Characterization of Discrete Phosphopantetheinyl Transferases in Streptomyces tsukubaensis L19 Unveils a Complicate Phosphopantetheinylation Network

An acyltransferase domain of FK506 polyketide synthase recognizing both an acyl carrier protein and coenzyme A as acyl donors to transfer allylmalonyl and ethylmalonyl units

(2015) Hui Jiang et al.   FEBS Journal

Two Bacterial Group II Phosphopantetheinyl Transferases Involved in Both Primary Metabolism and Secondary Metabolism

(2014) Yue-Yue Wang et al.   CURRENT MICROBIOLOGY

A Single Sfp-Type Phosphopantetheinyl Transferase Plays a Major Role in the Biosynthesis of PKS and NRPS Derived Metabolites in Streptomyces ambofaciens ATCC23877

(2014) Robert Bunet et al.   PLoS One

Characterization and Evolutionary Implications of the Triad Asp-Xxx-Glu in Group II Phosphopantetheinyl Transferases

(2014) Yue-Yue Wang et al.   PLoS One

Biochemical Characterization of a Malonyl-Specific Acyltransferase Domain of FK506 Biosynthetic Polyketide Synthase

(2014) Yue-Yue Wang et al.   PROTEIN AND PEPTIDE LETTERS

Improvement of Natamycin Production by Engineering of Phosphopantetheinyl Transferases in Streptomyces chattanoogensis L10

(2013) Hui Jiang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Trends in the biosynthesis and production of the immunosuppressant tacrolimus (FK506)

(2013) Carlos Barreiro et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life

(2013) Joris Beld et al.   NATURAL PRODUCT REPORTS

Analysis ofStreptomyces coelicolorPhosphopantetheinyl Transferase, AcpS, Reveals the Basis for Relaxed Substrate Specificity

(2011) Patrick Dall’Aglio et al.   BIOCHEMISTRY

Origin of the Allyl Group in FK506 Biosynthesis

(2010) Dušan Goranovič et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis of the Allylmalonyl-CoA Extender Unit for the FK506 Polyketide Synthase Proceeds through a Dedicated Polyketide Synthase and Facilitates the Mutasynthesis of Analogues

(2010) SangJoon Mo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Synechocystis sp. PCC6803 Sfp-Type Phosphopantetheinyl Transferase Does Not Possess Characteristic Broad-Range Activity

(2009) Alexandra A. Roberts et al.   CHEMBIOCHEM

Two Functionally Redundant Sfp‐Type 4′‐Phosphopantetheinyl Transferases Differentially Activate Biosynthetic Pathways inMyxococcus xanthus

(2008) Peter Meiser et al.   CHEMBIOCHEM

Evidence for a novel phosphopantetheinyl transferase domain in the polyketide synthase for enediyne biosynthesis

(2008) Elavazhagan Murugan et al.   FEBS LETTERS

Role of Phosphopantetheinyl Transferase Genes in Antibiotic Production by Streptomyces coelicolor

(2008) Y.-W. Lu et al.   JOURNAL OF BACTERIOLOGY

A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis

(2008) J. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA