed Almeldin, Yong-Seok Song, Alhaji N'Jai, David L. Alexander, E. Camilla Forsberg, Nader Sheibani, Colin R. Jefcoate
Summary: This study reveals the regulation of bone marrow cells by polycyclic aromatic hydrocarbon (PAH) pollutants and microbiome products through the aryl hydrocarbon receptor (AhR). The absence of Cyp1b1 and activation of AhR by PAH result in similar gene stimulations in these cells. Specific sources of Cyp1b1 are found to be linked to AhR and an OLFR network to modulate BM inflammation through diverse microbiome products.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Meeting Abstract
Ophthalmology
Ismail Saleh Zaitoun, Yong-Seok Song, Mohamed El Ragaby, Christine M. Sorenson, Nader Sheibani
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Meeting Abstract
Ophthalmology
Yong-Seok Song, Ismail Zaitoun, Christine M. Sorenson, Nader Sheibani
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
Meeting Abstract
Ophthalmology
Collin Goebel, Ismail Zaitoun, Heather Potter, Nader Sheibani
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2022)
