Article
Clinical Neurology
Jurgen Germann, Brendan Santyr, Alexandre Boutet, Can Sarica, Clement T. Chow, Gavin J. B. Elias, Artur Vetkas, Andrew Yang, Mojgan Hodaie, Alfonso Fasano, Suneil K. Kalia, Michael L. Schwartz, Andres M. Lozano
Summary: Comparing the efficacy maps of DBS and MRgFUS suggests a potential alternative location for lesioning, more antero-superiorly. This may reduce complications, without sacrificing efficacy, and individualise targeting.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Chemistry, Multidisciplinary
Han-Song Wu, Shih-Min Wei, Shuo-Wen Chen, Han-Chi Pan, Wei-Pang Pan, Shih-Min Huang, Meng-Lin Tsai, Po-Kang Yang
Summary: This work reports the intrinsic piezoelectricity in metal-free perovskite films and evaluates their low toxicity. A piezoelectric nanogenerator is fabricated using the synthesized metal-free perovskite, demonstrating excellent output voltage and current. This work highlights the importance of perovskite-based generators for future advanced sensors and therapeutic systems.
Editorial Material
Biochemistry & Molecular Biology
Veerle Visser-Vandewalle, Pablo Andrade, Philip E. Mosley, Benjamin D. Greenberg, Rick Schuurman, Nicole C. McLaughlin, Valerie Voon, Paul Krack, Kelly D. Foote, Helen S. Mayberg, Martijn Figee, Brian H. Kopell, Mircea Polosan, Eileen M. Joyce, Stephan Chabardes, Keith Matthews, Juan C. Baldermann, Himanshu Tyagi, Paul E. Holtzheimer, Chris Bervoets, Clement Hamani, Carine Karachi, Damiaan Denys, Ludvic Zrinzo, Patric Blomstedt, Matilda Naesstrom, Aviva Abosch, Steven Rasmussen, Volker A. Coenen, Thomas E. Schlaepfer, Darin D. Dougherty, Philippe Domenech, Peter Silburn, James Giordano, Andres M. Lozano, Sameer A. Sheth, Terry Coyne, Jens Kuhn, Luc Mallet, Bart Nuttin, Marwan Hariz, Michael S. Okun
Summary: Deep brain stimulation is an effective but underutilized treatment for obsessive-compulsive disorder. Psychologists, psychiatrists, and insurers should take action to make this therapy accessible to patients with otherwise intractable cases, in order to improve their mental health.
Article
Engineering, Electrical & Electronic
Ziliang Zhou, Yicheng Yang, Jia Zeng, Xiaoxin Wang, Honghai Liu
Summary: This study focuses on exploring the parametric properties of electrotactile feedback using an electrical stimulation system and innovative measurement methods. The results show that the new bisection algorithm is more robust and achieves a 50% efficiency improvement, while individual differences and sensitivities can be quantified by the sensitivity index.
IEEE SENSORS JOURNAL
(2022)
Review
Rehabilitation
Ester Moreira de Castro-Carletti, Frauke Mueggenborg, Liz Dennett, Ana Izabela Sobral de Oliveira-Souza, Norazlin Mohamad, Adriana Pertille, Delaine Rodrigues-Bigaton, Susan Armijo-Olivo
Summary: This systematic review summarizes the evidence from randomized controlled trials and controlled trials on the effectiveness of electrotherapy in treating orofacial pain. The results show that transcutaneous electric nerve stimulation therapy can significantly reduce pain intensity and tenderness, demonstrating its effectiveness for patients with mixed temporomandibular disorders.
CLINICAL REHABILITATION
(2023)
Article
Chemistry, Analytical
Pawel Jurgielewicz, Tomasz Fiutowski, Ewa Kublik, Andrzej Skoczen, Malgorzata Szypulska, Piotr Wiacek, Pawel Hottowy, Bartosz Mindur
Summary: This paper introduces a modular Data Acquisition (DAQ) system for simultaneous electrical stimulation and recording of brain activity, with a focus on efficient software design and hardware performance. Results show that the Neurostim-3 system exhibits linear signal gain and is suitable for recording both Local Field Potential (LFP) and spiking brain activity signals. The hardware and software were proven to work efficiently and effectively in tandem, providing valuable insights into how the brain processes information.
Article
Engineering, Biomedical
Samuel Lienemann, Johan Zotterman, Simon Farnebo, Klas Tybrandt
Summary: This study developed a high performance soft and stretchable cuff electrode based on inert materials for low-voltage nerve stimulation. The stretchable cuff electrodes showed excellent stability under strain cycling and one million stimulation pulses, achieving saturated homogeneous stimulation of the sciatic nerve at only 200 mV. The combination of favourable mechanical properties and good electrode performance makes it ideal for low power supply applications within bioelectronic medicine.
JOURNAL OF NEURAL ENGINEERING
(2021)
Article
Biophysics
Jin Zhu, Baoguo Wang, Yixin Zhang, Tianxiang Wei, Tao Gao
Summary: Bioelectrical interfaces made of living electroactive bacteria (EAB) provide a unique opportunity to bridge biotic and abiotic systems, enabling the reprogramming of electrochemical biosensing. The engineering of EAB cells for biotarget recognition, sensing circuit construction, and electrical signal routing has demonstrated impressive capabilities in designing active sensing elements and developing electrically conductive interfaces on electrodes. Integration of engineered EAB into electrochemical biosensors can revolutionize bioelectronics research, with applications in environmental and health monitoring, green manufacturing, and other analytical fields.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Integrative & Complementary Medicine
Wen-jing Li, Chao Gao, Li-xin An, Yu-wei Ji, Fu-shan Xue, Yi Du
Summary: The study demonstrated that using TEAS in patients undergoing gastric and colorectal surgery can significantly shorten the time to first bowel motion, first flatus, and first ambulation, reduce the incidence of postoperative gastrointestinal dysfunction and postoperative nausea and vomiting.
JOURNAL OF INTEGRATIVE MEDICINE-JIM
(2021)
Review
Physiology
Thierry Paillard
Summary: Percutaneous electrical stimulation is a method used to improve functional capabilities in older individuals. The specific physiological needs of the individual determine whether neuromuscular electrical stimulation (NMES) or sensory electrical stimulation (SES) is most appropriate. NMES enhances muscle strength and motor output, while SES facilitates sensorimotor activity.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Multidisciplinary Sciences
Emanuel Gunnarsson, Kristian Rodby, Fernando Seoane
Summary: Electro-stimulation has been used successfully for years to alleviate spasticity, pain, and increase mobility. The Mollii-suit by Inerventions utilizes dry conductive rubber electrodes, eliminating the need for frequent replacement. However, fitting the garment on the body is cumbersome. This paper presents the possibility of using knitted dry electrodes instead, which have lower skin friction and can easily be fitted to the body. Through validating the performance of the garment using electrical parameters, it is concluded that knitting techniques can produce a seamlessly integrated garment with beneficial manufacturing and comfort perspectives.
SCIENTIFIC REPORTS
(2023)
Article
Biochemical Research Methods
Gal Shpun, Nairouz Farah, Yoav Chemla, Amos Markus, Tamar Azrad Leibovitch, Erel Lasnoy, Doron Gerber, Zeev Zalevsky, Yossi Mandel
Summary: This study optimized the fabrication process of a bio-functionalized 3D high-resolution retinal implant using SU-8 polymer and gold microelectrodes. The challenges in the fabrication process were overcome by utilizing a two-step bi-layer lift-off process and adding a bio-adhesion molecule. In-vitro and in-vivo experiments demonstrated the good structural design, long-term integration, and cell migration capability of the device in the rat sub-retinal space, and also showed the feasibility of subretinal neural stimulation using the fabricated device.
JOURNAL OF BIOLOGICAL ENGINEERING
(2023)
Editorial Material
Medicine, Research & Experimental
Michael S. Beauchamp, William H. Bosking, Denise Oswalt, Daniel Yoshor
Summary: The study successfully implanted an electrode array with 96 penetrating electrodes in the visual cortex of a blind patient, allowing the patient to perceive visual patterns created by passing current through array electrodes. Penetrating electrodes require less current to create a visual percept compared to electrodes resting on the cortical surface, but patterned electrical stimulation often fails to produce the expected percept, necessitating further research to understand the relationship between stimulus and perception.
JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Materials Science, Biomaterials
Jiajia Tang, Chengheng Wu, Zi Qiao, Jinkui Pi, Yusheng Zhang, Fang Luo, Jing Sun, Dan Wei, Hongsong Fan
Summary: In this study, a new concept of a light-powered oriented bioactive scaffold for remote and wireless electrical stimulation has been developed. By combining electrospinning and electrospraying techniques, a highly oriented polycaprolactone (PCL) microfibrous scaffold with co-sprayed bioactive collagen and photoelectric poly-3-hexylthiophene nanoparticles (P3HT NPs) was obtained. The results demonstrate that this scaffold can achieve specific photoelectric conversion effects, promoting the up-regulation of neuronal characteristic factors and the oriented elongation of cells.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Review
Chemistry, Multidisciplinary
Giorgio Conta, Alberto Libanori, Trinny Tat, Guorui Chen, Jun Chen
Summary: Current research focuses on developing self-powered IOB therapeutic devices using TENG technology, known for its bioconformability, low cost, simple manufacturability, and self-power capabilities. TENG-induced ES holds promise for novel therapeutic interventions and could pave the way for the development of personalized healthcare systems.
ADVANCED MATERIALS
(2021)
