Pharmacodynamic and pharmacokinetic considerations in the treatment of critically Ill patients infected with carbapenem-resistant Enterobacteriaceae
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Title
Pharmacodynamic and pharmacokinetic considerations in the treatment of critically Ill patients infected with carbapenem-resistant Enterobacteriaceae
Authors
Keywords
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Journal
Virulence
Volume 8, Issue 4, Pages 440-452
Publisher
Informa UK Limited
Online
2016-08-10
DOI
10.1080/21505594.2016.1221021
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Note: Only part of the references are listed.- Assessment of theIn VitroActivity of Ceftazidime-Avibactam against Multidrug-Resistant Klebsiella spp. Collected in the INFORM Global Surveillance Study, 2012 to 2014
- (2016) Meredith Hackel et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2016) John E. Mazuski et al. CLINICAL INFECTIOUS DISEASES
- Ceftazidime-avibactam or best available therapy in patients with ceftazidime-resistant Enterobacteriaceae and Pseudomonas aeruginosa complicated urinary tract infections or complicated intra-abdominal infections (REPRISE): a randomised, pathogen-directed, phase 3 study
- (2016) Yehuda Carmeli et al. LANCET INFECTIOUS DISEASES
- Fosfomycin for Multidrug Treatment of Klebsiella pneumoniae Carbapenemase Bacteremia
- (2015) Juliana M. Kyle et al. ANNALS OF PHARMACOTHERAPY
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- (2015) Romney M. Humphries et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- The β-Lactams Strike Back: Ceftazidime-Avibactam
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- (2014) K. Phe et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2014) Shawn H. MacVane et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2014) N. Grégoire et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Carbapenemase-Producing Klebsiella pneumoniae Bloodstream Infections: Lowering Mortality by Antibiotic Combination Schemes and the Role of Carbapenems
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- Colistin and Polymyxin B: Peas in a Pod, or Chalk and Cheese?
- (2014) R. L. Nation et al. CLINICAL INFECTIOUS DISEASES
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- (2014) L.S. Tzouvelekis et al. CLINICAL MICROBIOLOGY AND INFECTION
- Tigecycline therapy for carbapenem-resistant Klebsiella pneumoniae (CRKP) bacteriuria leads to tigecycline resistance
- (2014) D. van Duin et al. CLINICAL MICROBIOLOGY AND INFECTION
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- Carbapenemases in Klebsiella pneumoniae and Other Enterobacteriaceae: an Evolving Crisis of Global Dimensions
- (2012) L. S. Tzouvelekis et al. CLINICAL MICROBIOLOGY REVIEWS
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- (2012) Phillip J. Bergen et al. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
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- Colistin pharmacokinetics in intensive care unit patients on continuous venovenous haemodiafiltration: an observational study
- (2012) N. Markou et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Avibactam is a covalent, reversible, non- -lactam -lactamase inhibitor
- (2012) D. E. Ehmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2011) Phillip J Bergen et al. CURRENT OPINION IN PHARMACOLOGY
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- (2011) Z. Aktaş et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
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- (2011) Argyris S. Michalopoulos et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
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- (2010) T. Stachyra et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2009) A. Endimiani et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2009) M. Popovic et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Tigecycline possibly underdosed for the treatment of pneumonia: a pharmacokinetic viewpoint
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- (2009) Nikos Roussos et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
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