Pharmacokinetics and tolerability of NSC23925b, a novel P-glycoprotein inhibitor: preclinical study in mice and rats

Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of Encenicline, a Selective α7 Nicotinic Receptor Partial Agonist, in Single Ascending-dose and Bioavailability Studies

(2015) Ann J. Barbier et al.   CLINICAL THERAPEUTICS

NSC23925 prevents the emergence of multidrug resistance in ovarian cancer in vitro and in vivo

(2015) Xiaoqian Yang et al.   GYNECOLOGIC ONCOLOGY

Nsc23925 prevents the development of paclitaxel resistance by inhibiting the introduction of P-glycoprotein and enhancing apoptosis

(2015) Xiaoqian Yang et al.   INTERNATIONAL JOURNAL OF CANCER

Prevention of multidrug resistance (MDR) in osteosarcoma by NSC23925

(2014) X Yang et al.   BRITISH JOURNAL OF CANCER

Preclinical Pharmacokinetics, Tolerability, and Pharmacodynamics of Metuzumab, a Novel CD147 Human-Mouse Chimeric and Glycoengineered Antibody

(2014) Z. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Preclinical Pharmacological Evaluation of a Novel Multiple Kinase Inhibitor, ON123300, in Brain Tumor Models

(2014) X. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Time-Dependent Interaction of Ritonavir in Chronic Use: The Power Balance Between Inhibition and Induction of P-Glycoprotein and Cytochrome P450 3A

(2013) Keizo Fukushima et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Synthesis and Evaluation of (2-(4-Methoxyphenyl)-4-quinolinyl)(2-piperidinyl)methanol (NSC23925) Isomers To Reverse Multidrug Resistance in Cancer

(2012) Zhenfeng Duan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Improving Cancer Chemotherapy with Modulators of ABC Drug Transporters

(2011) S. Shukla et al.   CURRENT DRUG TARGETS

Computational models for predicting substrates or inhibitors of P-glycoprotein

(2011) Lei Chen et al.   DRUG DISCOVERY TODAY

P-glycoprotein Substrate Models Using Support Vector Machines Based on a Comprehensive Data set

(2011) Zhi Wang et al.   Journal of Chemical Information and Modeling

Interaction of Tyrosine Kinase Inhibitors with the MDR-Related ABC Transporter Proteins

(2010) Xiao-Kun Wang et al.   CURRENT DRUG METABOLISM

Effects of Drug Transporters on Volume of Distribution

(2009) Anita Grover et al.   AAPS Journal

A Phase I Study of the P-Glycoprotein Antagonist Tariquidar in Combination with Vinorelbine

(2009) J. Abraham et al.   CLINICAL CANCER RESEARCH

NSC23925, Identified in a High-Throughput Cell-Based Screen, Reverses Multidrug Resistance

(2009) Zhenfeng Duan et al.   PLoS One

Resistance to Chemotherapy in Cancer: A Complex and Integrated Cellular Response

(2008) Howard R. Mellor et al.   PHARMACOLOGY