CRISPR-Mediated Drug-Target Validation Reveals Selective Pharmacological Inhibition of the RNA Helicase, eIF4A

Title
CRISPR-Mediated Drug-Target Validation Reveals Selective Pharmacological Inhibition of the RNA Helicase, eIF4A
Authors
Keywords
rocaglates, eIF4A, translational control, chemical biology, CRISPR/Cas9
Journal
Cell Reports
Volume 15, Issue 11, Pages 2340-2347
Publisher
Elsevier BV
Online
2016-05-27
DOI
10.1016/j.celrep.2016.05.005

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