Article
Oncology
Pengfei Li, Yutian Lai, Long Tian, Qinghua Zhou
Summary: This meta-analysis study found that lower PNI was associated with decreased overall survival and progression-free survival in advanced cancer patients, and had adverse effects on objective response rate.
Review
Oncology
Kuo-Chuan Hung, Cheuk-Kwan Sun, Yang-Pei Chang, Jheng-Yan Wu, Po-Yu Huang, Ting-Hui Liu, Chien-Hung Lin, Wan-Jung Cheng, I-Wen Chen
Summary: This article is a systematic review and meta-analysis studying the association between Prognostic Nutritional Index (PNI) and prognosis in glioma patients. The study found that a high PNI was associated with better overall survival and progression-free survival in glioma patients, and this finding remained consistent even after sensitivity analysis. These findings have important implications in the treatment of glioma patients.
FRONTIERS IN ONCOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Mei-Yu Chen, Jiang-Xiong Wen, Mei-Ting Lu, Xiang-Yu Jian, Xiao-Liang Wan, Zhi-Wen Xu, Jian-Qiu Liang, Jian-Di Wu
Summary: PNI can serve as a predictive factor for the prognosis of heart failure patients. Lower PNI is significantly associated with higher all-cause mortality and adverse cardiac event risk.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Oncology
Min Tang, Zhongxiong Jia, Ju Zhang
Summary: Our meta-analysis included 8 eligible studies with a total of 3631 patients. The results showed that a low PNI level was significantly associated with shorter OS, PFS, and DMFS. Additionally, female patients, higher tumor stage, lower ALT level, and lower WBC level were associated with a lower PNI level.
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY
(2021)
Article
Oncology
Changqing Mao, Weixin Xu, Weina Ma, Chun Wang, Zhaojiao Guo, Jun Yan
Summary: The meta-analysis revealed that low PNI is associated with shorter survival outcomes in patients with renal cell carcinoma, indicating that PNI could be used as an effective prognostic indicator in RCC.
FRONTIERS IN ONCOLOGY
(2021)
Review
Oncology
Baibei Li, Huachu Deng, Ziyan Zhou, Bo Tang
Summary: This study found that a high Fibrinogen to pre-albumin ratio (FPR) is significantly associated with poor overall survival, recurrence-free survival, progression-free survival, complications, disease-free survival, and cancer-specific survival in malignant digestive system tumors. Despite intergroup differences, FPR is strongly associated with overall and relapse-free survival, and sensitivity analysis suggests the stability of the results.
CANCER CELL INTERNATIONAL
(2022)
Review
Nutrition & Dietetics
Liwei Ni, Jing Huang, Jiyuan Ding, Junyan Kou, Tingting Shao, Jun Li, Liujie Gao, Wanzhen Zheng, Zhen Wu
Summary: This study investigated the association between pretreatment prognostic nutritional index (PNI) and clinical survival outcomes for advanced-stage cancer patients treated with immune checkpoint inhibitors (ICIs). The results showed that a higher level of PNI was associated with a greater objective response rate and favorable disease control rate, while low PNI was linked to shorter overall survival and unfavorable progressive-free survival.
FRONTIERS IN NUTRITION
(2022)
Review
Medicine, General & Internal
Rongqiang Liu, Shiyang Zheng, Cui Yan Yang, Yajie Yu, Shengjia Peng, Qianmin Ge, Qi Lin, Qiuyu Li, Wenqing Shi, Yi Shao
Summary: In digestive system cancers, high AKR1B10 expression is not associated with overall survival and disease-free survival, but indicates poor overall survival in oral squamous cell carcinoma and favorable disease-specific survival in hepatocellular carcinoma.
Article
Pathology
Lu Guo, Ying Tang, Yukai Wang, Hong Xu
Summary: High NEAT1 expression in digestive system tumors is significantly associated with poor overall survival, lymphatic metastasis, distal metastasis, and advanced tumor stage. However, high NEAT1 expression is not related to patient age, gender, tumor size, and tumor differentiation.
