Article
Entomology
Gianluca Paventi, Giuseppe Rotundo, Marco Pistillo, Ilaria D'Isita, Giacinto Salvatore Germinara
Summary: Hop crude extracts (methanol, acetone, and n-hexane) showed contact toxicity and repellent activity against Sitophilus granarius, along with anticholinesterase activity. These findings suggest the potential use of hop as an effective botanical insecticide against S. granarius.
Article
Agriculture, Multidisciplinary
Mariana B. C. Pinto, Flavio L. Schmidt, Juri Rappsilber, Brian Gibson, Philip C. Wietstock
Summary: This study aimed to clarify the role of hop bitter acids in protein aggregate formation in beer using a proteomic approach. The results showed that hop bitter acids primarily bound to low abundant proteins, unrelated to beer quality traits such as foam or haziness, and caused the precipitation of specific proteins during boiling.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Obstetrics & Gynecology
Ho-Geun Kang, Hee-Yun Kim, Hyunwoo Jee, Hwanseok Jun, Hosong Cho, Dongjun Park, Hyun-Jong Ahn, Hyung-Min Kim, Hyun-Ja Jeong
Summary: The compound of Cynanchum wilfordii and Humulus lupulus L. (CWHL) has been found to effectively relieve menopausal symptoms in ovariectomized mice by regulating biomarkers associated with depression, hot flashes, and osteoporosis.
REPRODUCTIVE SCIENCES
(2023)
Article
Food Science & Technology
Byungjick Min, Yejin Ahn, Hyeok-Jun Cho, Woong-Kwon Kwak, Kyungae Jo, Hyung Joo Suh
Summary: This study investigated the sleep-promoting effects of different hop extracts in invertebrate and vertebrate models. Citra had a high alpha-acid content, while Saphir had high beta-acid and xanthohumol content. Simcoe and Mosaic water extracts and Saphir and Simcoe ethanol extracts increased total nighttime sleep in Drosophila melanogaster. They also improved total sleep time in mice with pentobarbital-induced sleep and upregulated the mRNA expression of GABA receptors in mouse brains.
JOURNAL OF FOOD SCIENCE
(2023)
Article
Plant Sciences
Nicolo Iacuzzi, Francesco Salamone, Davide Farruggia, Noemi Tortorici, Lorena Vultaggio, Teresa Tuttolomondo
Summary: In this study, in vitro propagation technique was applied to the Cascade variety of Humulus lupulus L. The results showed that the highest shoot percentage was obtained with a culture medium containing the highest TDZ doses in combination with cytokinin. The highest rooting percentage, roots numbers and root length were found when the culture medium was supplemented with IAA. The use of agri-perlite and half concentration of MS basal medium without PGR allowed for a 99.1% survival rate.
Article
Food Science & Technology
Mariana Barreto Carvalhal Pinto, Renata Vardanega, Grazielle Nathia-Neves, Pedro Renann Lopes de Franca, Louise Emy Kurozawa, Maria Angela A. Meireles, Flavio Luis Schmidt
Summary: Hop cultivation has been on the rise in Brazil over the past decade, necessitating a greater understanding of how processing affects domestic hop varieties. This study focused on evaluating the impact of drying and supercritical CO2 extraction on hop extract quality. The research optimized the hop processing to improve extract quality while saving energy and reducing the process footprint. Additionally, the study established supercritical CO2 extraction conditions for Brazilian hop extract production, offering a cost-effective alternative for the national beer industry.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Lorenzo Lamberti, Giorgio Grillo, Lorenzo Gallina, Diego Carnaroglio, Farid Chemat, Giancarlo Cravotto
Summary: This study aimed to design an optimized extraction protocol using microwaves for the volatile fraction (VF) from hops, and investigate the impact of different hop forms on the extraction efficiency. The results showed that extraction in a pilot reactor could achieve higher yields and save more energy.
Article
Chemistry, Multidisciplinary
Martina Grdisa, Zlatko Satovic, Zlatko Liber, Jernej Jakse, Filip Varga, Renata Erhatic, Sinisa Srecec
Summary: The study used microsatellite markers to analyze the genetic diversity and differentiation of wild hop populations in northwestern Croatia, revealing high diversity, weak population differentiation, and substantial gene flow among populations.
APPLIED SCIENCES-BASEL
(2021)
Article
Plant Sciences
Ajay Kumar Mishra, Tomas Kocabek, Vishnu Sukumari Nath, Ahamed Khan, Jaroslav Matousek, Khaled M. Hazzouri, Naganeeswaran Sudalaimuthuasari, Karel Krofta, Jutta Ludwig-Mueller, Khaled M. A. Amiri
Summary: This study investigates the regulatory functions of the HlMYB7 transcription factor in the biosynthesis pathway and accumulation of prenyl-flavonoids (PF) and bitter acids (BA) in hop. HlMYB7 represses the transcription of structural genes involved in the terminal steps of PF and BA biosynthesis, resulting in stunted growth, delayed flowering, and reduced tolerance to viroid infection in hop.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Plant Sciences
Josef Patzak, Alena Henychova, Karel Krofta, Petr Svoboda, Ivana Malirova
Summary: Viroids are small infectious pathogens composed of short single-stranded circular RNA. The study evaluated the impact of HLVd infection on secondary metabolite content and composition in mature hop cones, as well as gene expression analyses in different hop cultivars. Viroid infection significantly reduced the contents of alpha bitter acids and xanthohumol, and affected gene expression related to secondary metabolite biosynthesis.
Review
Horticulture
Jessiane Mary Jastrombek, Mariana Mendes Faguerazzi, Hyan de Cassio Pierezan, Leo Rufato, Alessandro Jefferson Sato, Wilian da Silva Ricce, Viviani Vieira Marques, Nathalia Rodrigues Leles, Sergio Ruffo Roberto
Summary: Brazil is one of the top three beer producers globally and has witnessed the emergence of hop cultivation in recent years due to the rise in craft breweries. The main challenge lies in adapting hop cultivars to the photoperiod conditions in subtropical regions. This review provides a historical overview of hop cultivation in Brazil and characterizes the climatic elements of emerging subtropical regions to support the development of new technologies for hop cultivation.
Article
Plant Sciences
Nathalia Rodrigues Leles, Alessandro Jefferson Sato, Leo Rufato, Jessiane Mary Jastrombek, Viviani Vieira Marques, Robson Fernando Missio, Nelson Luis Mello Fernandes, Sergio Ruffo Roberto
Summary: The objective of this study was to determine the duration of phenological stages, growth development, yield, and cone quality of hop cultivars under artificial light in a subtropical climate. The study was conducted in Brazil during 2021 and 2022. Different cultivars were used in the experiment, and various measurements were recorded, including plant height, fresh mass, number of lateral branches, cone characteristics, and chemical components. The results showed that the early-maturing cultivars had higher yields and better cone quality. Yakima Gold cultivar exhibited positive correlations with chemical components of the cones.
Article
Microbiology
Patricia Fonseca Duarte, Lucas Henrique do Nascimento, Bruno Fischer, Andreia Menin Lohmann, Valmor Jose Bandiera, Ilizandra Aparecida Fernandes, Jacir Dal Magro, Eunice Valduga, Rogerio Luis Cansian, Natalia Paroul, Alexander Junges
Summary: This study evaluated the chemical composition, essential oil (EO) yield, and antibacterial activity of hop essential oil from Chinook hops at different extraction times. The major compounds of hop EO were alpha-humulene, beta-myrcene, and beta-caryophyllene. The EO extracted in 300 minutes showed the most efficient antibacterial activity against L. brevis.
