Interleukin 34: a new modulator of human and experimental inflammatory bowel disease

Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection

(2015) Hitokazu Esaki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Th17 and Non-Classic Th1 Cells in Chronic Inflammatory Disorders: Two Sides of the Same Coin

(2014) Lorenzo Cosmi et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Immunopathology of inflammatory bowel disease

(2014) Kori L Wallace   WORLD JOURNAL OF GASTROENTEROLOGY

Combination Therapy With Infliximab and Azathioprine Is Superior to Monotherapy With Either Agent in Ulcerative Colitis

(2013) Remo Panaccione et al.   GASTROENTEROLOGY

Functional bowel symptoms in quiescent inflammatory bowel diseases: role of epithelial barrier disruption and low-grade inflammation

(2013) M Vivinus-Nébot et al.   GUT

Elevated Serum and Synovial Fluid Levels of Interleukin-34 in Rheumatoid Arthritis: Possible Association with Disease Progression via Interleukin-17 Production

(2013) Ye Tian et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Origin of monocytes and macrophages in a committed progenitor

(2013) Jan Hettinger et al.   NATURE IMMUNOLOGY

CSF-1 Receptor-Dependent Colon Development, Homeostasis and Inflammatory Stress Response

(2013) Duy Huynh et al.   PLoS One

The Newly Discovered Cytokine IL-34 Is Expressed in Gingival Fibroblasts, Shows Enhanced Expression by Pro-Inflammatory Cytokines, and Stimulates Osteoclast Differentiation

(2013) Elisabeth A. Boström et al.   PLoS One

IL-34 is overexpressed in the inflamed salivary glands of patients with Sjogren's syndrome and is associated with the local expansion of pro-inflammatory CD14brightCD16+ monocytes

(2013) F. Ciccia et al.   RHEUMATOLOGY

Mechanisms of tumor necrosis factor-alpha-induced leaks in intestine epithelial barrier

(2012) Fang He et al.   CYTOKINE

The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation

(2012) Sayan Nandi et al.   DEVELOPMENTAL BIOLOGY

Differences in the location and activity of intestinal Crohn’s disease lesions between adult and paediatric patients detected with MRI

(2012) Francesca Maccioni et al.   EUROPEAN RADIOLOGY

Ulcerative colitis

(2012) Ingrid Ordás et al.   LANCET

Crohn's disease

(2012) Daniel C Baumgart et al.   LANCET

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

(2012) C C Bain et al.   Mucosal Immunology

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

(2012) Yaming Wang et al.   NATURE IMMUNOLOGY

Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R

(2012) Xiaolei Ma et al.   STRUCTURE

Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients

(2011) M Chemel et al.   ANNALS OF THE RHEUMATIC DISEASES

Regulation of Homeostasis and Inflammation in the Intestine

(2011) Thomas T. MacDonald et al.   GASTROENTEROLOGY

Functional Specializations of Intestinal Dendritic Cell and Macrophage Subsets That Control Th17 and Regulatory T Cell Responses Are Dependent on the T Cell/APC Ratio, Source of Mouse Strain, and Regional Localization

(2011) T. L. Denning et al.   JOURNAL OF IMMUNOLOGY

Intestinal growth factors: Potential use in the treatment of inflammatory bowel disease and their role in mucosal healing

(2010) Kumar Krishnan et al.   INFLAMMATORY BOWEL DISEASES

Oral TNF-α gene silencing using a polymeric microsphere-based delivery system for the treatment of inflammatory bowel disease

(2010) Christina Kriegel et al.   JOURNAL OF CONTROLLED RELEASE

Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

(2010) Suwen Wei et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Clinical trial: benefits and risks of immunomodulators and maintenance infliximab for IBD-subgroup analyses across four randomized trials

(2009) G. R. LICHTENSTEIN et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Infliximab in Crohn's disease: early and long-term treatment

(2008) A. Armuzzi et al.   DIGESTIVE AND LIVER DISEASE

Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial

(2008) Geert D'Haens et al.   LANCET

Discovery of a Cytokine and Its Receptor by Functional Screening of the Extracellular Proteome

(2008) H. Lin et al.   SCIENCE