4.0 Article

Microarray Image Based Cancer Prediction: An Genetic Invasive Weed Optimization Approach for Feature Selection

Journal

JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS
Volume 6, Issue 8, Pages 1934-1938

Publisher

AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jmihi.2016.1952

Keywords

Deoxy Ribonucleic Acid (DNA); Microarray; Feature Selection; Hybrid Genetic Invasive Weed Optimization (GIWO)

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Microarray imaging has enabled labeling of Ribonucleic Acid which in turn can be used for detecting diseases including cancer. It has been successfully used to predict Acute Lymphoblastic Leukemia (ALL), colon cancer, and Acute Myeloid Leukemia (AML). A challenge for classification algorithms is feature space's large size. Statistical techniques were used to reduce features but were sub-optimal as feature selection is NP-Hard. Various meta-heuristic techniques were proposed in literature to overcome NP-hard problem with varied success. Genetic Algorithm (GA) is useful for their global search capability but has poor convergence. This study proposes a new wrapper based feature selection technique using a hybrid Genetic Invasive Weed Optimization (GIWO). The new technique tested for AML and ALL classification showed promising results compared to statistical techniques.

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