Targeting multiple response regulators of Mycobacterium tuberculosis augments the host immune response to infection

The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence

(2015) Benjamin K. Johnson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

EspR, a regulator of the ESX-1 secretion system in Mycobacterium tuberculosis, is directly regulated by the two-component systems MprAB and PhoPR

(2015) Guangxiang Cao et al.   MICROBIOLOGY-SGM

MtrA, an essential response regulator of the MtrAB two-component system, regulates the transcription of resuscitation-promoting factor B of Mycobacterium tuberculosis

(2015) Arun Kumar Sharma et al.   MICROBIOLOGY-SGM

Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion

(2014) Jan Rybniker et al.   Cell Host & Microbe

A Specific Polymorphism in Mycobacterium tuberculosis H37Rv Causes Differential ESAT-6 Expression and Identifies WhiB6 as a Novel ESX-1 Component

(2014) Luis Solans et al.   INFECTION AND IMMUNITY

Take five — Type VII secretion systems of Mycobacteria

(2013) Edith N.G. Houben et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Polyphosphate kinase 1, a central node in the stress response network of Mycobacterium tuberculosis, connects the two-component systems MprAB and SenX3-RegX3 and the extracytoplasmic function sigma factor, sigma E

(2013) S. Sanyal et al.   MICROBIOLOGY-SGM

Host Cell Autophagy Activated by Antibiotics Is Required for Their Effective Antimycobacterial Drug Action

(2012) Jwa-Jin Kim et al.   Cell Host & Microbe

MprAB Regulates the espA Operon in Mycobacterium tuberculosis and Modulates ESX-1 Function and Host Cytokine Response

(2012) X. Pang et al.   JOURNAL OF BACTERIOLOGY

Structure of the Response Regulator PhoP fromMycobacterium tuberculosisReveals a Dimer through the Receiver Domain

(2011) Smita Menon et al.   BIOCHEMISTRY

Histidine kinases and response regulators in networks

(2011) Kirsten Jung et al.   CURRENT OPINION IN MICROBIOLOGY

The prrAB Two-Component System Is Essential for Mycobacterium tuberculosis Viability and Is Induced under Nitrogen-Limiting Conditions

(2011) S. E. Haydel et al.   JOURNAL OF BACTERIOLOGY

Adaptation to Environmental Stimuli within the Host: Two-Component Signal Transduction Systems of Mycobacterium tuberculosis

(2011) D. J. Bretl et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Control of CydB and GltA1 Expression by the SenX3 RegX3 Two Component Regulatory System of Mycobacterium tuberculosis

(2011) Gretta Roberts et al.   PLoS One

Bacterial Sensor Kinases: Diversity in the Recognition of Environmental Signals

(2010) Tino Krell et al.   Annual Review of Microbiology

Role of autophagy in the host response to microbial infection and potential for therapy

(2010) Mario Fabri et al.   CURRENT OPINION IN IMMUNOLOGY

Mycobacterium tuberculosisOrigin of Replication and the Promoter for Immunodominant Secreted Antigen 85B Are the Targets of MtrA, the Essential Response Regulator

(2010) Malini Rajagopalan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphate Depletion: A Novel Trigger forMycobacterium tuberculosisPersistence

(2009) Dalin Rifat et al.   JOURNAL OF INFECTIOUS DISEASES

A replication clock for Mycobacterium tuberculosis

(2009) Wendy P Gill et al.   NATURE MEDICINE

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

(2008) L. E. Via et al.   INFECTION AND IMMUNITY

Secreted transcription factor controls Mycobacterium tuberculosis virulence

(2008) Sridharan Raghavan et al.   NATURE

PhoP: A Missing Piece in the Intricate Puzzle of Mycobacterium tuberculosis Virulence

(2008) Jesús Gonzalo-Asensio et al.   PLoS One