Article
Anesthesiology
Marc-Olivier Fischer, Pierre-Gregoire Guinot, Stephane Debroczi, Pierre Huette, Christophe Beyls, Gerard Babatasi, Kevin Bafi, Mathieu Guilbart, Thierry Caus, Emmanuel Lorne, Herve Dupont, Jean-Luc Hanouz, Momar Diouf, Osama Abou-Arab
Summary: An individualized strategy based on a central venous oxygen saturation threshold of 70% allows for a more restrictive red blood cell transfusion strategy with no increase in postoperative morbidity or 6-month mortality.
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Article
Critical Care Medicine
Seyed Hamid Salehi, Maziar Daniali, Paniz Motaghi, Mahnoush Momeni
Summary: A study on adjusting transfusion thresholds for burn patients found that a more restrictive transfusion strategy significantly reduces the number of transfusions without increasing complications or mortality rates, while also saving costs and reducing infection rates.
Article
Ecology
Zhe Chen, Omer Nevo, Kim Valenta, Hang Sun, Yang Niu
Summary: Red fruits have lower color diversity than red flowers, with redder hues and fewer secondary reflectance peaks. Avian color vision models illustrated that fruits were more conspicuous than flowers achromatically, but not chromatically. Pigeons did not show preference for red with or without a secondary peak.
FUNCTIONAL ECOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Charlotta Pisinger, Cecilie Goltermann Toxvaerd, Mette Rasmussen
Summary: The study aimed to compare the impact of financial incentives and campaign advertisements on recruitment and smoking cessation rates among smokers. The results showed no significant difference between the two methods in terms of self-reported continuous abstinence, but financial incentives were found to be more effective in achieving validated abstinence at one-year follow-up.
PREVENTIVE MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Yeshen Zhang, Zhengrong Xu, Yuming Huang, Qirao Ye, Nianjin Xie, Lihuan Zeng, Xingji Lian, Yining Dai, Jiyan Chen, Pengcheng He, Ning Tan, Yuanhui Liu
Summary: Both restrictive and liberal red blood cell transfusion strategies have similar effects on overall mortality and follow-up mortality in anemic AMI patients, but restrictive transfusion tends to have a higher risk of in-hospital mortality. There were no significant differences between the two groups in secondary outcomes, suggesting that further evaluation of transfusion strategy is needed in future studies.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Computer Science, Artificial Intelligence
Shaojing Fan, Zhiqi Shen, Bryan L. Koenig, Tian-Tsong Ng, Mohan S. Kankanhalli
Summary: Research shows that the preference for videos over images in research and applications may not always be correct when it comes to evoking emotions in human observers. Static frames and videos elicit most emotions similarly, but static frames elicit negative emotions more strongly. These interdisciplinary findings have important implications for various fields, including social psychology, computer vision, mass media, and marketing.
IEEE TRANSACTIONS ON AFFECTIVE COMPUTING
(2023)
Article
Medicine, General & Internal
Christoph Jaenig, Chadlia Willms, Jens Schwietring, Christoph Guesgen, Arnulf Willms, Nicole Didion, Tobias Gruebl, Dan Bieler, Willi Schmidbauer
Summary: This study analyzed data from 37 German air rescue stations between 2015 and 2020 to assess the incidence of massive hemorrhage after trauma and the potential need for prehospital blood transfusions. The study found that although the incidence of hemorrhagic trauma patients is low, the prehospital administration of blood products may serve as a life-saving bridging treatment.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Hyeon-Ki Kim, Shota Furuhashi, Masaki Takahashi, Hanako Chijiki, Takuya Nanba, Takayuki Inami, Zsolt Radak, Shizuo Sakamoto, Shigenobu Shibata
Summary: Late afternoon endurance exercise is more effective than morning endurance exercise at improving 24-hour glucose and triglyceride levels.
