High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis

Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

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Perspective: The RNA exosome, cytokine gene regulation and links to autoimmunity

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Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation

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(2015) C. J. Marsit   JOURNAL OF EXPERIMENTAL BIOLOGY

The influence of polygenic risk scores on heritability of anti-CCP level in RA

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Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis

(2014) Anca I. Catrina et al.   Nature Reviews Rheumatology

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins

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Multiplex Analyses of Antibodies Against Citrullinated Peptides in Individuals Prior to Development of Rheumatoid Arthritis

(2013) Mikael Brink et al.   ARTHRITIS AND RHEUMATISM

Familial Risks and Heritability of Rheumatoid Arthritis: Role of Rheumatoid Factor/Anti-Citrullinated Protein Antibody Status, Number and Type of Affected Relatives, Sex, and Age

(2013) Thomas Frisell et al.   ARTHRITIS AND RHEUMATISM

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Charting a dynamic DNA methylation landscape of the human genome

(2013) Michael J. Ziller et al.   NATURE

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

(2013) Yun Liu et al.   NATURE BIOTECHNOLOGY

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

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DNA methylation arrays as surrogate measures of cell mixture distribution

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Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases

(2012) Peter M. Clark et al.   INFLAMMATORY BOWEL DISEASES

Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies

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Protocadherins mediate dendritic self-avoidance in the mammalian nervous system

(2012) Julie L. Lefebvre et al.   NATURE

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

Analysing and interpreting DNA methylation data

(2012) Christoph Bock   NATURE REVIEWS GENETICS

Protocadherin-18 Is a Novel Differentiation Marker and an Inhibitory Signaling Receptor for CD8+ Effector Memory T Cells

(2012) Edwin J. Vazquez-Cintron et al.   PLoS One

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

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The Swedish Twin Registry: Establishment of a Biobank and Other Recent Developments

(2012) Patrik K. E. Magnusson et al.   Twin Research and Human Genetics

The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates

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Epigenome-wide association studies for common human diseases

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The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia

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Accurate genome-scale percentage DNA methylation estimates from microarray data

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Clustered protocadherin family

(2010) Takeshi Yagi   DEVELOPMENT GROWTH & DIFFERENTIATION

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

Predicting arthritis outcomes--what can be learned from the Leiden Early Arthritis Clinic?

(2010) D. P. C. de Rooy et al.   RHEUMATOLOGY

Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis

(2009) E W Karlson et al.   ANNALS OF THE RHEUMATIC DISEASES

DNA hypomethylation in rheumatoid arthritis synovial fibroblasts

(2009) Emmanuel Karouzakis et al.   ARTHRITIS AND RHEUMATISM

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(2009) Lars Klareskog et al.   LANCET

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

Epigenetics in human autoimmunity

(2008) Faith M. Strickland et al.   AUTOIMMUNITY

Comprehensive high-throughput arrays for relative methylation (CHARM)

(2008) R. A. Irizarry et al.   GENOME RESEARCH