Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading

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Title
Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading
Authors
Keywords
checkpoint kinase inhibitors, cancer treatment, replication stress, DNA damage, CDK activity
Journal
Oncotarget
Volume 8, Issue 7, Pages -
Publisher
Impact Journals, LLC
Online
2016-12-28
DOI
10.18632/oncotarget.14089

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