Mechanistic relationship between the vagal afferent pathway, central nervous system and peripheral organs in appetite regulation

Peripheral oxytocin activates vagal afferent neurons to suppress feeding in normal and leptin-resistant mice: a route for ameliorating hyperphagia and obesity

(2015) Yusaku Iwasaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

One-day high-fat diet induces inflammation in the nodose ganglion and hypothalamus of mice

(2015) T. M. Zaved Waise et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RM-493, a Melanocortin-4 Receptor (MC4R) Agonist, Increases Resting Energy Expenditure in Obese Individuals

(2015) Kong Y. Chen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diet-induced obesity causes peripheral and central ghrelin resistance by promoting inflammation

(2015) Farhana Naznin et al.   JOURNAL OF ENDOCRINOLOGY

Glucagon-Like Peptide 1 Interacts with Ghrelin and Leptin to Regulate Glucose Metabolism and Food Intake through Vagal Afferent Neuron Signaling

(2015) Charlotte C Ronveaux et al.   JOURNAL OF NUTRITION

G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons

(2015) Masoud Ghamari-Langroudi et al.   NATURE

Oxytocin reduces caloric intake in men

(2015) Elizabeth A. Lawson et al.   Obesity

Effect of Reversible Intermittent Intra-abdominal Vagal Nerve Blockade on Morbid Obesity

(2014) Sayeed Ikramuddin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Central PACAP mediates the sympathetic effects of leptin in a tissue-specific manner

(2013) M. Tanida et al.   NEUROSCIENCE

Gastric distension activates NUCB2/nesfatin-1-expressing neurons in the nucleus of the solitary tract

(2013) Marion S. Bonnet et al.   REGULATORY PEPTIDES

Gastric Expression of Plasminogen Activator Inhibitor (PAI)-1 Is Associated with Hyperphagia and Obesity in Mice

(2012) Susan Kenny et al.   ENDOCRINOLOGY

Deconstruction of a neural circuit for hunger

(2012) Deniz Atasoy et al.   NATURE

Neuroendocrine control of feeding behavior and psychomotor activity by pituitary adenylate cyclase-activating polypeptide (PACAP) in vertebrates

(2012) Kouhei Matsuda et al.   Obesity Research & Clinical Practice

Diet-induced obesity leads to the development of leptin resistance in vagal afferent neurons

(2011) Guillaume de Lartigue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Stimulation of the hypothalamic ventromedial nuclei by pituitary adenylate cyclase-activating polypeptide induces hypophagia and thermogenesis

(2011) Jon M. Resch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

A One-Year Randomized Trial of Lorcaserin for Weight Loss in Obese and Overweight Adults: The BLOSSOM Trial

(2011) Meredith C. Fidler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diet-induced adaptation of vagal afferent function

(2011) Stephen Kentish et al.   JOURNAL OF PHYSIOLOGY-LONDON

Eating rate during a fixed-portion meal does not affect postprandial appetite and gut peptides or energy intake during a subsequent meal

(2011) J. Philip Karl et al.   PHYSIOLOGY & BEHAVIOR

Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus

(2011) K. W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EGR1Is a Target for Cooperative Interactions between Cholecystokinin and Leptin, and Inhibition by Ghrelin, in Vagal Afferent Neurons

(2010) Guillaume de Lartigue et al.   ENDOCRINOLOGY

Lorcaserin, A 5-HT2CReceptor Agonist, Reduces Body Weight by Decreasing Energy Intake without Influencing Energy Expenditure

(2010) Corby K. Martin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Multicenter, Placebo-Controlled Trial of Lorcaserin for Weight Management

(2010) Steven R. Smith et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nesfatin-1 evokes Ca2+ signaling in isolated vagal afferent neurons via Ca2+ influx through N-type channels

(2009) Yusaku Iwasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of GABAergic Signaling by AgRP Neurons to the Parabrachial Nucleus Leads to Starvation

(2009) Qi Wu et al.   CELL

Nesfatin-1-Regulated Oxytocinergic Signaling in the Paraventricular Nucleus Causes Anorexia through a Leptin-Independent Melanocortin Pathway

(2009) Yuko Maejima et al.   Cell Metabolism

Peripheral Administration of Nesfatin-1 Reduces Food Intake in Mice: The Leptin-Independent Mechanism

(2009) H. Shimizu et al.   ENDOCRINOLOGY

Melanin-concentrating hormone 1-receptor antagonist suppresses body weight gain correlated with high receptor occupancy levels in diet-induced obesity mice

(2009) Masahiko Ito et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

PACAP Neurons in the Hypothalamic Ventromedial Nucleus Are Targets of Central Leptin Signaling

(2009) Z. Hawke et al.   JOURNAL OF NEUROSCIENCE

Gut Microbiota and Its Possible Relationship With Obesity

(2009) John K. DiBaise et al.   MAYO CLINIC PROCEEDINGS

A new anorexigenic protein, nesfatin-1

(2009) Hiroyuki Shimizu et al.   PEPTIDES

CCK-8S activates c-Fos in a dose-dependent manner in nesfatin-1 immunoreactive neurons in the paraventricular nucleus of the hypothalamus and in the nucleus of the solitary tract of the brainstem

(2009) Steffen Noetzel et al.   REGULATORY PEPTIDES

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

(2008) Qingchun Tong et al.   NATURE NEUROSCIENCE

Vagal and hormonal gut-brain communication: from satiation to satisfaction

(2008) H.-r. Berthoud   NEUROGASTROENTEROLOGY AND MOTILITY

Pituitary Adenylate Cyclase-Activating Polypeptide Inhibits Food Intake in Mice Through Activation of the Hypothalamic Melanocortin System

(2008) Lourdes Mounien et al.   NEUROPSYCHOPHARMACOLOGY

Intra-abdominal vagal blocking (VBLOC therapy): Clinical results with a new implantable medical device

(2008) M. Camilleri et al.   SURGERY

Discovery and Structure−Activity Relationship of (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a Selective Serotonin 5-HT2CReceptor Agonist for the Treatment of Obesity

(2007) Brian M. Smith et al.   JOURNAL OF MEDICINAL CHEMISTRY