CURRENT MICROBIOLOGY
(2023)
Article
Chemistry, Analytical
Emanuela Salviati, Eduardo Sommella, Albino Carrizzo, Veronica Di Sarno, Alessia Bertamino, Eleonora Venturini, Carmine Vecchione, Pietro Campiglia
Summary: This study aimed to elucidate the metabolic stability of bitter acids in hops using a novel method, leading to the discovery of 33 compounds including various oxidized metabolites and glucuronide conjugates.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
Article
Plant Sciences
Valentina Macchioni, Valentina Picchi, Katya Carbone
Summary: This study investigates the effects of two different drying methods on the nutraceutical profile, pigment content, and antioxidant potential of leaves from five different Humulus lupulus varieties. The results show that freeze-drying is the most suitable drying method for the overall phytochemical profile, while oven drying provides higher carotenoid retention depending on the genotype considered.
Review
Dermatology
Mina Amiri, Aida Fallahzadeh, Ali Sheidaei, Fatemeh Mahboobifard, Fahimeh Ramezani Tehrani
Summary: The meta-analysis revealed a pooled prevalence of 7.74% for IH in women, with no significant differences found based on PCOS criteria and ethnicity subgroups.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Psychiatry
Mehrnoosh Hosseinpoor, Seyedeh Zahra Masoumi, Farideh Kazemi, Farzaneh Soltani, Mohammad Ahmadpanah
Summary: This study aims to determine the effect of couple-centered counseling by the Gottman method on marital intimacy of infertile couples. The results show that counseling based on the Gottman method can increase marital intimacy and improve the relationship issues of infertile couples during the treatment process.
Review
Nutrition & Dietetics
Nazanin Moslehi, Sheida Zeraattalab-Motlagh, Fatemeh Rahimi Sakak, Sakineh Shab-Bidar, Fahimeh Ramezani Tehrani, Parvin Mirmiran
Summary: There is no high-certainty evidence that diets alone improve health or reproductive outcomes in women with PCOS. However, supplementation with vitamin D, probiotics/synbiotics, omega-3, inositol, and curcumin has favorable effects on some metabolic outcomes.
Review
Dermatology
Mina Amiri, Leila Mahmoudieh, Ali Sheidaei, Fahimeh Ramezani Tehrani
Summary: This study aimed to evaluate the lipid profiles in women with idiopathic hirsutism (IH) compared to those of polycystic ovary syndrome (PCOS) and healthy controls. The meta-analysis results showed that the levels of total cholesterol were slightly higher and high-density lipoprotein cholesterol were slightly lower in women with IH compared to healthy controls. There were no significant differences in the levels of triglyceride and low-density lipoprotein cholesterol between the study groups. The levels of lipid profiles were also not significantly different between women with IH and PCOS patients, except for triglyceride levels.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Review
Endocrinology & Metabolism
S. Nazarpour, F. Ramezani Tehrani, R. Valizadeh, M. Amiri
Summary: This systematic review and meta-analysis found that exposure to air pollutants, especially PM2.5, PM10, O3, and SO2, increases the risk of gestational diabetes mellitus (GDM).
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Article
Multidisciplinary Sciences
Sara Armandpishe, Reza Pakzad, Mohammadamin Jandaghian-Bidgoli, Fatemeh Abdi, Maryam Sardashti, Kimia Soltaniha
Summary: The aim of this study was to investigate the main factors affecting the prevalence of stress, anxiety, and depression among citizens of Karaj. The results showed that gender and economic status were the most influential factors in the incidence of these problems.
Article
Public, Environmental & Occupational Health
Maryam Farahmand, Parisa Amiri, Fahimeh Ramezani Tehrani, Leila Cheraghi, Fereidoun Azizi
Summary: This study explores the relationship between spiritual health and health-related quality of life in different stages of life in healthy women. The study found that higher spiritual health is associated with higher mental health and overall quality of life. These findings can be used to develop programs aimed at improving psychological health in women.
Article
Endocrinology & Metabolism
Mahbanoo Farhadi-Azar, Marzieh Saei Ghare Naz, Mehrdad Ghahremani, Maryam Mousavi, Fereidoun Azizi, Fahimeh Ramezani Tehrani
Summary: This study aimed to examine the prevalence of self-reported male infertility and related metabolic disturbances. It was found that the total prevalence of self-reported male infertility was 6.42%. Male infertility was positively associated with total cholesterol and hip circumference, indicating the importance of addressing these risk factors.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM
(2023)
Article
Public, Environmental & Occupational Health
Farzaneh Ashrafinia, Hui Chen, Omolbanin Heydari, Maryam Mirzaei, Fatemeh Abdi
Summary: The COVID-19 pandemic has had significant effects on pregnant and breastfeeding women. Preventive behaviors and postpartum distress levels changed significantly during the study. Breastfeeding practices were negatively affected by postpartum distress, unwanted pregnancies, and cesarean delivery.
MATERNAL AND CHILD HEALTH JOURNAL
(2023)
Article
Obstetrics & Gynecology
Mahsa Noroozzadeh, Maryam Rahmati, Mahbanoo Farhadi-Azar, Marzieh Saei Ghare Naz, Fereidoun Azizi, Fahimeh Ramezani Tehrani
Summary: The study aimed to determine the impact of maternal hyperandrogenism (MHA) on the risk of metabolic syndrome (MetS) in female offspring in their later life. The results showed that female offspring with MHA had a higher risk of developing MetS compared to controls. Therefore, screening for MetS in these female offspring may be recommended.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Review
Medicine, General & Internal
Zahra Atarodi Kashani, Reza Pakzad, Farzaneh Rashidi Fakari, Mohammad Sadegh Haghparast, Fatemeh Abdi, Zohreh Kiani, Afsaneh Talebi, Somaieh Moradi Haghgoo
Summary: This study investigated the effect of electromagnetic waves on fetal and childhood abnormalities. The results showed that parents exposed to electromagnetic waves had a higher incidence of abnormal events in their fetuses and children, including changes in gene expression, oxidant parameters, antioxidant parameters, and DNA damage parameters. Additionally, parental exposure to radiation could lead to different types of cancers and developmental disorders. The publication year had a significant effect on heterogeneity according to meta-regression analysis.
Article
Obstetrics & Gynecology
Maryam Asltoghiri, Lida Moghaddam-Banaem, Samira Behboudi-Gandevani, Abbas Rahimi Froushani, Fahimeh Ramezani Tehrani
Summary: This study aimed to identify the optimal cutoff values of each component of metabolic syndrome (MetS) in the first trimester of pregnancy for predicting adverse pregnancy outcomes. Receiver operating characteristic (ROC) curve analysis using the Youden's index was used to obtain the cutoff values for each MetS component.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Sima Nazarpour, Fahimeh Ramezani Tehrani, Firoozeh Sajedi, Maryam Rahmati, Razieh Bidhendi Yarandi, Fereidoun Azizi
Summary: This study aimed to evaluate the effects of levothyroxine therapy on the neurodevelopment of infants born to pregnant women with subclinical hypothyroidism. The results showed that levothyroxine therapy had no significant beneficial effect on the neurodevelopment of children in the first three years of life.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2023)
Review
Health Care Sciences & Services
Teamur Aghamolaei, Asiyeh Pormehr-Yabandeh, Zahra Hosseini, Nasibeh Roozbeh, Mandieh Arian, Amin Ghanbarnezhad
Summary: The meta-analysis shows that pregnancy in women with sickle cell disease is associated with increased risks of adverse outcomes for the mothers, fetus, and patients with different genotypes. Therefore, careful multidisciplinary management and cautious care are needed to decrease maternal and fetal morbidity and mortality in sickle cell hemoglobinopathies pregnancies.
ETHIOPIAN JOURNAL OF HEALTH SCIENCES
(2022)
Review
Medicine, General & Internal
Fatemeh Alsadat Rahnemaei, Fatemeh Abdi, Elham Kazemian, Negar Shaterian, Negin Shaterian, Fatemeh Behesht Aeen
Summary: Gestational diabetes mellitus is a common and rising complication in pregnancy. This systematic review found an association between body mass index in the first half of pregnancy and gestational diabetes mellitus. Pregnant women with higher body mass index in the first half of pregnancy are at a higher risk for gestational diabetes mellitus.
SAGE OPEN MEDICINE
(2022)