Serine 707 of APPL1 is Critical for the Synaptic NMDA Receptor-Mediated Akt Phosphorylation Signaling Pathway

A novel phosphorylation site of N-methyl- d -aspartate receptor GluN2B at S1284 is regulated by Cdk5 in neuronal ischemia

(2015) Wen Lu et al.   EXPERIMENTAL NEUROLOGY

Phosphorylation of Tyrosine 1070 at the GluN2B Subunit Is Regulated by Synaptic Activity and Critical for Surface Expression ofN-Methyl-d-aspartate (NMDA) Receptors

(2015) Wen Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of NMDAR2B in an inflammatory model of Alzheimer's disease: Modulation by NOS inhibitors

(2014) Ahmed Maher et al.   BRAIN RESEARCH BULLETIN

Mechanisms of NOS1AP action on NMDA receptor-nNOS signaling

(2014) Michael J. Courtney et al.   Frontiers in Cellular Neuroscience

The nNOS-p38MAPK Pathway Is Mediated by NOS1AP during Neuronal Death

(2013) L.-L. Li et al.   JOURNAL OF NEUROSCIENCE

Cysteine residues 87 and 320 in the amino terminal domain of NMDA receptor GluN2A govern its homodimerization but do not influence GluN2A/GluN1 heteromeric assembly

(2013) Xiao-Min Zhang et al.   Neuroscience Bulletin

Adaptor Protein APPL1 Couples Synaptic NMDA Receptor with Neuronal Prosurvival Phosphatidylinositol 3-Kinase/Akt Pathway

(2012) Y.-b. Wang et al.   JOURNAL OF NEUROSCIENCE

Dysregulated Src upregulation of NMDA receptor activity: a common link in chronic pain and schizophrenia

(2011) Michael W. Salter et al.   FEBS Journal

An APPL1/Akt signaling complex regulates dendritic spine and synapse formation in hippocampal neurons

(2011) Devi Majumdar et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The PSD-95/nNOS complex: New drugs for depression?

(2011) Marika V. Doucet et al.   PHARMACOLOGY & THERAPEUTICS

Identification of Phosphorylation Sites within the Signaling Adaptor APPL1 by Mass Spectrometry

(2010) Randi L. Gant-Branum et al.   JOURNAL OF PROTEOME RESEARCH

Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95

(2010) Li Zhou et al.   NATURE MEDICINE

APPL1: role in adiponectin signaling and beyond

(2008) Sathyaseelan S. Deepa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Endosomal Protein Appl1 Mediates Akt Substrate Specificity and Cell Survival in Vertebrate Development

(2008) Annette Schenck et al.   CELL