Dynamic interaction of SARAF with STIM1 and Orai1 to modulate store-operated calcium entry

Store-operated Ca2+Entry-associated Regulatory factor (SARAF) Plays an Important Role in the Regulation of Arachidonate-regulated Ca2+(ARC) Channels

(2016) Letizia Albarran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol modulates Orai1 channel function

(2016) Isabella Derler et al.   Science Signaling

Cholesterol modulates Orai1 channel function

(2016) Isabella Derler et al.   Science Signaling

Homer proteins mediate the interaction between STIM1 and Cav1.2 channels

(2015) Natalia Dionisio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

TRPC6 participates in the regulation of cytosolic basal calcium concentration in murine resting platelets

(2014) Letizia Albarran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Complex role of STIM1 in the activation of store-independent Orai1/3 channels

(2014) Xuexin Zhang et al.   JOURNAL OF GENERAL PHYSIOLOGY

Translocation between PI(4,5)P2-poor and PI(4,5)P2-rich microdomains during store depletion determines STIM1 conformation and Orai1 gating

(2014) Jozsef Maléth et al.   Nature Communications

Transient receptor potential ankyrin-1 (TRPA1) modulates store-operated Ca 2+ entry by regulation of STIM1-Orai1 association

(2013) Letizia Albarrán et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function

(2013) Archana Jha et al.   JOURNAL OF CELL BIOLOGY

Native STIM2 and ORAI1 proteins form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons

(2013) Joanna Gruszczynska-Biegala et al.   JOURNAL OF NEUROCHEMISTRY

TRPC1 and Orai1 interact with STIM1 and mediate capacitative Ca2+ entry caused by acute hypoxia in mouse pulmonary arterial smooth muscle cells

(2012) Lih Chyuan Ng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

FKBP52 is involved in the regulation of SOCE channels in the human platelets and MEG 01 cells

(2012) Esther López et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

SARAF Inactivates the Store Operated Calcium Entry Machinery to Prevent Excess Calcium Refilling

(2012) Raz Palty et al.   CELL

Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1

(2012) B. Pani et al.   JOURNAL OF CELL SCIENCE

Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)

(2012) X. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation

(2011) Martin Muik et al.   EMBO JOURNAL

Role of lipid rafts in the interaction between hTRPC1, Orai1 and STIM1

(2010) Isaac Jardin et al.   Channels

TRPC channels as STIM1-regulated SOCs

(2010) Joseph P. Yuan et al.   Channels

A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

(2009) Takumi Kawasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

(2009) Martin Muik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Ca2+Release-activated Ca2+(CRAC) Modulatory Domain (CMD) within STIM1 Mediates Fast Ca2+-dependent Inactivation of ORAI1 Channels

(2009) Isabella Derler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRPC3 Regulates Agonist-stimulated Ca2+Mobilization by Mediating the Interaction between Type I Inositol 1,4,5-Trisphosphate Receptor, RACK1, and Orai1

(2009) Geoffrey E. Woodard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

(2009) Joseph P. Yuan et al.   NATURE CELL BIOLOGY

Structural and Mechanistic Insights into STIM1-Mediated Initiation of Store-Operated Calcium Entry

(2008) Peter B. Stathopulos et al.   CELL

Novel Role for STIM1 as a Trigger for Calcium Influx Factor Production

(2008) Peter Csutora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Orai1 Mediates the Interaction between STIM1 and hTRPC1 and Regulates the Mode of Activation of hTRPC1-forming Ca2+Channels

(2008) Isaac Jardin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Requirement for Orai1 in Store-operated TRPC1-STIM1 Channels

(2008) Kwong Tai Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STIM1 Gates TRPC Channels, but Not Orai1, by Electrostatic Interaction

(2008) Weizhong Zeng et al.   MOLECULAR CELL