The Wnt/β-catenin signaling/Id2 cascade mediates the effects of hypoxia on the hierarchy of colorectal-cancer stem cells

Hypoxia-Inducible Factors Modulate the Stemness and Malignancy of Colon Cancer Cells by Playing Opposite Roles in Canonical Wnt Signaling

(2014) Paula Santoyo-Ramos et al.   PLoS One

Chronic hypoxia induces the activation of the Wnt/β-catenin signaling pathway and stimulates hippocampal neurogenesis in wild-type and APPswe-PS1ΔE9 transgenic mice in vivo

(2014) Lorena Varela-Nallar et al.   Frontiers in Cellular Neuroscience

Wnt/β-catenin signaling enhances hypoxia-induced epithelial–mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling

(2013) Qi Zhang et al.   CARCINOGENESIS

ID1 and ID3 Regulate the Self-Renewal Capacity of Human Colon Cancer-Initiating Cells through p21

(2012) Catherine A. O'Brien et al.   CANCER CELL

High aldehyde dehydrogenase activity enhances stem cell features in breast cancer cells by activating hypoxia-inducible factor-2α

(2012) Ran-Ju Kim et al.   CANCER LETTERS

Myeloid cell leukemia-1 is a key molecular target for mithramycin A-induced apoptosis in androgen-independent prostate cancer cells and a tumor xenograft animal model

(2012) Eun-Sun Choi et al.   CANCER LETTERS

Cancer Stem Cells: Current Status and Evolving Complexities

(2012) Jane E. Visvader et al.   Cell Stem Cell

Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications

(2012) Liuqi Yang et al.   EXPERIMENTAL CELL RESEARCH

HIF-1α Confers Aggressive Malignant Traits on Human Tumor Cells Independent of Its Canonical Transcriptional Function

(2011) Young-Gun Yoo et al.   CANCER RESEARCH

Hypoxia inducible factors in cancer stem cells

(2010) J M Heddleston et al.   BRITISH JOURNAL OF CANCER

Id2 Promotes Tumor Cell Migration and Invasion through Transcriptional Repression of Semaphorin 3F

(2010) Silvia Coma et al.   CANCER RESEARCH

The Wnt/β-catenin pathway regulates growth and maintenance of colonospheres

(2010) Shailender S Kanwar et al.   Molecular Cancer

Acute Myeloid Leukemia and the Wnt Pathway

(2010) Connie J. Eaves et al.   NEW ENGLAND JOURNAL OF MEDICINE

Wnt signaling in stem and cancer stem cells

(2010) Peter Wend et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Id2 promotes the invasive growth of MCF-7 and SKOV-3 cells by a novel mechanism independent of dimerization to basic helix-loop-helix factors

(2009) Yuanguang Meng et al.   BMC CANCER

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

Wnt signaling activation and mammary gland hyperplasia in MMTV–LRP6 transgenic mice: implication for breast cancer tumorigenesis

(2009) J Zhang et al.   ONCOGENE

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

(2008) L. Du et al.   CLINICAL CANCER RESEARCH

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute

Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver

(2008) M J Gray et al.   ONCOGENE

Hypoxia and Aggressive Tumor Phenotype: Implications for Therapy and Prognosis

(2008) P. Vaupel   ONCOLOGIST

The helix-loop-helix protein Id2 is expressed differentially and induced by myc in T-cell lymphomas

(2007) Claudiu V. Cotta et al.   CANCER