Mechanistic insights into the recognition of 5-methylcytosine oxidation derivatives by the SUVH5 SRA domain

Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI

(2015) Giedrius Sasnauskas et al.   NUCLEIC ACIDS RESEARCH

Determination of Oxidation Products of 5-Methylcytosine in Plants by Chemical Derivatization Coupled with Liquid Chromatography/Tandem Mass Spectrometry Analysis

(2014) Yang Tang et al.   ANALYTICAL CHEMISTRY

Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2

(2014) Ting Zhou et al.   MOLECULAR CELL

Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE

(2014) Jiamu Du et al.   MOLECULAR CELL

5-Formylcytosine alters the structure of the DNA double helix

(2014) Eun-Ang Raiber et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of the 5hmC specific endonuclease PvuRts1I

(2014) Asgar Abbas Kazrani et al.   NUCLEIC ACIDS RESEARCH

Structure of 5-hydroxymethylcytosine-specific restriction enzyme, AbaSI, in complex with DNA

(2014) John R. Horton et al.   NUCLEIC ACIDS RESEARCH

Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix

(2014) John R. Horton et al.   NUCLEIC ACIDS RESEARCH

Structure and mutagenesis of the DNA modification-dependent restriction endonuclease AspBHI

(2014) John R. Horton et al.   Scientific Reports

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

(2013) Cornelia G. Spruijt et al.   CELL

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation

(2012) Hideharu Hashimoto et al.   NUCLEIC ACIDS RESEARCH

The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine

(2012) Rasa Sukackaite et al.   NUCLEIC ACIDS RESEARCH

Salt Stress Induced Variation in DNA Methylation Pattern and Its Influence on Gene Expression in Contrasting Rice Genotypes

(2012) Ratna Karan et al.   PLoS One

Heterologous expression and purification of Arabidopsis thaliana VIM1 protein: In vitro evidence for its inability to recognize hydroxymethylcytosine, a rare base in Arabidopsis DNA

(2012) Qin Yao et al.   PROTEIN EXPRESSION AND PURIFICATION

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Epigenetic modifications in plants: an evolutionary perspective

(2011) Suhua Feng et al.   CURRENT OPINION IN PLANT BIOLOGY

A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo

(2011) E. Rajakumara et al.   GENES & DEVELOPMENT

Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine

(2011) Atanu Maiti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recognition of 5-Hydroxymethylcytosine by the Uhrf1 SRA Domain

(2011) Carina Frauer et al.   PLoS One

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

(2011) Y.-F. He et al.   SCIENCE

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Detection of Damaged DNA Bases by DNA Glycosylase Enzymes

(2010) Joshua I. Friedman et al.   BIOCHEMISTRY

Drought-induced site-specific DNA methylation and its association with drought tolerance in rice (Oryza sativa L.)

(2010) Wen-Sheng Wang et al.   JOURNAL OF EXPERIMENTAL BOTANY

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

(2010) Julie A. Law et al.   NATURE REVIEWS GENETICS

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Damage Detection and Base Flipping in Direct DNA Alkylation Repair

(2009) Cai-Guang Yang et al.   CHEMBIOCHEM

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Structure and Hemimethylated CpG Binding of the SRA Domain from Human UHRF1

(2008) Chengmin Qian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

(2008) Hideharu Hashimoto et al.   NATURE

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism

(2008) Kyohei Arita et al.   NATURE

Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1

(2008) George V. Avvakumov et al.   NATURE

SRA-Domain Proteins Required for DRM2-Mediated De Novo DNA Methylation

(2008) Lianna M. Johnson et al.   PLoS Genetics