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
(2021)
Review
Oncology
Dan Cao, Zongxin Zhang
Summary: This meta-analysis found that a lower level of geriatric nutritional risk index (GNRI) is associated with poorer prognosis in patients with diffuse large B-cell lymphoma (DLBCL), as well as clinical factors of disease progression.
FRONTIERS IN ONCOLOGY
(2023)
Review
Oncology
Tao Yu, Xin Gao, Zicheng Zheng, Xinyu Zhao, Shiyao Zhang, Chunqiang Li, Gang Liu
Summary: The study shows that high ITH is associated with worse prognosis in many solid tumors, although this association is not present for some cancers. ITH is expected to be a promising clinical prognostic factor for improving assessment, treatment, and surveillance strategies.
FRONTIERS IN ONCOLOGY
(2021)
Review
Oncology
Jie Peng, Xiaoyu Li, Mingsheng Huang, Mincai Ma, Qin Huang, Ning Huang, Yuan Cheng
Summary: This meta-analysis evaluated the prognostic value of PNI and CONUT scores in patients with glioblastoma. The results showed that a high PNI score was associated with longer overall survival and progression-free survival, while a low CONUT score was associated with longer overall survival. Multivariate analyses confirmed that high PNI score and low CONUT score were independently associated with longer overall survival. Therefore, PNI and CONUT scores have prognostic value in patients with glioblastoma, but further large-scale studies are needed to confirm these findings.
FRONTIERS IN ONCOLOGY
(2023)
Article
Cell Biology
Menglu Dai, Qijun Sun
Summary: This meta-analysis found that low pretreatment prognostic nutritional index (PNI) was associated with inferior disease-free survival (DFS) and overall survival (OS) among oral carcinoma patients, but not with cancer-specific survival (CSS). Significant correlations of low PNI were found with TNM stages III-IV and age >= 65 years in oral carcinoma patients. Therefore, PNI could be a promising and effective index for predicting prognosis in patients with oral cancer.
Review
Oncology
Bi-Xia Liu, Chao-Tao Tang, Xi-Jian Dai, Ling Zeng, Fei Cheng, Youxiang Chen, Chunyan Zeng
Summary: S100P overexpression is associated with poor overall survival in patients with digestive system cancers, particularly as a prognostic indicator in non-gastrointestinal tract cancers.
FRONTIERS IN ONCOLOGY
(2021)
Article
Medicine, General & Internal
Yongquan Tang, Jiayu Liang, Zhihong Liu, Ruochen Zhang, Zijun Zou, Kan Wu, Yiping Lu, Xin Wei
Summary: The study found that the level of PNI in renal cell carcinoma patients is closely related to overall survival and recurrence-free survival. Low PNI significantly affects the prognosis of patients.
Article
Oncology
Shi Yao, Shan-Shan Dong, Jing-Miao Ding, Yu Rong, Yu-Jie Zhang, Hao Chen, Jia-Bin Chen, Yi-Xiao Chen, Han Yan, Zhijun Dai, Yan Guo
GENES CHROMOSOMES & CANCER
(2020)
Article
Oncology
Linghui Zhou, Yang Zhao, Yi Zheng, Meng Wang, Tian Tian, Shuai Lin, Qian Hao, Peng Xu, Yujiao Deng, Na Li, Ying Wu, Tielin Yang, Huafeng Kang, Zhijun Dai
ANNALS OF SURGICAL ONCOLOGY
(2020)
Article
Oncology
Zhen Zhai, Yi Zheng, Na Li, Yujiao Deng, Linghui Zhou, Tian Tian, Si Yang, Qian Hao, Dingli Song, Ying Wu, Dai Zhang, Zhijun Dai, Ziming Wang
Article
Nanoscience & Nanotechnology
