A minimal conformational switching-dependent model for amyloid self-assembly

An Early Folding Contact between Phe19 and Leu34 is Critical for Amyloid-β Oligomer Toxicity

(2015) Anand K. Das et al.   ACS Chemical Neuroscience

Single Fibril Growth Kinetics of α-Synuclein

(2015) Michael M. Wördehoff et al.   JOURNAL OF MOLECULAR BIOLOGY

Fragmentation of Amyloid Fibrils Occurs in Preferential Positions Depending on the Environmental Conditions

(2015) Lucrèce Nicoud et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Layers of structure and function in protein aggregation

(2015) Motomasa Tanaka et al.   Nature Chemical Biology

Force generation by the growth of amyloid aggregates

(2015) Therese W. Herling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytotoxic Helix-Rich Oligomer Formation by Melittin and Pancreatic Polypeptide

(2015) Pradeep K. Singh et al.   PLoS One

Elucidating the Role of Disulfide Bond on Amyloid Formation and Fibril Reversibility of Somatostatin-14

(2014) Arunagiri Anoop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polymorphism in Self-Assembly of Peptide-Based β-Hairpin Contributes to Network Morphology and Hydrogel Mechanical Rigidity

(2014) Yifat Miller et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Crucial role of nonspecific interactions in amyloid nucleation

(2014) Anđela Šarić et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Amyloid Formation by Glucagon-Like Peptides: Role of Basic Residues in Heparin-Mediated Aggregation

(2013) Narendra Nath Jha et al.   BIOCHEMISTRY

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Time evolution of amyloid fibril length distribution described by a population balance model

(2012) Paolo Arosio et al.   CHEMICAL ENGINEERING SCIENCE

From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation

(2012) Samuel I.A. Cohen et al.   JOURNAL OF MOLECULAR BIOLOGY

Oligomeric Intermediates in Amyloid Formation: Structure Determination and Mechanisms of Toxicity

(2012) Marcus Fändrich   JOURNAL OF MOLECULAR BIOLOGY

Connecting Macroscopic Observables and Microscopic Assembly Events in Amyloid Formation Using Coarse Grained Simulations

(2012) Noah S. Bieler et al.   PLoS Computational Biology

What Drives Amyloid Molecules To Assemble into Oligomers and Fibrils?

(2011) Jeremy D. Schmit et al.   BIOPHYSICAL JOURNAL

Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments

(2011) Samuel I. A. Cohen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nature of the Amyloid-β Monomer and the Monomer-Oligomer Equilibrium

(2011) Suman Nag et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metastability of Native Proteins and the Phenomenon of Amyloid Formation

(2011) Andrew J. Baldwin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Environmental Conditions Affect the Kinetics of Nucleation of Amyloid Fibrils and Determine Their Morphology

(2010) Bertrand Morel et al.   BIOPHYSICAL JOURNAL

Elucidation of Amyloid β-Protein Oligomerization Mechanisms: Discrete Molecular Dynamics Study

(2010) B. Urbanc et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ion mobility–mass spectrometry reveals a conformational conversion from random assembly to β-sheet in amyloid fibril formation

(2010) Christian Bleiholder et al.   Nature Chemistry

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stop-and-go kinetics in amyloid fibrillation

(2010) Jesper Ferkinghoff-Borg et al.   PHYSICAL REVIEW E

Biology of Amyloid: Structure, Function, and Regulation

(2010) Jason Greenwald et al.   STRUCTURE

Nonequilibrium Self-Assembly of a Filament Coupled to ATP/GTP Hydrolysis

(2009) Padinhateeri Ranjith et al.   BIOPHYSICAL JOURNAL

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

(2009) Summer L. Bernstein et al.   Nature Chemistry

Structure-neurotoxicity relationships of amyloid  -protein oligomers

(2009) K. Ono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Analytical Solution to the Kinetics of Breakable Filament Assembly

(2009) T. P. J. Knowles et al.   SCIENCE

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

Fitting Yeast and Mammalian Prion Aggregation Kinetic Data with the Finke−Watzky Two-Step Model of Nucleation and Autocatalytic Growth†

(2008) Murielle A. Watzky et al.   BIOCHEMISTRY

Fitting Neurological Protein Aggregation Kinetic Data via a 2-Step, Minimal/“Ockham's Razor” Model:  The Finke−Watzky Mechanism of Nucleation Followed by Autocatalytic Surface Growth†

(2008) Aimee M. Morris et al.   BIOCHEMISTRY

All-Atom Computer Simulations of Amyloid Fibrils Disaggregation

(2008) Jun Wang et al.   BIOPHYSICAL JOURNAL

Molecular dynamics simulations of alanine rich β-sheet oligomers: Insight into amyloid formation

(2002) Buyong Ma et al.   PROTEIN SCIENCE