FRONTIERS IN ENDOCRINOLOGY
(2022)
News Item
Medicine, General & Internal
Rita Rubin
Summary: This Quick Uptake examines the relationship between statin use and mortality risk in people with COVID-19.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Review
Neurosciences
Araceli Diaz-Ruiz, Juan Nader-Kawachi, Francisco Calderon-Estrella, Alfonso Mata-Bermudez, Laura Alvarez-Mejia, Camilo Rios
Summary: Dapsone is a safe and effective treatment drug with neuroprotective and cytoprotective effects. Research has shown that it can regulate and reduce the main mechanisms of damage that lead to cell death.
CURRENT NEUROPHARMACOLOGY
(2022)
Article
Pediatrics
Yvonne A. Eiby, Ian M. R. Wright, Michael J. Stark, Barbara E. Lingwood
Summary: The study aimed to determine the effectiveness of volume expansion with saline or packed red blood cells (RBC) in supporting cardiovascular function in preterm piglets. It was found that RBC infusion significantly increased blood volume and improved measures of cardiovascular function, cerebral oxygenation, and metabolic acidosis. In contrast, saline infusion did not increase blood volume or improve cardiovascular function, cerebral oxygenation, or metabolic acidosis.
PEDIATRIC RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Andreas Nord, Neil B. Metcalfe, Jennifer L. Page, Anna Huxtable, Dominic J. McCafferty, Neal J. Dawson
Summary: This study examined the changes in mitochondrial function in endotherms in cold regions preparing for winter, with findings showing that Coal and Great tits increased their mitochondrial respiration rate and volume in winter to enhance heat production capacity.
Article
Psychology, Multidisciplinary
Qiudong Xia, Lu'an Ke, Zheng Zheng
Summary: This study investigates the effectiveness of creating and sharing videos with classmates compared to merely creating videos and self-exercise in terms of intrinsic motivation, perseverance in learning, learning satisfaction, and roller-skating skill. The findings suggest that creating and sharing videos with classmates increases students' intrinsic motivation, perseverance in motor tasks, and learning satisfaction, but does not significantly improve roller-skating skill.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Multidisciplinary Sciences
Baojing Gu, Lin Zhang, Rita Van Dingenen, Massimo Vieno, Hans J. M. Van Grinsven, Xiuming Zhang, Shaohui Zhang, Youfan Chen, Sitong Wang, Chenchen Ren, Shilpa Rao, Mike Holland, Wilfried Winiwarter, Deli Chen, Jianming Xu, Mark A. Sutton
Summary: The study shows that nitrogen contributes significantly to global PM2.5 exposure and has a substantial impact on global health. Controlling ammonia emissions has a lower cost compared to nitrogen oxides emissions, emphasizing the priority for reducing ammonia emissions.
Article
Engineering, Biomedical
Sander De Bock, Jo Ghillebert, Renee Govaerts, Shirley A. Elprama, Uros Marusic, Ben Serrien, An Jacobs, Joost Geeroms, Romain Meeusen, Kevin De Pauw
Summary: The study evaluated the effectiveness of two passive shoulder exoskeletons in both laboratory and field settings. Results showed that the exoskeletons reduced upper trapezius activity and heart rate in isolated tasks, but their effects were limited in real-world situations. Improvement in exoskeleton interface for better comfort and usability is needed to enhance their practical application.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2021)
Letter
Surgery
V. Dronavalli, S. Clark
ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND
(2023)
Article
Cardiac & Cardiovascular Systems
Suleman Aktaa, Gorav Batra, Stefan K. James, Daniel J. Blackman, Peter F. Ludman, Mamas A. Mamas, Mohamed Abdel-Wahab, Gianni D. Angelini, Martin Czerny, Victoria Delgado, Giuseppe De Luca, Agricola Eustachio, Dan Foldager, Christian W. Hamm, Bernard Iung, Norman Mangner, Julinda Mehilli, Gavin J. Murphy, Darren Mylotte, Radoslaw Parma, Anna Sonia Petronio, Bodgan A. Popescu, Lars Sondergaard, Rui C. Teles, Manel Sabate, Christian J. Terkelsen, Luca Testa, Jianhua Wu, Aldo P. Maggioni, Lars Wallentin, Barbara Casadei, Chris P. Gale
Summary: The EuroHeart project aims to create pan-European data standards for cardiovascular diseases and interventions, including TAVI, to quantify quality of care and patient outcomes.
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2023)
Article
Cardiac & Cardiovascular Systems
James Arkley, Lay Ping Ong, Niranjan Gunaratnam, Tanveer Butt, Stephen Charles Clark
Summary: A novel distractions capture tool was used to evaluate the severity of distractions during cardiac surgery and lung transplantation. Distractions were found to be associated with bleeding, prolonged ICU stay, prolonged hospital stay, and anastomotic complications.
JOURNAL OF CARDIOTHORACIC SURGERY
(2023)
Article
Dermatology
Rhiannon C. Macefield, Jane M. Blazeby, Barnaby C. Reeves, Anni King, Jonathan Rees, Anne Pullyblank, Kerry Avery
Summary: This study developed and evaluated a method for patients to capture standardized wound images for remote wound assessment to detect surgical site infection (SSI). The results showed that the method is simple, standardized, and acceptable, and high-quality images can be used for remote assessment of SSI.
JOURNAL OF TISSUE VIABILITY
(2023)
Article
Cardiac & Cardiovascular Systems
Simon Messer, Sally Rushton, Lewis Simmonds, Debbie Macklam, Mubbasher Husain, Anand Jothidasan, Stephen Large, Steven Tsui, Pradeep Kaul, Jennifer Baxter, Mohamed Osman, Vipin Mehta, Derval Russell, Uli Stock, John Dunning, Diana Garcia Saez, Rajamiyer Venkateswaran, Philip Curry, Lynne Ayton, Majid Mukadam, Jorge Mascaro, Jacob Simmonds, Guy Macgowan, Stephen Clark, Jerome Jungschleger, Zdenka Reinhardt, Richard Quigley, Jane Speed, Jayan Parameshwar, David Jenkins, Sarah Watson, Fiona Marley, Ayesha Ali, Dale Gardiner, Antonio Rubino, Julie Whitney, Sarah Beale, Catherine Slater, Ian Currie, Liz Armstrong, Jeanette Foley, Marian Ryan, Sharon Gibson, Karen Quinn, Anna-Maria Macleod, Susan Spence, Christopher J. E. Watson, Pedro Catarino, Anthony Clarkson, John Forsythe, Derek Manas, Marius Berman
Summary: The UK conducted a national pilot program for heart transplantation using DCD hearts, retrieved using the direct procurement and perfusion technique. The outcomes showed comparable posttransplant survival rates between DCD and DBD hearts.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2023)
Article
Cardiac & Cardiovascular Systems
Jennifer Dawn Mehew, Rachel Hogg, Stephen Clark, Karthik Santhanakrishnan, Pedro Catarino, Jorge Mascaro, Ulrich Stock, John Dark
Summary: This study investigated the impact of ischemia time on survival after lung transplantation. The findings showed that when cardiopulmonary bypass was used, each hour of total ischemic time increased the hazard of death for 1-year patient survival by 13%. However, if cardiopulmonary bypass was not used, there was no significant change in mortality with increasing ischemic time.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2023)
Review
Cardiac & Cardiovascular Systems
Benjamin Milne, Tom Gilbey, Filip De Somer, Gudrun Kunst
Summary: Cardiac surgery on cardiopulmonary bypass is often accompanied by postoperative renal dysfunction, which is a common complication. Acute kidney injury (AKI) is associated with increased morbidity and mortality, and it plays a role in the development of acute and chronic kidney disease. This review examines the epidemiology of renal dysfunction after cardiac surgery, the clinical manifestations, and the potential for perfusion-based techniques to mitigate complications.
Article
Health Care Sciences & Services
Jessica Harris, Koen B. Pouwels, Thomas Johnson, Jonathan Sterne, Christalla Pithara, Kalaivani Mahadevan, Barney Reeves, Umberto Benedetto, Yoon Loke, Daniel Lasserson, Brett Doble, Noreen Hopewell-Kelly, Sabi Redwood, Sarah Wordsworth, Andrew Mumford, Chris Rogers, Maria Pufulete
Summary: This study quantified the bleeding risk among patients undergoing different antiplatelet and triple therapy regimens for percutaneous coronary intervention or coronary artery bypass grafting, as well as conservatively managed acute coronary syndrome. The results suggest that more potent dual antiplatelet therapy may increase the risk of bleeding without reducing the incidence of major adverse cardiovascular events.
HEALTH TECHNOLOGY ASSESSMENT
(2023)
Article
Respiratory System
Ahmed Al-Adhami, Mohamed Al-Aloul, Sally Rushton, Richard Damian Thompson, Martin Carby, Jordan Lordan, Stephen Clark, Helen Spencer, Steven Tsui, Jasvir Parmar
Summary: The UK Lung Allocation Scheme (UKLAS) was introduced in 2017 to replace the previous geographic allocation system. This study assessed the early impact of this scheme on waiting-list and post-transplant outcomes.
Article
Surgery
Nicholas J. S. Chilvers, Zachariah M. Evans, Sankar Balasubramanian, Denis O'Leary, Simon Ledingham, Stephen C. Clark
Summary: This article reports a rare complication - trapped prosthetic valve leaflets, and introduces a novel minimally invasive surgical approach for treating high-risk patients. This method has been proven to be effective and safe through trials.
INNOVATIONS-TECHNOLOGY AND TECHNIQUES IN CARDIOTHORACIC AND VASCULAR SURGERY
(2023)
Article
Medicine, General & Internal
Salvador Catsis, Alan R. Champneys, Rebecca Hoyle, Christine Currie, Jessica Enright, Katherine Cheema, Mike Woodall, Gianni Angelini, Ramesh Nadarajah, Chris Gale, Ben Gibbison
Summary: This study models the referral, diagnostic and treatment pathway for cardiovascular disease (CVD) in the English National Health Service (NHS) using a systems dynamics approach. The study uses routinely collected, publicly available data streams of primary and secondary care. The results show an increase in NHS CVD waiting lists in England, primarily due to restrictions in referrals from primary care.
Article
Cardiac & Cardiovascular Systems
Jeremy Chan, Arnaldo Dimagli, Tim Dong, Daniel P. Fudulu, Shubhra Sinha, Gianni D. Angelini
Summary: This study analyzed the trend and early clinical outcomes of off-pump coronary artery bypass grafting (CABG) in the UK. The results showed a decreasing trend in the use of off-pump CABG since 2008. Off-pump CABG was associated with lower in-hospital/30-day mortality, return to theatre, cerebrovascular accidents, and deep sternal wound infection compared to on-pump CABG.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Health Care Sciences & Services
Tim Dong, Shubhra Sinha, Ben Zhai, Daniel P. Fudulu, Jeremy Chan, Pradeep Narayan, Andy Judge, Massimo Caputo, Arnaldo Dimagli, Umberto Benedetto, Gianni D. Angelini
Summary: This study combines EuroSCORE I and EuroSCORE II data using ensemble learning methods to predict cardiac surgery risk. The results show that both homogeneous and heterogeneous machine learning ensembles perform better than dynamic model averaging ensembles.
Article
Cardiac & Cardiovascular Systems
Shubhra Sinha, Tim Dong, Arnaldo Dimagli, Hunaid A. Vohra, Chris Holmes, Umberto Benedetto, Gianni D. Angelini
Summary: This study systematically compared the in-hospital mortality risk prediction post-cardiac surgery using different approaches, including the EuroSCORE II, logistic regression, and various machine learning techniques. The results showed that machine learning techniques, such as XGBoost and random forest, had some statistical improvements over traditional models. However, the clinical impact of these improvements is currently modest.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Daniel P. Fudulu, Georgia R. Layton, Bao Nguyen, Shubhra Sinha, Arnaldo Dimagli, Gustavo Guida, Riccardo Abbasciano, Alessandro Viviano, Gianni D. Angelini, Mustafa Zakkar
Summary: Concomitant revascularization of coronary artery disease and aortic valvopathy can positively impact survival, but combined surgery may lead to increased adverse outcomes compared to isolated aortic valve replacement or coronary artery bypass grafting.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)