Combining biomedical preventions for HIV: Vaccines with pre-exposure prophylaxis, microbicides or other HIV preventions

Review of efficacy trials of HIV-1/AIDS vaccines and regulatory lessons learned

(2016) Rebecca L. Sheets et al.   BIOLOGICALS

Scientific and regulatory challenges in evaluating clinical trial protocols for HIV-1/AIDS vaccines – A review from a regulatory perspective

(2016) Rebecca L. Sheets et al.   BIOLOGICALS

Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial

(2016) Sheena McCormack et al.   LANCET

Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women

(2016) Jared M. Baeten et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exploring the Potential Health Impact and Cost-Effectiveness of AIDS Vaccine within a Comprehensive HIV/AIDS Response in Low- and Middle-Income Countries

(2016) Thomas M. Harmon et al.   PLoS One

Selection of HIV vaccine candidates for concurrent testing in an efficacy trial

(2016) Ying Huang et al.   Current Opinion in Virology

Which New Health Technologies Do We Need to Achieve an End to HIV/AIDS?

(2016) Glenda E. Gray et al.   PLOS BIOLOGY

Prospects for a Globally Effective HIV-1 Vaccine

(2015) Jean-Louis Excler et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

(2015) Jeanne M. Marrazzo et al.   NEW ENGLAND JOURNAL OF MEDICINE

On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection

(2015) Jean-Michel Molina et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Polyvalent Clade B Virus-Like Particle HIV Vaccine Combined with Partially Protective Oral Preexposure Prophylaxis Prevents Simian–Human Immunodeficiency Virus Infection in Macaques and Primes for Virus-Amplified Immunity

(2014) Ted M. Ross et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Accelerating HIV-1 Vaccine Efficacy Trials

(2014) Dan H. Barouch et al.   CELL

In Pursuit of an HIV Vaccine: Designing Efficacy Trials in the Context of Partially Effective Nonvaccine Prevention Modalities

(2013) Holly Janes et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial

(2013) Kachit Choopanya et al.   LANCET

Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine

(2013) Scott M. Hammer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Heterosexual Anal Intercourse: A Neglected Risk Factor for HIV?

(2012) Rebecca F. Baggaley et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Antibodies with High Avidity to the gp120 Envelope Protein in Protection from Simian Immunodeficiency Virus SIVmac251Acquisition in an Immunization Regimen That Mimics the RV-144 Thai Trial

(2012) Poonam Pegu et al.   JOURNAL OF VIROLOGY

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

(2012) Barton F. Haynes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiretroviral Preexposure Prophylaxis for Heterosexual HIV Transmission in Botswana

(2012) Michael C. Thigpen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women

(2012) Jared M. Baeten et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preexposure Prophylaxis for HIV Infection among African Women

(2012) Lut Van Damme et al.   NEW ENGLAND JOURNAL OF MEDICINE

Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission

(2012) D. H. Barouch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delay of simian human immunodeficiency virus infection and control of viral replication in vaccinated macaques challenged in the presence of a topical microbicide

(2011) Cecilia Cheng-Mayer et al.   AIDS

Tenofovir Selectively Regulates Production of Inflammatory Cytokines and Shifts the IL-12/IL-10 Balance in Human Primary Cells

(2011) Jesper Melchjorsen et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Statistical Interpretation of the RV144 HIV Vaccine Efficacy Trial in Thailand: A Case Study for Statistical Issues in Efficacy Trials

(2011) P. B. Gilbert et al.   JOURNAL OF INFECTIOUS DISEASES

Natural Substrate Concentrations Can Modulate the Prophylactic Efficacy of Nucleotide HIV Reverse Transcriptase Inhibitors

(2011) J. G. Garcia-Lerma et al.   JOURNAL OF VIROLOGY

Safety and efficacy of the HVTN 503/Phambili Study of a clade-B-based HIV-1 vaccine in South Africa: a double-blind, randomised, placebo-controlled test-of-concept phase 2b study

(2011) Glenda E Gray et al.   LANCET INFECTIOUS DISEASES

AIDS Vaccines and Preexposure Prophylaxis: Is Synergy Possible?

(2010) Jean-Louis Excler et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

(2010) Robert M. Grant et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women

(2010) Q. Abdool Karim et al.   SCIENCE

Intermittent Prophylaxis with Oral Truvada Protects Macaques from Rectal SHIV Infection

(2010) J. G. Garcia-Lerma et al.   Science Translational Medicine

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET