Article
Clinical Neurology
Nathan Evaniew, Ganesh Swamy, W. Bradley Jacobs, Jacques Bouchard, Roger Cho, Neil A. Manson, Y. Raja Rampersaud, Jerome Paquet, Christopher S. Bailey, Michael Johnson, Najmedden Attabib, Charles G. Fisher, Greg McIntosh, Kenneth C. Thomas
Summary: This study evaluated the effects of lumbar fusion surgery for patients with back pain and degenerative disc disease in the Canadian Spine Outcomes and Research Network. Results showed significant improvement in back pain, disability, and health-related quality of life at 12 months post-surgery, with a high rate of patient satisfaction. The study suggests that surgery for this indication may provide benefit and further research is warranted.
GLOBAL SPINE JOURNAL
(2022)
Article
Orthopedics
Wenbo Xu, Bingbing Ran, Jianhui Zhao, Wenqi Luo, Rui Gu
Summary: This study aimed to investigate the incidence and risk factors for failed back surgery syndrome (FBSS) following open posterior lumbar surgery for degenerative lumbar disease (DLD). The results showed that lower preoperative pain level, hypertension, intermittent claudication, HIZ, MCs, and postoperative rehabilitation were risk factors for FBSS.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Medicine, General & Internal
Alberto Ruffilli, Marco Manzetti, Francesca Barile, Marco Ialuna, Tosca Cerasoli, Giovanni Viroli, Francesca Salamanna, Deyanira Contartese, Gianluca Giavaresi, Cesare Faldini
Summary: Proximal junctional disease (PJD) and surgical site infection (SSI) are common complications after spine surgery. This study aimed to evaluate the influence of sarcopenia and osteopenia on these complications. Preoperative MRI was used to measure central sarcopenia and osteopenia. The analysis showed that comorbidity index and dural tear were independent risk factors for SSI, while age and diabetes were risk factors for PJD. However, there was no correlation between low M-score and PLVI and a higher complications rate.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Ivar M. Austevoll, Erland Hermansen, Morten W. Fagerland, Kjersti Storheim, Jens I. Brox, Tore Solberg, Frode Rekeland, Eric Franssen, Clemens Weber, Helena Brisby, Oliver Grundnes, Knut R. H. Algaard, Tordis Boker, Hasan Banitalebi, Kari Indrekvam, Christian Hellum
Summary: A trial in Norway found that decompression surgery alone was noninferior to decompression with instrumented fusion in terms of the percentage of patients who experienced a 30% reduction in pain and disability scores over a 2-year period, with a noninferiority margin of -15 percentage points.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Medicine, General & Internal
Po-Fan Chiu, Robert Chen-Hao Chang, Yung-Chi Lai, Kuo-Chen Wu, Kuan-Pin Wang, You-Pen Chiu, Hui-Ru Ji, Chia-Hung Kao, Cheng-Di Chiu
Summary: This study aimed to develop a machine learning-based radiomic model to predict the efficacy of lumbar nucleoplasty (LNP) in patients with lumbar degenerative disc disease (LDDD) using pre-treatment imaging. The data included patient characteristics, surgical details, and pre-operative MRI results. Five machine learning models were developed by combining radiomic features and clinical parameters. The improved random forest algorithm showed the best performance in accurately predicting pain improvement. This research provides valuable information for clinical treatment and decision-making.
Article
Medicine, General & Internal
Sangbong Ko, Jaebum Kwon
Summary: Patients who undergo lumbar discectomy may experience short-term improvement in low back pain (LBP), referred buttock pain (RBP), and lower leg radiating pain (LRP) within the first 3 months postoperatively. However, the improvement in LBP may plateau after 3 months and no further improvement is observed within the first year postoperatively.
Article
Clinical Neurology
Eduard Bezuglov, Artemii Lazarev, Arseniy Petrov, Alesia Brodskaia, Anastasiya Lyubushkina, Kamila Kubacheva, Evgeny Achkasov, Vladimir Nikolenko
Summary: Elite professional soccer players have a high prevalence of asymptomatic degenerative lumbar spinal changes, which are significantly associated with age. The most common pathologic condition was disc desiccation. Age was found to be associated with degenerative changes, while weight and body mass index did not show any association.
Article
Orthopedics
A. P. Goode, R. J. Cleveland, V. B. Kraus, K. A. Taylor, S. Z. George, T. A. Schwartz, J. Renner, J. L. Huebner, J. M. Jordan, Y. M. Golightly
Summary: This study investigates the association between baseline biomarkers and longitudinal changes in disc space narrowing, vertebral osteophytes, and low back pain. The findings suggest that markers of inflammation and perceived pressure pain sensitivity are associated with the longitudinal worsening of low back pain.
OSTEOARTHRITIS AND CARTILAGE
(2023)
Review
Clinical Neurology
Sunqi Nian, Na Li, Fanyi Kong, Sheng Lu, Jiayu Chen
Summary: A systematic review and meta-analysis found that preoperative Modic changes (MC) did not significantly impact low back pain and functional outcomes in patients with lumbar disc herniation (LDH) undergoing discectomy. However, LDH patients with preoperative Modic type 1 showed worse functional status at 2-year follow-up.
Article
Computer Science, Software Engineering
A. Beulah, T. Sree Sharmila, V. K. Pramod
Summary: An automatic diagnostic system for degenerative discs was developed and tested on sagittal MR images of 93 patients, achieving a high accuracy rate. The system can serve as a helpful second opinion tool for diagnosing degenerative discs.
Article
Orthopedics
Max Jakobsson, Maria Hagstromer, Hanna Lotzke, Philip von Rosen, Mari Lundberg
Summary: This study aimed to investigate the association between preoperative pain-related psychological factors and postoperative sedentary behavior (SB) and moderate to vigorous physical activity (MVPA) in patients with low back pain (LBP) and degenerative disc disorder. The study found a significant association between preoperative fear of movement and postoperative SB.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Clinical Neurology
Matthew Scott-Young, So Mang (Simon) Lee, David Nielsen, Evelyne Rathbone, Matthew Rackham, Wayne Hing
Summary: This study aimed to compare the patient-reported outcomes of single-level total disc arthroplasty (TDA), multi-level TDA, and hybrid constructs for symptomatic degenerative disc disease. The results showed that these treatment methods achieved similar clinical and statistical results in pain and function with meticulous preoperative evaluation.
Article
Clinical Neurology
Meshal Jarebi, Aisha Awaf, Michel Lefranc, Johann Peltier
Summary: This study compared the clinical outcomes and recovery time between open lumbar microdiscectomy (OLMD) and percutaneous endoscopic lumbar discectomy (PELD). The results showed that both procedures provided similar satisfactory outcomes, but PELD demonstrated potential advantages in terms of quicker recovery and lower back pain reduction early on. Further large-scale, randomized studies with long-term follow-up are needed to confirm these findings.
Article
Radiology, Nuclear Medicine & Medical Imaging
Cecilie Lerche Nordberg, Mikael Boesen, Gilles Ludger Fournier, Henning Bliddal, Philip Hansen, Bjarke Brandt Hansen
Summary: The study revealed dynamic behavior of lumbar disc herniations with morphological changes in the standing position, resulting in exacerbated nerve root compression.
EUROPEAN RADIOLOGY
(2021)
Article
Orthopedics
Tao Zou, Hao Chen, Ping-Chuan Wang, Hui-Hui Sun, Xin-Min Feng
Summary: This study evaluated the change patterns of leg numbness (LN) after lumbar decompression surgery (LDS) and identified predictive factors for numbness recovery. The majority of patients showed significant improvement in LN within 6 months after surgery, with slower improvement in VAS-LN compared to VAS-LP. High pre-operative VAS-LN score was found to independently predict the presence of residual LN at 12-month follow-up.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Clinical Neurology
Victor E. Staartjes, Holger Joswig, Marco V. Corniola, Karl Schaller, Oliver P. Gautschi, Martin N. Stienen
Summary: The study found that medical comorbidities have a certain impact on the objective functional impairment of patients before surgery, but the association is weak and inconsistent. TUG testing may be valid even in patients with relatively severe comorbidities who are able to complete the test.
GLOBAL SPINE JOURNAL
(2022)
Article
Clinical Neurology
Harsh Wadhwa, Kunal Varshneya, Martin N. Stienen, Anand Veeravagu
Summary: This retrospective cohort study aimed to investigate the effect of preoperative epidural steroid injection (ESI) on quality outcomes and costs in patients undergoing surgery for cervical degenerative disease. The results showed that while ESI can offer pain relief, patients who eventually undergo surgery have greater healthcare resource utilization.
GLOBAL SPINE JOURNAL
(2023)
Editorial Material
Clinical Neurology
Martin N. Stienen, Yoon Ha
Article
Oncology
Nicolas R. Smoll, Zoe Brady, Katrina J. Scurrah, Choonsik Lee, Amy Berrington de Gonzalez, John D. Mathews
Summary: This study found that about 40% of brain tumors in children may be attributable to CT radiation rather than reverse causation. However, due to a relatively low rate of CT scanning in Australia, only 3.7% of all brain cancers are attributable to CT scans. The population-attributable fraction may be greater in countries with higher rates of pediatric scanning.
Article
Clinical Neurology
Johannes Goldberg, Werner J. Z'Graggen, Martin Hlavica, Mattia Branca, Serge Marbacher, Donato D'Alonzo, Javier Fandino, Martin N. Stienen, Marian C. Neidert, Jan-Karl Burkhardt, Luca Regli, Martin Seule, Michel Roethlisberger, Raphael Guzman, Daniel Walter Zumofen, Rodolfo Maduri, Roy Thomas Daniel, Amir El Rahal, Marco V. Corniola, Philippe Bijlenga, Karl Schaller, Roland Roelz, Christian Scheiwe, Mukesch Shah, Dieter Henrik Heiland, Oliver Schnell, Juergen Beck, Andreas Raabe, Christian Fung
Summary: This study collected prospective quality of life (QoL) data on survivors of poor-grade aneurysmal subarachnoid hemorrhage (aSAH) and found that despite high initial mortality, a reasonably large proportion of poor-grade aSAH survivors have good QoL.
Article
Clinical Neurology
Michal Ziga, Marketa Sosnova, Anna M. Zeitlberger, Luca Regli, Oliver Bozinov, Astrid Weyerbrock, John K. Ratliff, Martin N. Stienen, Nicolai Maldaner
Summary: This study aimed to investigate the application of a smartphone-based 6-minute walking test in patients with degenerative lumbar disorders after surgery. The study found that this test could objectively assess patients' functional impairment and detect changes in their recovery after surgery. Additionally, a ceiling effect was observed in some patients, indicating that their patient-reported outcome measures could not further improve.
Article
Clinical Neurology
Vaibhavi Shah, Adrian J. Rodrigues, Shreya Malhotra, Thomas Johnstone, Kunal Varshneya, Ghani Haider, Martin N. Stienen, Anand Veeravagu
Summary: We compared differences in postoperative complications, readmission rates, reoperation rates, lengths of hospital stay, and cost of treatment between patients with Medicare versus private insurance who underwent an anterior discectomy and fusion (ACDF) procedure. The study found that Medicare and privately insured patients had similar treatment outcomes after ACDF surgery.
WORLD NEUROSURGERY
(2023)
Article
Orthopedics
Adrian John Rodrigues, Kunal Varshneya, Martin Nikolaus Stienen, Ethan Schonfeld, Khoi Duc Than, Anand Veeravagu
Summary: This retrospective cohort study aimed to compare the outcomes and costs of ACDF procedures using synthetic biomechanical intervertebral cage (BC) and structural allograft (SA) implants. After adjusting for demographic characteristics and comorbidities, the clinical outcomes were found to be similar between BC and SA ACDF surgeries. However, physician's fees were higher for BC implantation procedures.
ASIAN SPINE JOURNAL
(2023)
Article
Orthopedics
Adrian John Rodrigues, Ethan Schonfeld, Kunal Varshneya, Martin Nikolaus Stienen, Anand Veeravagu
Summary: This retrospective cohort study aimed to compare the outcomes of anterior cervical discectomy and fusion (ACDF) in patients with and without myelopathy. The results showed that patients with myelopathy had a higher risk of reoperation and hospital readmission compared to those without myelopathy.
ASIAN SPINE JOURNAL
(2023)
Article
Medicine, General & Internal
Nicolas R. Smoll, Mahmudul Hassan Al Imam, Connie Shulz, Robert Booy, Gulam Khandaker
Summary: This study aimed to estimate the effectiveness of vaccination in protecting against hospitalisation with symptomatic COVID-19. The results showed that vaccination significantly reduced the hospitalisation rate among the population in Central Queensland, with vaccine effectiveness of 69.9% after the primary vaccination course and 81.8% after a booster dose.
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Clinical Neurology
Tarek ElFiky, Bishoy Bessada, Martin N. Stienen, Ahmed Ezzat Siam, Ahmed Hasan
Summary: This study retrospectively evaluated the MRI results of 103 patients with cervical spondylotic myelopathy (CSM). The findings showed that 71.4% of patients aged 50 or older had Modic changes (MC), with the C3-C4 segment being the most common. In contrast, 61.5% of younger patients had no MC. Degenerative changes in the facet joints were found in the majority of patients regardless of age, with grade I degeneration being the most common. The study also revealed a significant correlation between MC and facet joint changes.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Anna L. Kalywis, Robin Samuel, Felix Scholtes, Gilles Reuter, Martin N. Stienen, Erich Seifritz, Werner Surbeck
Summary: This study compared the neuroticism levels of physicians and found that although surgeons have lower levels of neuroticism in the early stages of their career, their neuroticism increases with age. This effect is especially significant for neurosurgeons.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Stefan Motov, Felix Stengel, Florian Ringel, Oliver Bozinov, Martin N. Stienen
Summary: This study aimed to understand the decision-making process of preoperative embolization (PE) for spinal metastasis in European spine centers. The results showed that PE is not routinely performed among European spine surgeons and is mostly considered for elective cases with hypervascularized tumors scheduled in a separate anesthesia <24h before tumor resection. Most participants reported reduced intraoperative blood loss, but also noted the risk of procedure-related complications.
