Article
Obstetrics & Gynecology
Audrey M. Marsidi, Lauren M. Kipling, Jennifer F. Kawwass, Akanksha Mehta
Summary: The study found that paternal age has an impact on the likelihood of pregnancy and live birth among couples undergoing assisted reproductive technology, especially in women aged 35 and older. Compared to paternal age under 45, paternal age over 46 is associated with lower success rates in IVF cycles.
FERTILITY AND STERILITY
(2021)
Article
Medicine, Research & Experimental
Sweta Ravisankar, Alison Y. Ting, Melinda J. Murphy, Nash Redmayne, Dorothy Wang, Carrie A. McArthur, Diana L. Takahashi, Paul Kievit, Shawn L. Chavez, Jon D. Hennebold
Summary: This study found that short-term consumption of a Western-style high-fat diet led to weight gain and increased body fat in female rhesus macaques. It also showed an increase in inflammatory response in the follicular fluid, which had a negative impact on preimplantation development.
Review
Medicine, General & Internal
Frank Mayta-Tovalino, Carlos Diaz-Arocutipa, Alejandro Piscoya, Adrian V. V. Hernandez
Summary: In overweight or obese patients, receiving probiotics treatment led to improvements in BMI, weight, and low-density lipoprotein levels compared to the control group. However, probiotics had no significant effect on blood pressure, glucose, high-density lipoprotein, or triglycerides.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Megan Rodgers, Alexandra L. Migdal, Tahereh Ghorbani Rodriguez, Zsu-Zsu Chen, Anjali K. Nath, Robert E. Gerszten, Natasha Kasid, Elena Toschi, Juliet Tripaldi, Brent Heineman, Minh Phan, Long Ngo, Eleftheria Maratos-Flier, Jody Dushay
Summary: In this study, long-term weight loss with exenatide treatment was similar to that achieved with a hypocaloric diet in a population of early high responders. Weight loss at 3 months of treatment predicted super responder status in both treatment groups, with individual variability observed in weight loss outcomes.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Multidisciplinary Sciences
Jie Tang, Xinhong Zhu, Yanbing Chen, Dongming Huang, Henning Tiemeier, Ruoling Chen, Wei Bao, Qingguo Zhao
Summary: This study found that in the Chinese population, maternal pre-pregnancy BMI was significantly associated with the risk of adverse pregnancy outcomes, and this risk varied according to maternal age. Further research is needed to explore whether and how counseling and interventions for women with either low or high BMI before pregnancy can reduce the risk of adverse pregnancy outcomes.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Simon Birk Kjor Jensen, Charlotte Janus, Julie Rehne Lundgren, Christian Rimer Juhl, Rasmus Michael Sandsdal, Lisa Moller Olsen, Anne Andresen, Signe Amalie Borg, Ida Christine Jacobsen, Graham Finlayson, Bente Merete Stallknecht, Jens Juul Holst, Sten Madsbad, Signe Sorensen Torekov
Summary: This study explored the effects of exercise and liraglutide single or combination treatment on eating and sedentary behavior after weight loss. The results showed that liraglutide prevented the decrease in appetite suppression score and maintained weight loss. Exercise did not increase appetite or sedentary behavior, despite increased exercise energy expenditure and maintained weight loss. The combination of exercise and liraglutide increased conscious food intake restriction and decreased sedentary time, facilitating additional weight loss.
NATURE COMMUNICATIONS
(2022)
Article
Sport Sciences
Pablo B. Pedrianes-Martin, Mario Perez-Valera, David Morales-Alamo, Marcos Martin-Rincon, Ismael Perez-Suarez, Jose A. Serrano-Sanchez, Juan Jose Gonzalez-Henriquez, Victor Galvan-Alvarez, Carmen Acosta, David Curtelin, Pedro de Pablos-Velasco, Jose A. L. Calbet
Summary: The study found that hypertensive patients have a higher resting metabolic rate than normotensive patients, along with reduced insulin sensitivity. This increased metabolic rate can be explained by an elevated myocardial oxygen consumption due to an increased resting double product, combined with differences in body composition between hypertensive and normotensive subjects.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Endocrinology & Metabolism
Meng Rao, Zexing Yang, Cunmei Su, Zihan Zhao, Ruixue Wan, Jiang Liu, Youlin Yao, Zhenfang Su, Kunhua Wang, Li Tang, Shuhua Zhao
Summary: Paternal subclinical hypothyroidism is associated with worse clinical outcomes after in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI), especially in men aged 35 and above. Further prospective studies and basic research are needed to confirm these results and understand the underlying mechanisms.
