Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment

Wnt co-receptor LRP5/6 overexpression confers protection against hydrogen peroxide-induced neurotoxicity and reduces tau phosphorylation in SH-SY5Y cells

(2015) Luqi Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

LRP5/6 directly bind to Frizzled and prevent Frizzled-regulated tumour metastasis

(2015) Dan-ni Ren et al.   Nature Communications

Evidence of a novel role for Pygopus in rRNA transcription

(2013) Phillip G. P. Andrews et al.   BIOCHEMICAL JOURNAL

Abnormal expression of Pygopus 2 correlates with a malignant phenotype in human lung cancer

(2013) Yang Liu et al.   BMC CANCER

Association of PYGO2 and EGFR in esophageal squamous cell carcinoma

(2013) Meysam Moghbeli et al.   MEDICAL ONCOLOGY

Wnt/β-Catenin Signaling Pathway Upregulates c-Myc Expression to Promote Cell Proliferation of P19 Teratocarcinoma Cells

(2012) Shuai Zhang et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

A Protein Array Screen for Kaposi's Sarcoma-Associated Herpesvirus LANA Interactors Links LANA to TIP60, PP2A Activity, and Telomere Shortening

(2012) M. Shamay et al.   JOURNAL OF VIROLOGY

The Wnt/β-catenin pathway drives increased cyclin D1 levels in lymph node metastasis in papillary thyroid cancer

(2011) Jingdong Zhang et al.   HUMAN PATHOLOGY

Decreased pygopus 2 expression suppresses glioblastoma U251 cell growth

(2010) Zhan-xiang Wang et al.   JOURNAL OF NEURO-ONCOLOGY

Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation

(2009) Bingnan Gu et al.   JOURNAL OF CELL BIOLOGY

β-Catenin hits chromatin: regulation of Wnt target gene activation

(2009) Christian Mosimann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Canonical WNT signalling determines lineage specificity in Wilms tumour

(2009) R Fukuzawa et al.   ONCOGENE

Oncogenic Activation of the Human Pygopus2 Promoter by E74-Like Factor-1

(2008) P. G.P. Andrews et al.   MOLECULAR CANCER RESEARCH

Decoding of Methylated Histone H3 Tail by the Pygo-BCL9 Wnt Signaling Complex

(2008) Marc Fiedler et al.   MOLECULAR CELL