Article
Clinical Neurology
Gregor Fischer, Vincens Kalin, Oliver P. Gautschi, Oliver Bozinov, Martin N. Stienen
Letter
Clinical Neurology
Felix C. Stengel, Oliver Bozinov, Martin N. Stienen
Article
Clinical Neurology
Guilu He, Jianhao Lin, Jing Ye, Fobao Huang, Changzhi Yan, Zesi Liu, Xiuming Zhou, Qiao Li, Liang Zhang
Summary: This article introduces long tunneled external ventricular drain (LTEVD), which effectively avoids multiple surgeries by connecting an external shunt valve. It allows visual control of drainage flow, prolongs catheter indwelling time, and eliminates the need for multiple surgeries.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Vinay Suresh, H. S. Suresh, Bharath Raju, Himanshu Jindal, Ahmad Ozair
Summary: This study investigated the outcomes of postoperative discitis treated with debridement and a novel technique focused on reducing outpatient antibiotic requirement in a low- and middle-income country (LMIC) setting. The results showed that patients with medically refractory postoperative discitis potentially have good outcomes after debridement plus 2-week local antibiotic instillation in LMICs.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Beatrice C. Bono, Davide Milani, Fabio Ferreli, Simone Olei, Luca Raspagliesi, Maria Pia Tropeano, Giovanni B. Lasio, Federico Pessina
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Avi A. Gajjar, Shrey Patel, Raj Swaroop Lavadi, Rida Mitha, Rohit Prem Kumar, Tavis Taylor, Galal A. Elsayed, D. Kojo Hamilton, Nitin Agarwal
Summary: Art in neurosurgery has played a crucial role in the discipline for centuries. Medical illustrations help visualize anatomy and surgical procedures, contributing to education, surgical planning, and navigation.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Joaquin Perez Zabala, Yamila Basilotta Marquez, Romina Arganaraz, Beatriz Mantese
Summary: We present a low-cost and easily accessible adaptation system for stereotactic procedures in infants. By using a headband cast technique, a stereotactic biopsy was successfully performed in a 5-month-old patient, achieving precise targeting, histopathological diagnosis, and no associated complications.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Muhammad Kusdiansah, Arnau Benet, Yosuke Suzuki, Kenichi Haraguchi, Nakao Ota, Kosumo Noda, Rokuya Tanikawa
Summary: Fusiform vertebral artery aneurysms are difficult to treat, and endovascular and open microsurgical treatments are used for different situations. This report presents a case with complex anatomy and branch involvement and describes the treatment strategy used.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Victor M. Lu
Summary: This review emphasizes four essential domains that should be considered when interpreting pediatric neurosurgical SRMAs and provides examples to ensure accurate and effective interpretation of findings in this niche.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Lapo Bonosi, Angelo Torrente, Filippo Brighina, Cateno Concetto Tito Petralia, Pietro Merlino, Chiara Avallone, Vincenzo Gulino, Roberta Costanzo, Lara Brunasso, Domenico Gerardo Iacopino, Rosario Maugeri
Summary: Corticocortical evoked potentials (CCEPs) have emerged as a valuable intraoperative monitoring technique in eloquent brain tumor surgery, aiding in preserving critical functional areas. Current research shows the potential of CCEPs in guiding surgical decision making, reducing the risk of postoperative neurological deficits, and mapping functional connectivity, but further research and standardization are needed.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Yuchen Duan, Dagang Feng, Min Zhu, Heng Qiu, Tong Li, Zhen Chen, Leiming Jiang, Yong Huang
Summary: This study aimed to compare the effect of different Modic changes (MC) grades on the cage subsidence rate after spinal interbody fusion surgery. A meta-analysis was conducted on relevant randomized controlled trials and cohort studies. The results showed that MC may be associated with a higher cage subsidence rate. With the increase in MC grades, the incidence of subsidence decreased gradually, but it was always higher than that in the non-Modic changes (NMC). Oblique lumbar interbody fusion may be a better treatment choice for lumbar degenerative disease with MC.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Brian F. Saway, Conor M. Cunningham, Mustafa Ismail, Alejandro M. Spiotta
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Joanna M. Roy, Michael M. Covell, Carmelo Venero Jr, Christian A. Bowers
Summary: Early exposure to neurosurgery during medical school is critical for improving recruitment into the specialty. However, about 30% of medical schools in the U.S. lack a neurosurgery program, limiting students' exposure to the field. Virtual education, facilitated by webinars during the pandemic, has advantages such as global outreach and accessibility for international medical students. This review identifies and describes 16 educational resources, serving as a guide for medical students interested in neurosurgery.
WORLD NEUROSURGERY
(2024)