Article
Medicine, General & Internal
Sally Hopewell, David J. Keene, Ioana R. Marian, Melina Dritsaki, Peter Heine, Lucy Cureton, Susan J. Dutton, Helen Dakin, Andrew Carr, Willie Hamilton, Zara Hansen, Anju Jaggi, Chris Littlewood, Karen L. Barker, Alastair Gray, Sarah E. Lamb
Summary: This study compared the clinical effectiveness and cost-effectiveness of a progressive exercise programme with physiotherapy advice for rotator cuff disorders, and found no significant difference in improvement over 12 months. Additionally, corticosteroid injections did not provide any long-term benefits to patients with rotator cuff disorders.
Review
Medicine, General & Internal
Juan G. Dominguez-Romero, Jose J. Jimenez-Rejano, Carmen Ridao-Fernandez, Gema Chamorro-Moriana
Summary: Based on a systematic review, various exercise programs were found to be effective in improving shoulder pain and function in RC tendinopathy patients. However, due to the heterogeneity of interventions, solid conclusions could not be drawn from the comparisons.
Review
Medicine, General & Internal
Teresa Paolucci, Francesco Agostini, Marco Conti, Sara Cazzolla, Elena Mussomeli, Gabriele Santilli, Federica Poso, Andrea Bernetti, Marco Paoloni, Massimiliano Mangone
Summary: The rehabilitation protocols after rotator cuff repair have different advantages. Early rehabilitation can improve range of motion in the short term, while long-term functional recovery is similar to the traditional protocol. The risk of retear remains a concern for early rehabilitation. Choosing the appropriate rehabilitation protocol based on individual needs can lead to better shoulder function recovery.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Rehabilitation
Stefanos Karanasios, Vasileios Korakakis, Afroditi Diochnou, Georgios Oikonomou, Ingrid A. Gedikoglou, George Gioftsos
Summary: This study aimed to translate and cross-culturally adapt the WORC index into Greek and evaluate its reliability and validity in a Greek population with rotator cuff disorders. The results showed excellent content and face validity, internal consistency, and test-retest reliability for the WORC-GR, with high positive correlations found with DASH and SPADI.
DISABILITY AND REHABILITATION
(2023)
Article
Orthopedics
Adam C. Abraham, Fei Fang, Mikhail Golman, Panagiotis Oikonomou, Stavros Thomopoulos
Summary: Analysis of different load-dependent rotator cuff tendinopathy models revealed that underuse and destabilization resulted in changes in forepaw weight-bearing, decreased tendon-to-bone attachment strength, and reduced tendon strength, while overuse activity caused alterations in walking patterns, increased tendon stiffness, and suppression of wound healing-related gene expression.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Review
Orthopedics
Zetao Wang, Youguo Liao, Canlong Wang, Chenqi Tang, Cailian Fang, Junchao Luo, Hengzhi Liu, Xianan Mo, Zicheng Wang, Lingfang Shen, Junjuan Wang, Xiao Chen, Zi Yin, Jianyou Li, Weiliang Shen
Summary: Rotator cuff tendinopathy is a common disorder that causes a significant burden. Although stem cell therapy has shown promising results, there are many unresolved issues, such as determining the optimal source and dosage of stem cells, as well as standardizing patient types.
JOURNAL OF ORTHOPAEDIC TRANSLATION
(2023)
Article
Orthopedics
Samuel Baek, Se-Young Ki, Seok Won Chung, Seoung-Joon Lee, Young Chang Cho, Kyung-Soo Oh
Summary: This study found that patients with RC tendinopathy exhibited delayed anticipatory muscle activation in the affected shoulder compared to the unaffected shoulder during ball catching, potentially due to central hypoexcitability.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2021)
Article
Genetics & Heredity
Kayleigh J. A. Orchard, Moeed Akbar, Lindsay A. N. Crowe, John Cole, Neal L. Millar, Stuart M. Raleigh
Summary: The development and progression of rotator cuff tendinopathy (RCT) is influenced by multiple factors, including genetics and epigenetics. This study investigated the role of histone modifications in RCT using chromatin immunoprecipitation sequencing. The findings suggest that epigenetic control, particularly through histone modifications, plays a role in the development and progression of RCT.
Review
Medicine, General & Internal
Silvia Gianola, Valerio Iannicelli, Edoardo Fascio, Anita Andreano, Linda C. Li, Maria Grazia Valsecchi, Lorenzo Moja, Greta Castellini
Summary: The use of Kinesio Taping for rotator cuff disease has uncertain effects on self-reported pain, function, pain on motion, and active range of motion when compared to sham taping or other conservative treatments due to very low certainty of evidence. However, low-certainty evidence suggests that Kinesio Taping may improve quality of life compared to conservative treatments. Evidence on adverse events was scarce and uncertain. Based on the data in this review, the evidence for the efficacy of KT seems to demonstrate little or no benefit.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Biochemistry & Molecular Biology
Yezhou Wang, Jiawei Zhang, Yuan Lin, Shi Cheng, Duanyang Wang, Man Rao, Yuheng Jiang, Xiang Huang, Ruijing Chen, Yong Xie, Pengbin Yin, Biao Cheng
Summary: Rotator cuff tendinopathy (RCT) is a common cause of shoulder pain, and understanding its mechanism and biochemical changes is crucial for developing effective therapeutic strategies. In this study, the researchers generated a protein phosphorylation atlas for RCT patients and identified numerous upregulated and downregulated phosphorylation sites and proteins. GO enrichment analysis revealed that the proteins with upregulated phosphorylation sites are mainly involved in neutrophil-mediated immunity, while those with downregulated sites are mainly associated with muscle development. Pathway analysis identified NF-kappa B-related TNF signaling pathway and PKC alpha-related Wnt signaling pathway as being associated with RCT pathology. Additionally, a weighted kinase-site phosphorylation network was constructed, and serine/threonine-protein kinase 39 (STLK3) and mammalian STE20-like protein kinase 1 (MST1) were proposed as potentially core kinases positively correlated with Wnt pathway activation.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Endocrinology & Metabolism
Kuishuai Xu, Liang Zhang, Zhongkai Ren, Tianrui Wang, Yingze Zhang, Xia Zhao, Tengbo Yu
Summary: This study established and validated a rat model of rotator cuff tendinopathy to explore the effects of type 2 diabetes on the rotator cuff tendon. The results showed that persistent type 2 diabetes is associated with collagen fiber rupture, extracellular matrix disturbance, and biomechanical decline of the rotator cuff tendon.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pharmacology & Pharmacy
Rezvaneh Mohebbi, Zahra Rezasoltani, Mahshad Mir, Maryam Mohebbi, Sima Vatandoost, Hadi Esmaily
Summary: Comparing the clinical effects of high- versus low-molecular-weight hyaluronic acid in the management of rotator cuff tendinopathy, both medications are found to be effective for the treatment, with benefits lasting at least 3 months and pain alleviation partially lasting up to 6 months. Low-molecular-weight hyaluronate is more tolerable for patients, making it the recommended choice for rotator cuff tendinopathy management.
ANNALS OF PHARMACOTHERAPY
(2021)
Article
Orthopedics
Marlis T. Sabo, Justin LeBlanc, Kevin A. Hildebrand
Summary: The study found that there were no significant differences in patient-reported outcomes between men and women undergoing rotator cuff surgery. While women were more likely to have dominant-arm surgery and had smaller rotator cuff tears than men, both groups reported high levels of satisfaction.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Health Care Sciences & Services
Ga Yang Shim, Eun Hye Kim, Yun Jeong Baek, Won Kee Chang, Bo Ram Kim, Joo Han Oh, Jong In Lee, Ji Hye Hwang, Jae-Young Lim
Summary: A digital healthcare system based on augmented reality (AR) has promising uses for postoperative rehabilitation, and can show better improvement in terms of shoulder function after rotator cuff repair (RCR) compared to conventional rehabilitation.
NPJ DIGITAL MEDICINE
(2023)
Article
Orthopedics
Umile Giuseppe Longo, Alessandro Mazzola, Simone Carotti, Maria Francesconi, Simone Catapano, Francesco Magri, Giuseppe Perrone, Sergio Morini, Sergio De Salvatore, Vincenzo Denaro
Summary: This study investigated the presence of estrogen receptors and progesterone receptor in the supraspinatus tendon of patients with RC tears, finding significantly higher expression in postmenopausal women compared to men. There were positive correlations between ER expression and age in women, as well as between ER expression and histopathological findings. The results suggest a potential role of sex hormones in the pathogenesis of RC tears.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Sport Sciences
Benjamin E. Smith, Paul Hendrick, Marcus Bateman, Sinead Holden, Chris Littlewood, Toby O. Smith, Pip Logan
BRITISH JOURNAL OF SPORTS MEDICINE
(2019)
Article
Orthopedics
Benjamin E. Smith, Paul Hendrick, Marcus Bateman, Fiona Moffatt, Michael Skovdal Rathleff, James Selfe, Toby O. Smith, Pip Logan
BMC MUSCULOSKELETAL DISORDERS
(2019)
Article
Medicine, Research & Experimental
Chris Littlewood, Marcus Bateman, Kendra Cooke, Susie Hennnings, Tina Cookson, Kieran Bromley, Martyn Lewis, Lennard Funk, Jean Denton, Maria Moffatt, Rachel Winstanley, Saurabh Mehta, Gareth Stephens, Lisa Dikomitis, Linda Chesterton, Nadine E. Foster
Article
Medicine, General & Internal
Benjamin E. Smith, Fiona Moffatt, Paul Hendrick, Marcus Bateman, James Selfe, Michael Skovdal Rathleff, Toby O. Smith, Phillipa Logan
Article
Rehabilitation
Chris Littlewood, Marcus Bateman, Stephanie Butler-Walley, Sarah Bathers, Kieran Bromley, Martyn Lewis, Lennard Funk, Jean Denton, Maria Moffatt, Rachel Winstanley, Saurabh Mehta, Gareth Stephens, Lisa Dikomitis, Nadine E. Foster
Summary: The study aimed to evaluate the feasibility of a multi-centre randomised controlled trial comparing early patient-directed rehabilitation with standard rehabilitation following rotator cuff repair surgery. Results showed a greater time out of the sling in the early patient-directed rehabilitation group, but also more full-thickness re-tears. Follow-up rates were high in both groups.
CLINICAL REHABILITATION
(2021)
Article
Medicine, Research & Experimental
Marcus Bateman, Jonathan P. Evans, Viana Vuvan, Val Jones, Adam C. Watts, Joideep Phadnis, Leanne Bisset, Bill Vicenzino
Summary: This study aims to develop a core outcome set for lateral elbow tendinopathy (LET) based on nine core tendinopathy outcome domains identified by the ICON Group. The three-phase approach includes a systematic review, matching instruments to core domains, and conducting an international Delphi study. This project will provide a minimum COS for LET research and be registered with the COMET database.
Article
Sport Sciences
Marcus Bateman, Jonathan P. Evans, Viana Vuvan, Val Jones, Adam C. Watts, Joideep Phadnis, Leanne M. Bisset, Bill Vicenzino
Summary: This study used a mixed-methods design to develop a core outcome set for lateral elbow tendinopathy (COS-LET) and provide guidance for outcome evaluation in future studies. The study identified specific instruments for different domains of tendinopathy and made interim recommendations for outcome measures. Further validation and development work is needed to capture all domains effectively.
BRITISH JOURNAL OF SPORTS MEDICINE
(2022)
Article
Orthopedics
Nestor Requejo-Salinas, Jeremy Lewis, Lori A. Michener, Roy La Touche, Ruben Fernandez-Matias, Juan Tercero-Lucas, Paula Rezende Camargo, Marcus Bateman, Filip Struyf, Jean-Sebastien Roy, Anju Jaggi, Timothy Uhl, Leanne Bisset, Craig A. Wassinger, Robert Donatelli, Melina Nevoeiro Haik, Enrique Lluch-Girbes
Summary: A Delphi study was conducted to identify the most relevant clinical descriptors for diagnosing rotator cuff related shoulder pain (RCRSP). Consensus was reached on 18 clinical descriptors across six clinical domains.
BRAZILIAN JOURNAL OF PHYSICAL THERAPY
(2022)
Article
Medicine, General & Internal
Marcus Bateman, Benjamin Saunders, Chris Littlewood, Jonathan C. Hill
Summary: This study successfully developed a physiotherapist-led treatment protocol for lateral elbow tendinopathy using an online NGT consensus approach. The optimised treatment package includes advice and education, exercise therapy, and orthotics, while excluding other treatment options like electrotherapy, acupuncture, and manual therapy. This intervention is now ready for testing in future trials to contribute much needed evidence about LET treatment.
Article
Medicine, General & Internal
Harvinder Pal Singh, Han Hong Chong, Parag Raval, Pip Divall, Amar Rangan, Marcus Bateman, Adam Watts, Joideep Phadnis, Addie Majed, Valerie Jones, Radhakant Pandey, Jonathan Gower, Steve Gwilym, Chris Peach
Summary: This study conducted a UK-based James Lind Alliance (JLA) Priority Setting Partnership for elbow conditions to identify the top 10 research priority questions. The results will guide future efforts in diagnosis, treatment, and rehabilitation of elbow conditions.
Article
Medicine, General & Internal
Marcus Bateman, Jonathan C. Hill, Karin Cooper, Chris Littlewood, Benjamin Saunders
Summary: The lived experience of people with lateral elbow tendinopathy (LET) and its impact on everyday life were explored through qualitative interviews. The study found that LET is often caused by specific activities and has significant impacts on daily tasks, sleep, work, and hobbies. People hesitated to trust online advice, were confused by the common label of 'Tennis Elbow', and perceived the wide array of healthcare treatments as ineffective.
Article
Medicine, Research & Experimental
M. Bateman, B. Saunders, C. Littlewood, D. Davis, J. Beckhelling, K. Cooper, A. Skeggs, N. E. Foster, B. Vicenzino, J. C. Hill
Summary: The study aims to test the feasibility of an optimized physiotherapy treatment package for tennis elbow, prepare for a future full-scale trial, and focus on the acceptability of the study processes and participants' treatment experiences.
PILOT AND FEASIBILITY STUDIES
(2022)
Article
Health Care Sciences & Services
Marie L. Morgan, Gareth R. Davies-Jones, Edward F. Ibrahim, Simon J. Booker, Marcus Bateman, Amol A. Tambe, David Clark
Summary: Implementing an ER programme for total shoulder arthroplasty can reduce length of hospital stay, improve patient satisfaction, and maintain complication rates, which benefits both patients and the healthcare system.
Article
Rheumatology
Chris Littlewood, Bruno Mazuquin, Maria Moffatt, Marcus Bateman
Summary: This study surveyed clinicians involved with rehabilitation following rotator cuff repair and found that for different case scenarios, the rehabilitation methods were mostly similar, with most respondents still recommending 4-6 weeks of immobilization. There were minor differences in recommendations between respondents from the United Kingdom and other regions.
MUSCULOSKELETAL CARE
(2021)
Article
Rheumatology
M. Bateman, E. Whitby, S. Kacha, E. Salt
MUSCULOSKELETAL CARE
(2018)
Article
Rehabilitation
Rose Goonan, Edward Mohandoss, Celia Marston, Jaqueline Kay, Anurika Priyanjali De Silva, Andrea B. Maier, Esmee Reijnierse, Marlena Klaic
Summary: This study evaluated the physical and functional outcomes of the 'Ending Pyjama Paralysis' intervention in geriatric rehabilitation patients. The results showed that this intervention did not lead to additional functional and physical benefits in this setting.
CLINICAL REHABILITATION
(2024)
Article
Rehabilitation
Sinikka Kilpikoski, Arja H. Hakkinen, Jussi P. Repo, Kati Kyrola, Juhani Multanen, Markku Kankaanpaa, Aki Vainionpaa, Esa-Pekka Takala, Hannu Kautiainen, Jari Ylinen
Summary: This study aimed to compare the effectiveness of a McKenzie Method intervention with guideline-based patient education in patients with sciatica. The results showed that multiple sessions of McKenzie-based back exercises combined with a patient's educational book had similar long-term effects to guideline-based advice. However, the small sample size and confounding factors limited the power of these results.
CLINICAL REHABILITATION
(2024)
Article
Rehabilitation
Margot W. M. de Waal, Michael Jansen, Loes M. Bakker, Arno J. Doornebosch, Elizabeth M. Wattel, Dennis Visser, Ewout B. Smit
Summary: The Utrecht Scale for Evaluation of Rehabilitation has been shown to be effective in evaluating physical and cognitive functioning in geriatric rehabilitation. A minimal important change of 14.5 points has been established for physical functioning.
CLINICAL REHABILITATION
(2024)