Review
Nutrition & Dietetics
Yupeng Liu, Yi Liu, Yufeng Huang, Siyu Le, Huinan Jiang, Binye Ruan, Xuemei Ao, Xudong Shi, Xiaoyi Fu, Shuran Wang
Summary: This study aimed to summarize earlier data on the association between osteoporosis and obesity (general and central) and compare their impacts on osteoporosis. The findings indicated that general overweight and obesity were associated with lower odds of developing osteoporosis, while underweight was associated with higher odds. However, central obesity did not show a significant association with osteoporosis.
CLINICAL NUTRITION
(2023)
Article
Obstetrics & Gynecology
Nahid Punjani, Pietro Bortoletto, Phillip A. Romanski, James Kashanian, Steven Spandorfer
Summary: This study aimed to investigate the impact of advancing paternal age on fresh embryo transfer cycle outcomes. The study found that increasing paternal age did not show any statistically significant differences in implantation, clinical intrauterine pregnancy, pregnancy loss, or live birth.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Nutrition & Dietetics
Yan Zou, Lichun Huang, Dong Zhao, Mengjie He, Dan Han, Danting Su, Ronghua Zhang
Summary: Children and adolescents with overweight/obesity have a higher intake of carbohydrates, especially from the food group of cereals, tubers, and beans. Snacks play a significant role in the high intake of the food group of cereals, tubers, and beans among children and adolescents with overweight/obesity.
Article
Endocrinology & Metabolism
Jin Yu, Yulai Zhou, Jie Ding, Danying Zhang, Chaoqin Yu, Hefeng Huang
Summary: This study aimed to investigate the metabolic characteristics of overweight women with PCOS and analyze the possible mechanisms. The results showed that overweight PCOS patients were prone to hypertension, diabetes, low gonadal levels, and insulin resistance. Inflammatory cytokines CXCL12/SDF-1, Serpin E1/PAI-1, and MIF were predicted to play a crucial role in inducing insulin resistance in overweight PCOS through various biological functions and signal transductions.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Oncology
Jonas Busk Holm, Ann H. Rosendahl, Signe Borgquist
Summary: Breast cancer is the second most common cancer in women worldwide, with the risk influenced by factors such as age, heredity, reproductive factors, physical inactivity, and obesity. Obesity not only increases the risk of breast cancer but also worsens outcomes for patients.Awareness of the association between obesity and breast cancer is crucial due to the increasing global obesity rate.
Article
Endocrinology & Metabolism
Yingying Lin, Zhiwei Chen, Qinfang Qian, Yanxia Wang, Xiaoyan Xiu, Ping Ou, Jiaoning Fang, Guobo Li
Summary: This study investigated whether paternal BMI before pregnancy is a risk factor for maternal-neonatal outcomes and long-term prognosis in offspring. The results showed that paternal overweight and obesity were associated with higher incidences of hypertensive disorder complicating pregnancy, cesarean delivery, excessive gestational weight gain, and macrosomia. Additionally, paternal obesity also increased the incidence of asthma, hand-foot-and-mouth disease, anemia, dental caries, and obesity in adolescents. Therefore, paternal obesity is a risk factor for adverse maternal-neonatal outcomes and poor long-term prognosis in adolescents.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Endocrinology & Metabolism
Zoe L. Reichental, Victoria M. O'Brien, Sharleen L. O'Reilly
Summary: This review evaluates breastfeeding interventions for at-risk populations, finding that such interventions can improve exclusive early postpartum breastfeeding and any breastfeeding at 6 months in women with gestational diabetes or obesity/overweight. Further randomized controlled trials are needed to confirm efficacy and harmonize breastfeeding outcome reporting.
