Structural basis for tRNA modification by Elp3 from Dehalococcoides mccartyi

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes

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Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA

(2016) E. L. Schwalm et al.   SCIENCE

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity

(2015) Danny D. Nedialkova et al.   CELL

Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator-dependent tRNA modification

(2015) Olga Kolaj-Robin et al.   FEBS Journal

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Correlation Map, a goodness-of-fit test for one-dimensional X-ray scattering spectra

(2015) Daniel Franke et al.   NATURE METHODS

Dimerization of elongator protein 1 is essential for Elongator complex assembly

(2015) Huisha Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Elp2 Subunit Is Essential for Elongator Complex Assembly and Functional Regulation

(2015) Chunming Dong et al.   STRUCTURE

Structure of the Kti11/Kti13 Heterodimer and Its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2

(2015) Sebastian Glatt et al.   STRUCTURE

Recent Advances in Radical SAM Enzymology: New Structures and Mechanisms

(2014) Jiarui Wang et al.   ACS Chemical Biology

Familial dysautonomia (FD) patients have reduced levels of the modified wobble nucleoside mcm5s2U in tRNA

(2014) Tony Karlsborn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of a Cross-Linked Protein–Nucleic Acid Substrate Radical in the Reaction Catalyzed by RlmN

(2014) Alexey Silakov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dph3 Is an Electron Donor for Dph1-Dph2 in the First Step of Eukaryotic Diphthamide Biosynthesis

(2014) Min Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Archaeal Elp3 catalyzes tRNA wobble uridine modification at C5 via a radical mechanism

(2014) Kiruthika Selvadurai et al.   Nature Chemical Biology

Structural insights into Elongator function

(2013) Sebastian Glatt et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Analysis of differences in oxygen sensitivity of Fe–S clusters

(2013) Marta K. Bruska et al.   DALTON TRANSACTIONS

tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding

(2013) V. A. N. Rezgui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimization of protein purification and characterization using Thermofluor screens

(2013) Stephane Boivin et al.   PROTEIN EXPRESSION AND PURIFICATION

Dehalococcoides mccartyi gen. nov., sp. nov., obligately organohalide-respiring anaerobic bacteria relevant to halogen cycling and bioremediation, belong to a novel bacterial class, Dehalococcoidia classis nov., order Dehalococcoidales ord. nov. and family Dehalococcoidaceae fam. nov., within the phylum Chloroflexi

(2012) F. E. Loffler et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

New developments in theATSASprogram package for small-angle scattering data analysis

(2012) Maxim V. Petoukhov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Crystal Structure of Elongator Subcomplex Elp4–6

(2012) Zhijie Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase

(2012) Sebastian Glatt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evolutionary conservation of codon optimality reveals hidden signatures of cotranslational folding

(2012) Sebastian Pechmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy

(2012) A. Benitez-Paez et al.   RNA

Role of Elongator Subunit Elp3 in Drosophila melanogaster Larval Development and Immunity

(2011) J. Walker et al.   GENETICS

Human tRNALys3UUU Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto–Enol Tautomerism

(2011) Franck A.P. Vendeix et al.   JOURNAL OF MOLECULAR BIOLOGY

The quantitative proteome of a human cell line

(2011) M. Beck et al.   Molecular Systems Biology

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

(2011) Hossein Najmabadi et al.   NATURE

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family Member Bruchpilot

(2011) Katarzyna Miśkiewicz et al.   NEURON

Unexpected Accumulation of ncm5U and ncm5s2U in a trm9 Mutant Suggests an Additional Step in the Synthesis of mcm5U and mcm5s2U

(2011) Changchun Chen et al.   PLoS One

Structural Basis for Methyl Transfer by a Radical SAM Enzyme

(2011) A. K. Boal et al.   SCIENCE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

How the Sequence of a Gene Can Tune Its Translation

(2010) Kurt Fredrick et al.   CELL

Elongator function in tRNA wobble uridine modification is conserved between yeast and plants

(2010) Constance Mehlgarten et al.   MOLECULAR MICROBIOLOGY

Elongator, a conserved multitasking complex?

(2010) Wim Versées et al.   MOLECULAR MICROBIOLOGY

A role for the elongator complex in zygotic paternal genome demethylation

(2010) Yuki Okada et al.   NATURE

RNA metabolism and the pathogenesis of motor neuron diseases

(2010) Robin Lemmens et al.   TRENDS IN NEUROSCIENCES

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Defects in tRNA Modification Associated with Neurological and Developmental Dysfunctions in Caenorhabditis elegans Elongator Mutants

(2009) Changchun Chen et al.   PLoS Genetics

Variants of the elongator protein 3 ( ELP3 ) gene are associated with motor neuron degeneration

(2008) Claire L. Simpson et al.   HUMAN MOLECULAR GENETICS

An Iron-Sulfur Cluster Domain in Elp3 Important for the Structural Integrity of Elongator

(2008) Catherine Greenwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Mouse Ikbkap, a Subunit of Elongator, Leads to Transcriptional Deficits and Embryonic Lethality That Can Be Rescued by Human IKBKAP

(2008) Y.-T. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

A pause for thought along the co-translational folding pathway

(2008) Anton A. Komar   TRENDS IN BIOCHEMICAL SCIENCES