Systematic Analysis of Drug Targets Confirms Expression in Disease-Relevant Tissues

A comparative study of disease genes and drug targets in the human protein interactome

(2015) Jingchun Sun et al.   BMC BIOINFORMATICS

The human transcriptome across tissues and individuals

(2015) M. Mele et al.   SCIENCE

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

A draft map of the human proteome

(2014) Min-Sik Kim et al.   NATURE

Novelty in the target landscape of the pharmaceutical industry

(2013) Pankaj Agarwal et al.   NATURE REVIEWS DRUG DISCOVERY

Enhancing the Prioritization of Disease-Causing Genes through Tissue Specific Protein Interaction Networks

(2012) Oded Magger et al.   PLoS Computational Biology

Trends in the exploitation of novel drug targets

(2011) Mathias Rask-Andersen et al.   NATURE REVIEWS DRUG DISCOVERY

Disease Ontology: a backbone for disease semantic integration

(2011) L. M. Schriml et al.   NUCLEIC ACIDS RESEARCH

The dysregulation of intracellular calcium in Alzheimer disease

(2010) Charlene Supnet et al.   CELL CALCIUM

Sympathetic and haemodynamic responses to lipids in healthy human ageing

(2010) John P. Florian et al.   EXPERIMENTAL PHYSIOLOGY

Sympathetic Nervous System Overactivity and Its Role in the Development of Cardiovascular Disease

(2010) Simon C. Malpas   PHYSIOLOGICAL REVIEWS

Conserved principles of mammalian transcriptional regulation revealed by RNA half-life

(2009) Caroline C. Friedel et al.   NUCLEIC ACIDS RESEARCH

A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes

(2008) K. Lage et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA