Article
Neuroimaging
Donato Colella, Massimiliano Passaretti, Viviana Frantellizzi, Maria Silvia De Feo, Antonio Cannavacciuolo, Luca Angelini, Daniele Birreci, Davide Costa, Giulia Paparella, Andrea Guerra, Giuseppe De Vincentis, Alfredo Berardelli, Matteo Bologna
Summary: This research investigated the correlation between basal ganglia dopaminergic neurotransmission and finger movements abnormalities in patients with essential tremor (ET) and Parkinson's disease (PD). The findings showed that ET patients had slower finger tapping and normal radiotracer uptake levels in the striatum, while PD patients had reduced uptake. There was also a connection between radiotracer uptake and movement velocity during finger tapping in both patient groups.
NEUROIMAGE-CLINICAL
(2023)
Article
Chemistry, Analytical
Asma Channa, Rares-Cristian Ifrim, Decebal Popescu, Nirvana Popescu
Summary: Parkinson's disease patients commonly experience motor symptoms such as tremor and bradykinesia, with the accuracy of traditional assessment methods still being questioned. This research proposed an objective assessment solution using inertial sensors, which showed promising results in distinguishing patients from healthy controls through the extraction of temporal and spectral features.
Article
Rheumatology
Daniel K. White, Jason Jakiela, Tom Bye, Jessica Aily, Dana Voinier
Summary: This scoping review aims to provide a basic overview of physical activity (PA), including terminology, the importance for adults with osteoarthritis (OA), and existing gaps in the literature. PA is defined as any energy expenditure from skeletal muscle above a resting level, and exercise is a planned, structured, and repetitive type of PA. Robust literature shows that PA has a modest protective effect on pain, functional limitation, and disability in OA, as well as positive effects on a range of outcomes in the general population. Recommendations for measurement instruments and metrics are provided.
JOURNAL OF RHEUMATOLOGY
(2023)
Article
Multidisciplinary Sciences
Tomasz Gutowski, Ryszard Antkiewicz, Stanislaw Szlufik
Summary: This paper presents a solution for creating personalized medicine intake schedules for Parkinson's disease patients. By using machine learning models and optimization algorithms, it can reduce treatment errors and the time required to establish medication schedules, with the potential to significantly improve treatment outcomes.
Article
Respiratory System
Narelle S. Cox, Beverley Eldridge, Sarah Rawlings, Julianna Dreger, Jennifer Corda, Jennifer Hauser, Brenda M. Button, Jennifer R. Bishop, Amanda Nichols, Anna Middleton, Nathan Ward, Tiffany Dwyer, Ruth Dentice, Raynuka Lazarus, Paul O'Halloran, Joanna Y. T. Lee, Christie Mellerick, Kelly Mackintosh, Melitta McNarry, Craig Anthony Williams, Anne E. Holland
Summary: The study found that a web-based application with individualized goal setting and real-time feedback was no more effective than usual care in promoting physical activity in young individuals with cystic fibrosis following hospital discharge. Both groups had high baseline physical activity levels, and engagement with the intervention was limited.
Article
Sport Sciences
Thomas A. Buckley, Barry A. Munkasy, Kelsey M. Evans, Brandy Clouse
Summary: This study found that mild to moderate physical activity and mental activity within the first 48 hours post-concussion were associated with reduced time to symptom recovery and return to participation, as opposed to lower or higher levels of activity.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Review
Rehabilitation
Renata Valle Pedroso, Adriano Eduardo Lima-Silva, Pietro Ernesto Tarachuque, Francisco Jose Fraga, Angelica Miki Stein
Summary: Physical exercise has significant effects on cortical activity in patients with MCI, both in acute and chronic responses. Various types of exercise alter EEG parameters, indicating neural plasticity in these individuals.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Clinical Neurology
Arnaldo Fim Neto, Julia Baldi de Luccas, Bruno Leonardo Bianqueti, Luiz Ricardo da Silva, Tiago Paggi Almeida, Andre Kazuo Takahata, Manoel Jacobsen Teixeira, Eberval Gadelha Figueiredo, Slawomir J. Nasuto, Maria Sheila Guimaraes Rocha, Diogo Coutinho Soriano, Fabio Godinho
Summary: This study investigated the dynamics of subthalamic nucleus local field potentials (STN-LFP) in Parkinson's disease patients and found differences in low-frequency beta bursts between tremor-dominant and postural instability and gait disorder phenotypes. These differences were correlated with motor symptoms.
CLINICAL NEUROPHYSIOLOGY
(2022)
Article
Respiratory System
Marc Spielmanns, Rainer Gloeckl, Inga Jarosch, Daniela Leitl, Tessa Schneeberger, Tobias Boeselt, Stephan Huber, Pawandeep Kaur-Bollinger, Bernhard Ulm, Claudia Mueller, Jonas Bjoerklund, Sabine Spielmanns, Wolfram Windisch, Anna-Maria Pekacka-Egli, Andreas Rembert Koczulla
Summary: This study investigated the effects of a smartphone application on maintaining physical activity in patients with COPD. The results showed that using the Kaia app can help patients maintain their physical activity levels after rehabilitation and improve related symptoms.
Review
Rehabilitation
Asher G. Kirk, Kate J. Behm, Lara A. Kimmel, Christina L. Ekegren
Summary: This systematic review synthesized evidence on physical activity and sedentary behavior during and after hospitalization, finding that patients tend to engage in more physical activity and less sedentary behavior at home compared to acute or subacute hospital settings. Enabling early discharge home through the implementation of home-hospitalization models may result in increased patient physical activity and reduced sedentary behavior, suggesting the potential benefits of such models on patient recovery and activity levels.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Rehabilitation
Stephen Leb, Christina Marciniak, Deborah Gaebler-Spira, Liqi Chen, Ariane Garrett
Summary: This study aimed to describe the relationship between activity level and cardiovascular risk measures, as well as the general activity patterns of adults with cerebral palsy. The study found that adults with GMFCS levels I or II who engaged in more activity tended to have more favorable anthropometric profiles, while those with GMFCS levels III, IV, or V did not show a similar trend.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Rehabilitation
Borja Perez-Dominguez, Jose Casana-Granell, Rafael Garcia-Maset, Alicia Garcia-Testal, Erika Melendez-Oliva, Eva Segura-Orti
Summary: This study compared nurse-led intradialytic exercise program with home-based exercise supervised by physical therapists in hemodialysis patients. Results showed significant improvements in functional capacity and health-related quality of life in both groups over 16 weeks.
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2021)
Article
Rehabilitation
Katie L. J. Cederberg, Brenda Jeng, Jeffer E. Sasaki, Robert W. Motl
Summary: This study examined the device-measured physical activity levels and sedentary behavior participation of adults with multiple sclerosis (MS) at different times of the day. The results showed that fatigued MS participants engaged in less moderate-to-vigorous physical activity, took fewer steps, and had more sedentary time compared to nonfatigued participants. Regardless of fatigue status, the highest levels of physical activity occurred in the morning and midday, while the highest levels of sedentary behavior were seen in the evening.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Clinical Neurology
Samuel Anfors, Ann-Sofi Kammerlind, Maria H. Nilsson
Summary: Single-item questions with a longer time frame (6 or 12 months) for physical activity were shown to be more reliable than multi-item questionnaires such as the IPAQ-SF and PASE in individuals with Parkinson's disease without cognitive impairments.
Article
Neuroimaging
Muthuraman Muthuraman, Marcell Palotai, Borbala Javor-Duray, Andrea Kelemen, Nabin Koirala, Laszlo Halasz, Lorand Eross, Gabor Fekete, Laszlo Bognar, Gunther Deuschl, Gertrud Tamas
Summary: Bradykinesia in Parkinson's disease is associated with beta and gamma band interactions in the basal ganglia-thalamocortical circuit. This study used EEG to identify neural networks predicting bradykinesia based on frequency-specific actions, revealing involvement of primary motor and premotor cortex as well as the subthalamic nucleus in movement dynamics.
