miRNA-dependent target regulation: functional characterization of single-nucleotide polymorphisms identified in genome-wide association studies of Alzheimer’s disease

Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

(2017) John P. Cogswell et al.   JOURNAL OF ALZHEIMERS DISEASE

Mutation in the 3’untranslated region of APP as a genetic determinant of cerebral amyloid angiopathy

(2015) Gaël Nicolas et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer`s Disease

(2015) Johannes Denk et al.   PLoS One

Global Analyses of the Effect of Different Cellular Contexts on MicroRNA Targeting

(2014) Jin-Wu Nam et al.   MOLECULAR CELL

MicroRNAs targeting Nicastrin regulate Aβ production and are affected by target site polymorphisms

(2014) Charlotte Delay et al.   Frontiers in Molecular Neuroscience

Alteration of the microRNA network during the progression of Alzheimer's disease

(2013) Pierre Lau et al.   EMBO Molecular Medicine

Polymorphisms in microRNA target sites influence susceptibility to schizophrenia by altering the binding of miRNAs to their targets

(2013) Yunguo Gong et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms

(2013) J. M. Shulman et al.   HUMAN MOLECULAR GENETICS

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid

(2013) Mareike Müller et al.   NEUROBIOLOGY OF AGING

A blood based 12-miRNA signature of Alzheimer disease patients

(2013) Petra Leidinger et al.   GENOME BIOLOGY

Non-coding RNAs in Alzheimer's Disease

(2012) Lin Tan et al.   MOLECULAR NEUROBIOLOGY

Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease

(2012) J-C Lambert et al.   MOLECULAR PSYCHIATRY

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Discovering Dysfunction of Multiple MicroRNAs Cooperation in Disease by a Conserved MicroRNA Co-Expression Network

(2012) Yun Xiao et al.   PLoS One

A miR-1207-5p Binding Site Polymorphism Abolishes Regulation of HBEGF and Is Associated with Disease Severity in CFHR5 Nephropathy

(2012) Gregory Papagregoriou et al.   PLoS One

Evolution of the human-specific microRNA miR-941

(2012) Hai Yang Hu et al.   Nature Communications

MicroRNA genes preferentially expressed in dendritic cells contain sites for conserved transcription factor binding motifs in their promoters

(2011) Bastiaan JH Jansen et al.   BMC GENOMICS

A Common Genetic Variant in the 3′-UTR of Vacuolar H + -ATPase ATP6V0A1 Creates a Micro-RNA Motif to Alter Chromogranin A Processing and Hypertension Risk

(2011) Zhiyun Wei et al.   Circulation-Cardiovascular Genetics

Blood serum miRNA: Non-invasive biomarkers for Alzheimer's disease

(2011) Hirosha Geekiyanage et al.   EXPERIMENTAL NEUROLOGY

Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function

(2011) Charlotte Delay et al.   Molecular Neurodegeneration

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

TargetSpy: a supervised machine learning approach for microRNA target prediction

(2010) Martin Sturm et al.   BMC BIOINFORMATICS

Single-Nucleotide Polymorphisms Inside MicroRNA Target Sites Influence Tumor Susceptibility

(2010) Milena S. Nicoloso et al.   CANCER RESEARCH

Polymorphisms inside MicroRNAs and MicroRNA Target Sites Predict Clinical Outcomes in Prostate Cancer Patients Receiving Androgen-Deprivation Therapy

(2010) B.-Y. Bao et al.   CLINICAL CANCER RESEARCH

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

miRTarBase: a database curates experimentally validated microRNA–target interactions

(2010) Sheng-Da Hsu et al.   NUCLEIC ACIDS RESEARCH

Joint Genome-Wide Profiling of miRNA and mRNA Expression in Alzheimer's Disease Cortex Reveals Altered miRNA Regulation

(2010) Juan Nunez-Iglesias et al.   PLoS One

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

(2010) Doron Betel et al.   GENOME BIOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

The Expression of MicroRNA miR-107 Decreases Early in Alzheimer's Disease and May Accelerate Disease Progression through Regulation of  -Site Amyloid Precursor Protein-Cleaving Enzyme 1

(2008) W.-X. Wang et al.   JOURNAL OF NEUROSCIENCE

MicroRNA regulation of Alzheimer's Amyloid precursor protein expression

(2008) Sébastien S. Hébert et al.   NEUROBIOLOGY OF DISEASE

miRecords: an integrated resource for microRNA-target interactions

(2008) F. Xiao et al.   NUCLEIC ACIDS RESEARCH

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression

(2008) S. S. Hebert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA target site polymorphisms and human disease

(2008) Praveen Sethupathy et al.   TRENDS IN GENETICS