Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch
Authors
Keywords
-
Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-08-02
DOI
10.1038/srep30903
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4
- (2016) Bruno Di Stefano et al. NATURE CELL BIOLOGY
- A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC
- (2015) Helai P. Mohammad et al. CANCER CELL
- Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency
- (2015) Davide Cacchiarelli et al. CELL
- Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming
- (2015) Yasong Wu et al. NATURE CELL BIOLOGY
- LSD1 sustains pancreatic cancer growth via maintaining HIF1α-dependent glycolytic process
- (2014) Yi Qin et al. CANCER LETTERS
- Hypoxia-Inducible Factors Have Distinct and Stage-Specific Roles during Reprogramming of Human Cells to Pluripotency
- (2014) Julie Mathieu et al. Cell Stem Cell
- LSD1 promotes oxidative metabolism of white adipose tissue
- (2014) Delphine Duteil et al. Nature Communications
- Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation
- (2014) Hongmei Zhang et al. Protein & Cell
- The histone LSD1 demethylase in stemness and cancer transcription programs
- (2013) Stefano Amente et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Transient Activation of Autophagy via Sox2-Mediated Suppression of mTOR Is an Important Early Step in Reprogramming to Pluripotency
- (2013) Shuo Wang et al. Cell Stem Cell
- Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT–MET mechanism for optimal reprogramming
- (2013) Xiaopeng Liu et al. NATURE CELL BIOLOGY
- Vitamin C modulates TET1 function during somatic cell reprogramming
- (2013) Jiekai Chen et al. NATURE GENETICS
- Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds
- (2013) P. Hou et al. SCIENCE
- HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1-3 and PKM2
- (2013) Alessandro Prigione et al. STEM CELLS
- Pluripotent Stem Cell Protein Sox2 Confers Sensitivity to LSD1 Inhibition in Cancer Cells
- (2013) Xiaoming Zhang et al. Cell Reports
- Enhancer decommissioning by LSD1 during embryonic stem cell differentiation
- (2012) Warren A. Whyte et al. NATURE
- H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs
- (2012) Jiekai Chen et al. NATURE GENETICS
- Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells
- (2011) Quan Wang et al. CELL RESEARCH
- Oct4 links multiple epigenetic pathways to the pluripotency network
- (2011) Junjun Ding et al. CELL RESEARCH
- Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape
- (2011) Bernadett Papp et al. CELL RESEARCH
- Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A
- (2011) Todd S. Macfarlan et al. GENES & DEVELOPMENT
- LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells
- (2011) Antonio Adamo et al. NATURE CELL BIOLOGY
- RCOR2 Is a Subunit of the LSD1 Complex That Regulates ESC Property and Substitutes for SOX2 in Reprogramming Somatic Cells to Pluripotency
- (2011) Peng Yang et al. STEM CELLS
- Demethylation of RB Regulator MYPT1 by Histone Demethylase LSD1 Promotes Cell Cycle Progression in Cancer Cells
- (2010) H.-S. Cho et al. CANCER RESEARCH
- Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming
- (2010) Payman Samavarchi-Tehrani et al. Cell Stem Cell
- A High Proliferation Rate Is Required for Cell Reprogramming and Maintenance of Human Embryonic Stem Cell Identity
- (2010) Sergio Ruiz et al. CURRENT BIOLOGY
- Lysine-Specific Demethylase 1 Regulates the Embryonic Transcriptome and CoREST Stability
- (2010) C. T. Foster et al. MOLECULAR AND CELLULAR BIOLOGY
- Lysine Methylation Regulates E2F1-Induced Cell Death
- (2010) Haroula Kontaki et al. MOLECULAR CELL
- Phosphorylation of histone H3T6 by PKCβI controls demethylation at histone H3K4
- (2010) Eric Metzger et al. NATURE
- Role of the Murine Reprogramming Factors in the Induction of Pluripotency
- (2009) Rupa Sridharan et al. CELL
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Pscan: finding over-represented transcription factor binding site motifs in sequences from co-regulated or co-expressed genes
- (2009) Federico Zambelli et al. NUCLEIC ACIDS RESEARCH
- Dissecting direct reprogramming through integrative genomic analysis
- (2008) Tarjei S. Mikkelsen et al. NATURE
- Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells
- (2008) Jiancong Liang et al. NATURE CELL BIOLOGY
- The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation
- (2008) Jing Wang et al. NATURE GENETICS
- Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition
- (2008) Jose Silva et al. PLOS BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation