The iron homeostasis network and hepatitis C virus – a new challenge in the era of directly acting antivirals

Direct-acting antiviral agents for hepatitis C: structural and mechanistic insights

(2016) Matthias Götte et al.   Nature Reviews Gastroenterology & Hepatology

Alterations in the iron homeostasis network: A driving force for macrophage-mediated hepatitis C virus persistency

(2016) Pelagia Foka et al.   Virulence

Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015)   LANCET

Extrahepatic manifestations of chronic hepatitis C virus infection

(2014) Patrice Cacoub et al.   DIGESTIVE AND LIVER DISEASE

Association of Hepcidin mRNA Expression With Hepatocyte Iron Accumulation and Effects of Antiviral Therapy in Chronic Hepatitis C Infection

(2014) Katarzyna Sikorska et al.   Hepatitis Monthly

Virology and cell biology of the hepatitis C virus life cycle – An update

(2014) Jean Dubuisson et al.   JOURNAL OF HEPATOLOGY

Hepatitis C vaccine

(2014) Ramesh Verma et al.   Human Vaccines & Immunotherapeutics

An Epidemiologic Update on Hepatitis C Infection in Persons Living With or at Risk of HIV Infection

(2013) Arthur Y. Kim et al.   JOURNAL OF INFECTIOUS DISEASES

Global control of hepatitis C: where challenge meets opportunity

(2013) David L Thomas   NATURE MEDICINE

Hepcidin and iron homeostasis

(2012) Tomas Ganz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Innate immunity and HCV

(2012) Markus H. Heim   JOURNAL OF HEPATOLOGY

Iron Regulator Hepcidin Exhibits Antiviral Activity against Hepatitis C Virus

(2012) Hongyan Liu et al.   PLoS One

Modulation of hepatitis C virus replication by iron and hepcidin in Huh7 hepatocytes

(2011) G. Bartolomei et al.   JOURNAL OF GENERAL VIROLOGY

Iron inhibits replication of infectious hepatitis C virus in permissive Huh7.5.1 cells

(2010) Carine Fillebeen et al.   JOURNAL OF HEPATOLOGY

A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication

(2009) Andrew W. Tai et al.   Cell Host & Microbe

Reduced serum hepcidin levels in patients with chronic hepatitis C

(2009) Domenico Girelli et al.   JOURNAL OF HEPATOLOGY

Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity

(2008) Kouichi Miura et al.   HEPATOLOGY

Patients with chronic hepatitis C achieving a sustained virological response to peginterferon and ribavirin therapy recover from impaired hepcidin secretion

(2008) Naoki Fujita et al.   JOURNAL OF HEPATOLOGY

Hepatitis C Virus–Induced Reactive Oxygen Species Raise Hepatic Iron Level in Mice by Reducing Hepcidin Transcription

(2007) Sohji Nishina et al.   GASTROENTEROLOGY