NEUROIMAGE-CLINICAL
(2021)
Article
Neurosciences
Marcus de Lemos Fonseca, Jean-Francois Daneault, Gloria Vergara-Diaz, Ana Paula Quixada, Angelo Frederico Souza de Oliveira e Torres, Eduardo Ponde de Sena, Joao Paulo Bomfim Cruz Vieira, Bianca Bigogno Reis Cazeta, Vitor Sotero dos Santos, Thiago da Cruz Figueiredo, Norberto Pena, Paolo Bonato, Jose Garcia Vivas Miranda
EUROPEAN JOURNAL OF NEUROSCIENCE
(2020)
Letter
Rehabilitation
Aristide S. Honado, Jean-Sebastien Roy, Jean-Francois Daneault, Orthelo Leonel Gbetoho Atigossou, Charles Sebiyo Batcho
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE
(2020)
Article
Engineering, Biomedical
Brandon Oubre, Jean-Francois Daneault, Hee-Tae Jung, Kallie Whritenour, Jose Garcia Vivas Miranda, Joonwoo Park, Taekyeong Ryu, Yangsoo Kim, Sunghoon Ivan Lee
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2020)
Review
Pediatrics
Aurora James-Palmer, Ellen Z. Anderson, Lori Zucker, Yana Kofman, Jean-Francois Daneault
FRONTIERS IN PEDIATRICS
(2020)
Article
Chemistry, Multidisciplinary
Hee-Tae Jung, Jean-Francois Daneault, Tenzin Nanglo, Hyunsuk Lee, Byeongil Kim, Yangsoo Kim, Sunghoon Ivan Lee
APPLIED SCIENCES-BASEL
(2020)
Article
Neurosciences
Brandon Oubre, Jean-Francois Daneault, Kallie Whritenour, Nergis C. Khan, Christopher D. Stephen, Jeremy D. Schmahmann, Sunghoon Ivan Lee, Anoopum S. Gupta
Summary: This study analyzes sub-second movement profiles to extract characteristics of ataxia and trains machine learning models to objectively quantify ataxia severity. Movement decomposition reveals both expected and novel features of the ataxia phenotype, including distance, speed, duration, morphology, and temporal relationships of movements.
Article
Multidisciplinary Sciences
Gloria Vergara-Diaz, Jean-Francois Daneault, Federico Parisi, Chen Admati, Christina Alfonso, Matilde Bertoli, Edoardo Bonizzoni, Gabriela Ferreira Carvalho, Gianluca Costante, Eric Eduardo Fabara, Naama Fixler, Fatemah Noushin Golabchi, John Growdon, Stefano Sapienza, Phil Snyder, Shahar Shpigelman, Lewis Sudarsky, Margaret Daeschler, Lauren Bataille, Solveig K. Sieberts, Larsson Omberg, Steven Moore, Paolo Bonato
Summary: The study aimed to evaluate if wearable sensor data can be used to accurately estimate limb-specific symptom severity in Parkinson's disease patients. Nineteen PD patients performed motor tasks during laboratory visits and used a smartphone app for periodic tasks at home.
Article
Multidisciplinary Sciences
Jean-Francois Daneault, Gloria Vergara-Diaz, Federico Parisi, Chen Admati, Christina Alfonso, Matilde Bertoli, Edoardo Bonizzoni, Gabriela Ferreira Carvalho, Gianluca Costante, Eric Eduardo Fabara, Naama Fixler, Fatemah Noushin Golabchi, John Growdon, Stefano Sapienza, Phil Snyder, Shahar Shpigelman, Lewis Sudarsky, Margaret Daeschler, Lauren Bataille, Solveig K. Sieberts, Larsson Omberg, Steven Moore, Paolo Bonato
Summary: Parkinson's disease is a neurodegenerative disorder with motor and non-motor symptoms. Current treatments focus on managing motor symptoms, but treatment side-effects may emerge. The Levodopa Response Study aimed to objectively quantify symptom severity in PD patients using wearable sensor data.
