Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation

Published 2016 View Full Article

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Title
Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation
Authors
Keywords
cisplatin, arginine-starvation, DEC1-HIF-1α-c-Myc axis, ASS1, DNA methylation
Journal
Oncotarget
Volume 7, Issue 50, Pages -
Publisher
Impact Journals, LLC
Online
2016-09-29
DOI
10.18632/oncotarget.12308

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