Peng Xu, Jia Yao, Zhen Li, Meng Wang, Linghui Zhou, Guansheng Zhong, Yi Zheng, Na Li, Zhen Zhai, Si Yang, Ying Wu, Dai Zhang, Zhijun Dai
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2020)
Article
Immunology
Lijuan Lyu, Yi Zheng, Yun Hong, Meng Wang, Yujiao Deng, Ying Wu, Peng Xu, Si Yang, Shuqian Wang, Jia Yao, Dai Zhang, Yan Guo, Jun Lyu, Zhijun Dai
INTERNATIONAL IMMUNOPHARMACOLOGY
(2020)
Article
Oncology
Hongtao Li, Linghui Zhou, Jing Ma, Yuyao Zhu, Jingjing Fan, Na Li, Yi Zheng, Tong Sha, Zhen Zhai, Binlin Ma, Zhijun Dai
Article
Medicine, General & Internal
Dai Zhang, Si Yang, Yiche Li, Jia Yao, Jian Ruan, Yi Zheng, Yujiao Deng, Na Li, Bajin Wei, Ying Wu, Zhen Zhai, Jun Lyu, Zhijun Dai
Article
Multidisciplinary Sciences
Kang Liu, Gaobo Huang, Pengkang Chang, Wei Zhang, Tao Li, Zhijun Dai, Yi Lv
SCIENTIFIC REPORTS
(2020)
Article
Medicine, Research & Experimental
Si Yang, Yi Zheng, Linghui Zhou, Jing Jin, Yujiao Deng, Jia Yao, Pengtao Yang, Li Yao, Ying Wu, Zhen Zhai, Na Li, Lijuan Lyu, Zhijun Dai
MOLECULAR THERAPY-NUCLEIC ACIDS
(2020)
Article
Oncology
Lijuan Lyu, Meng Wang, Yi Zheng, Tian Tian, Yujiao Deng, Peng Xu, Shuai Lin, Si Yang, Linghui Zhou, Qian Hao, Ying Wu, Zhijun Dai, Huafeng Kang
CANCER MANAGEMENT AND RESEARCH
(2020)
Article
Medicine, General & Internal
Zhen Zhai, Yi Zheng, Jia Yao, Yu Liu, Jian Ruan, Yujiao Deng, Linghui Zhou, Peng Zhao, Si Yang, Jingjing Hu, Bajin We, Ying Wu, Dai Zhang, Huafeng Kang, Zhijun Dai
Article
Biotechnology & Applied Microbiology
Si Yang, Shuai Lin, Kang Liu, Yuanxing Liu, Peng Xu, Yi Zheng, Yujiao Deng, Dai Zhang, Zhen Zhai, Na Li, Xueting Ren, Zhijun Dai, Huafeng Kang
Summary: Through bioinformatics methods, we identified eight differentially expressed, immune-related, and prognostic RBPs to construct a risk signature that effectively distinguished high- and low-risk patients, with its predictive capacity validated in the International Cancer Genomics Consortium (ICGC) cohort. We speculated that the high-risk group was more sensitive to targeted therapy.
Article
Integrative & Complementary Medicine
Shuai Lin, Qianwen Sheng, Xiaobin Ma, Shanli Li, Peng Xu, Cong Dai, Meng Wang, Huafeng Kang, Zhijun Dai
Summary: Marsdenia tenacissima (MTE) has been found to inhibit proliferation, induce autophagy, apoptosis, and S phase cell cycle arrest in hepatocellular carcinoma (HCC) cells.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2022)
Article
Engineering, Biomedical
Hongwei Lu, Ji Xu, Jinfan Yang, Zhongling Wang, Peng Xu, Qian Hao, Wen Luo, Shuaijun Li, Zhengqing Li, Xiangdong Xue, Hongbo Zheng, Zhangjian Zhou, Hao Wu, Xiaobin Ma, Yuanpei Li
Summary: This study presents a smart on-demand targeting nanotheranostic system that improves drug delivery efficiency for ovarian cancer through stimuli-responsive releasing.
Article
Oncology
Ying Wu, Yujiao Deng, Zhijun Dai, Yubo Ma, Lijuan Lyu, Chen Lei, Yi Zheng, Yizhen Li, Ziming Wang, Jie Gao
Summary: Based on the Global Burden of Disease Study 2019, high fasting plasma glucose (FPG) has been identified as a risk factor for bladder cancer globally. The death and DALY rates of bladder cancer attributable to high FPG have significantly increased since 1990, particularly among older males.