Article
Engineering, Biomedical
Juhyeon Lee, Brandon Oubre, Jean-Francois Daneault, Christopher D. Stephen, Jeremy D. Schmahmann, Anoopum S. Gupta, Sunghoon Ivan Lee
Summary: This study proposes a new approach to estimate overall motor severity in cerebellar ataxia by analyzing the sub-second movement profiles of the lower-limbs during gait. The results show strong agreement between the estimated severity and clinician-evaluated scores, suggesting the accuracy of the proposed algorithm. This work is significant for monitoring disease progression and patients' responses to medical/clinical interventions.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2022)
Article
Rehabilitation
Aristide S. Honado, Orthelo Leonel Gbetoho Atigossou, Jean-Francois Daneault, Jean-Sebastien Roy, Charles Sebiyo Batcho
Summary: The study found a strong correlation between step counts and overall physical activity levels in able-bodied adults and stroke survivors in Benin. Step counts appear to be an indicator of physical activity levels in developing countries, suggesting walking as a potential exercise to improve physical activity levels in stroke survivors.
DISABILITY AND REHABILITATION
(2023)
Review
Health Care Sciences & Services
Aurora James-Palmer, Ellen Zambo Anderson, Jean-Francois Daneault
Summary: This scoping review analyzes the state of the literature on the remote delivery of yoga interventions. The review identifies several gaps, emphasizing the need for more attention to delivery methods and the importance of conducting studies with high methodological rigor and robust reporting.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Engineering, Biomedical
Yunda Liu, Brandon Oubre, Christian Duval, Sunghoon Ivan Lee, Jean-Francois Daneault
Summary: This study investigates the kinematic differences between HD chorea and PD LID and successfully develops a classification model to differentiate between them, laying the foundation for the development of a screening tool and providing insights into their pathophysiology.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2022)
Article
Public, Environmental & Occupational Health
Noha Algallai, Kelly Martin, Krupali Shah, Kusum Shrestha, Jean-Francois Daneault, Archana Shrestha, Abha Shrestha, Shristi Rawal
Summary: A study in Nepal evaluated the reliability and validity of the modified GPAQ questionnaire for assessing physical activity among pregnant women. The results showed that GPAQ is reliable for assessing moderate intensity physical activity but not sedentary behavior.
ARCHIVES OF PUBLIC HEALTH
(2023)
Article
Health Care Sciences & Services
Aurora M. James-Palmer, Jean-Francois Daneault
Summary: This study aimed to evaluate the safety and feasibility of a synchronous tele-yoga intervention for persons with Parkinson disease (PD). The results showed that the tele-yoga intervention was safe, feasible, usable, and enjoyable for persons with PD, with preliminary improvements observed in some clinically relevant outcome measures.
Article
Health Care Sciences & Services
Solveig K. Sieberts, Jennifer Schaff, Marlena Duda, Balint Armin Pataki, Ming Sun, Phil Snyder, Jean-Francois Daneault, Federico Parisi, Gianluca Costante, Udi Rubin, Peter Banda, Yooree Chae, Elias Chaibub Neto, E. Ray Dorsey, Zafer Aydin, Aipeng Chen, Laura L. Elo, Carlos Espino, Enrico Glaab, Ethan Goan, Fatemeh Noushin Golabchi, Yasin Gormez, Maria K. Jaakkola, Jitendra Jonnagaddala, Riku Klen, Dongmei Li, Christian McDaniel, Dimitri Perrin, Thanneer M. Perumal, Nastaran Mohammadian Rad, Erin Rainaldi, Stefano Sapienza, Patrick Schwab, Nikolai Shokhirev, Mikko S. Venalainen, Gloria Vergara-Diaz, Yuqian Zhang, Yuanjia Wang, Yuanfang Guan, Daniela Brunner, Paolo Bonato, Lara M. Mangravite, Larsson Omberg
Summary: Consumer wearables and sensors provide valuable data for disease monitoring, but converting these data into digital biomarkers requires complex analytical methods. This study used crowdsourcing to evaluate features derived from accelerometer and gyroscope data, successfully predicting the presence of Parkinson's disease and severity of three PD symptoms.
NPJ DIGITAL MEDICINE
(2021)
