Cognitive Reserve and the Prevention of Dementia: the Role of Physical and Cognitive Activities

The effect of physical activity on cognitive function in patients with dementia: A meta-analysis of randomized control trials

(2016) C. Groot et al.   AGEING RESEARCH REVIEWS

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

(2016) Bruno Dubois et al.   Alzheimers & Dementia

Prefrontal activation may predict working-memory training gain in normal aging and mild cognitive impairment

(2016) Anouk Vermeij et al.   Brain Imaging and Behavior

The long-term association between physical activity and risk of dementia in the community: the Hisayama Study

(2016) Hiro Kishimoto et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Physical activity over a decade modifies age-related decline in perfusion, gray matter volume, and functional connectivity of the posterior default-mode network—A multimodal approach

(2016) Carl-Johan Boraxbekk et al.   NEUROIMAGE

Neural correlates of training and transfer effects in working memory in older adults

(2016) Stephan Heinzel et al.   NEUROIMAGE

Relationships of peripheral IGF-1, VEGF and BDNF levels to exercise-related changes in memory, hippocampal perfusion and volumes in older adults

(2016) Anne Maass et al.   NEUROIMAGE

A systematic review of MRI studies examining the relationship between physical fitness and activity and the white matter of the ageing brain

(2016) Claire E. Sexton et al.   NEUROIMAGE

Exercise-induced neuroplasticity in human Parkinson's disease: What is the evidence telling us?

(2016) Mark A. Hirsch et al.   PARKINSONISM & RELATED DISORDERS

Independent and combined effects of cognitive and physical activity on incident MCI

(2015) Tiffany F. Hughes et al.   Alzheimers & Dementia

Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia

(2015) Anna-Maija Tolppanen et al.   Alzheimers & Dementia

A Life-Course Study of Cognitive Reserve in Dementia—From Childhood to Old Age

(2015) Serhiy Dekhtyar et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Occupational Complexity and Cognitive Reserve in a Middle-Aged Cohort at Risk for Alzheimer's Disease

(2015) Elizabeth A. Boots et al.   ARCHIVES OF CLINICAL NEUROPSYCHOLOGY

Effects of home-based bench step exercise on inflammatory cytokines and lipid profiles in elderly Japanese females: A randomized controlled trial

(2015) Yuichiro Nishida et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Lifelong bilingualism and neural reserve against Alzheimer's disease: A review of findings and potential mechanisms

(2015) Brian T. Gold   BEHAVIOURAL BRAIN RESEARCH

Social activity, cognitive decline and dementia risk: a 20-year prospective cohort study

(2015) Riccardo E. Marioni et al.   BMC PUBLIC HEALTH

Age of dementia diagnosis in community dwelling bilingual and monolingual Hispanic Americans

(2015) Deborah M. Lawton et al.   CORTEX

A bidirectional relationship between physical activity and executive function in older adults

(2015) Michael Daly et al.   Frontiers in Human Neuroscience

Relationship of medial temporal lobe atrophy, APOE genotype, and cognitive reserve in preclinical Alzheimer's disease

(2015) Anja Soldan et al.   HUMAN BRAIN MAPPING

Physical Activity and Amyloid-βBrain Levels in Elderly Adults with Intact Cognition and Mild Cognitive Impairment

(2015) Philipe de Souto Barreto et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Intensity and Types of Physical Exercise in Relation to Dementia Risk Reduction in Community-Living Older Adults

(2015) Allen T.C. Lee et al.   Journal of the American Medical Directors Association

Physical Activity as Protective Factor against Dementia: A Prospective Population-Based Study (NEDICES)

(2015) Sara Llamas-Velasco et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

(2015) Tiia Ngandu et al.   LANCET

Physical activity, body mass index, and brain atrophy in Alzheimer's disease

(2015) Christina P. Boyle et al.   NEUROBIOLOGY OF AGING

Cognitive activity relates to cognitive performance but not to Alzheimer disease biomarkers

(2015) Christopher M. Gidicsin et al.   NEUROLOGY

Efficacy of a Community-Based Physical Activity Program KM2H2 for Stroke and Heart Attack Prevention among Senior Hypertensive Patients: A Cluster Randomized Controlled Phase-II Trial

(2015) Jie Gong et al.   PLoS One

Supervised exercise training reduces oxidative stress and cardiometabolic risk in adults with type 2 diabetes: a randomized controlled trial

(2015) Giovanni Vinetti et al.   Scientific Reports

A meta-analysis of prospective studies on the role of physical activity and the prevention of Alzheimer’s disease in older adults

(2015) Michael W Beckett et al.   BMC Geriatrics

Effect of Cognitive Reserve on Age-Related Changes in Cerebrospinal Fluid Biomarkers of Alzheimer Disease

(2015) Rodrigo P. Almeida et al.   JAMA Neurology

Would Older Adults with Mild Cognitive Impairment Adhere to and Benefit from a Structured Lifestyle Activity Intervention to Enhance Cognition?: A Cluster Randomized Controlled Trial

(2015) Linda Chiu-wa Lam et al.   PLoS One

The effects of multimodal exercise on cognitive and physical functioning and brain-derived neurotrophic factor in older women: a randomised controlled trial

(2014) Sue Vaughan et al.   AGE AND AGEING

Is Bilingualism Associated With a Lower Risk of Dementia in Community-living Older Adults? Cross-sectional and Prospective Analyses

(2014) Caleb M. Yeung et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Aerobic exercise increases hippocampal volume in older women with probable mild cognitive impairment: a 6-month randomised controlled trial

(2014) Lisanne F ten Brinke et al.   BRITISH JOURNAL OF SPORTS MEDICINE

Disruption of Resting Functional Connectivity in Alzheimer’s Patients and At-Risk Subjects

(2014) Lenka Krajcovicova et al.   Current Neurology and Neuroscience Reports

Can leisure activities slow dementia progression in nursing home residents? A cluster-randomized controlled trial

(2014) Sheung-Tak Cheng et al.   INTERNATIONAL PSYCHOGERIATRICS

Working Memory Load-Dependent Brain Response Predicts Behavioral Training Gains in Older Adults

(2014) S. Heinzel et al.   JOURNAL OF NEUROSCIENCE

Gene-Environment Interactions: Lifetime Cognitive Activity, APOE Genotype, and Beta-Amyloid Burden

(2014) M. Wirth et al.   JOURNAL OF NEUROSCIENCE

Concurrent and Longitudinal Relationships Between Cognitive Activity, Cognitive Performance, and Brain Volume in Older Adult Women

(2014) L. Vaughan et al.   JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES

Potential for primary prevention of Alzheimer's disease: an analysis of population-based data

(2014) Sam Norton et al.   LANCET NEUROLOGY

Vascular hippocampal plasticity after aerobic exercise in older adults

(2014) A Maass et al.   MOLECULAR PSYCHIATRY

Physical activity, fitness, and gray matter volume

(2014) Kirk I. Erickson et al.   NEUROBIOLOGY OF AGING

Physical Activity, Weight Status, Diabetes and Dementia: A 34-Year Follow-Up of the Population Study of Women in Gothenburg

(2014) Kirsten Mehlig et al.   NEUROEPIDEMIOLOGY

Computerized Cognitive Training in Cognitively Healthy Older Adults: A Systematic Review and Meta-Analysis of Effect Modifiers

(2014) Amit Lampit et al.   PLOS MEDICINE

Effect of Diet or Diet Plus Physical Activity Versus Usual Care on Inflammatory Markers in Patients with Newly Diagnosed Type 2 Diabetes: The Early ACTivity In Diabetes (ACTID) Randomized, Controlled Trial

(2014) Dylan Thompson et al.   Journal of the American Heart Association

Four weeks of combination exercise training improved executive functions, episodic memory, and processing speed in healthy elderly people: evidence from a randomized controlled trial

(2013) Rui Nouchi et al.   AGE

Physical Activity and Risk of Cognitive Impairment Among Oldest-Old Women

(2013) Sophia Wang et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Mental and Physical Activities Delay Cognitive Decline in Older Persons with Dementia

(2013) Sheung-Tak Cheng et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Imaging markers of structural and functional brain changes that precede cognitive symptoms in risk for Alzheimer’s disease

(2013) Alison Burggren et al.   Brain Imaging and Behavior

Normal Cognitive Aging

(2013) Caroline N. Harada et al.   CLINICS IN GERIATRIC MEDICINE

Light physical activity determined by a motion sensor decreases insulin resistance, improves lipid homeostasis and reduces visceral fat in high-risk subjects: PreDiabEx study RCT

(2013) K-H Herzig et al.   INTERNATIONAL JOURNAL OF OBESITY

Leisure Activity in Old Age and Risk of Dementia: A 15-Year Prospective Study

(2013) D. Eriksson Sorman et al.   JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Adult neurogenesis in the mammalian hippocampus: Why the dentate gyrus?

(2013) L. J. Drew et al.   LEARNING & MEMORY

Video game training enhances cognitive control in older adults

(2013) J. A. Anguera et al.   NATURE

Bilingualism delays age at onset of dementia, independent of education and immigration status

(2013) S. Alladi et al.   NEUROLOGY

Cognitive function affects trainability for physical performance in exercise intervention among older adults with mild cognitive impairment

(2013) Kazuki Uemura et al.   Clinical Interventions in Aging

Leisure Activities Alleviate Depressive Symptoms in Nursing Home Residents With Very Mild or Mild Dementia

(2012) Sheung-Tak Cheng et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Association of Lifetime Cognitive Engagement and Low β-Amyloid Deposition

(2012) Shawn M. Marks   ARCHIVES OF NEUROLOGY

Maintaining long-term adherence to lifestyle interventions for cognitive health in late life

(2012) Linda Chiu Wa Lam et al.   INTERNATIONAL PSYCHOGERIATRICS

A 1-Year Randomized Controlled Trial Comparing Mind Body Exercise (Tai Chi) With Stretching and Toning Exercise on Cognitive Function in Older Chinese Adults at Risk of Cognitive Decline

(2012) Linda C.W. Lam et al.   Journal of the American Medical Directors Association

Cognitive reserve in ageing and Alzheimer's disease

(2012) Yaakov Stern   LANCET NEUROLOGY

Physical activity and amyloid-β plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing

(2012) B M Brown et al.   MOLECULAR PSYCHIATRY

Brain development and aging: Overlapping and unique patterns of change

(2012) Christian K. Tamnes et al.   NEUROIMAGE

Total daily physical activity and the risk of AD and cognitive decline in older adults

(2012) A.S. Buchman et al.   NEUROLOGY

Spatial navigation training protects the hippocampus against age-related changes during early and late adulthood

(2011) Martin Lövdén et al.   NEUROBIOLOGY OF AGING

The Aging Hippocampus

(2011) Kirk I. Erickson et al.   NEUROSCIENTIST

Exercise training increases size of hippocampus and improves memory

(2011) K. I. Erickson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exercise and Alzheimer's disease biomarkers in cognitively normal older adults

(2010) Kelvin Y. Liang et al.   ANNALS OF NEUROLOGY

Television viewing time independently predicts all-cause and cardiovascular mortality: the EPIC Norfolk Study

(2010) Katrien Wijndaele et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Examining the association between late-life leisure activity participation and global cognitive decline in community-dwelling elderly Chinese in Hong Kong

(2010) Grace Tak Yu Leung et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Human Neuroscience and the Aging Mind: A New Look at Old Problems

(2010) P. A. Reuter-Lorenz et al.   JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES

Cognitive activity and the cognitive morbidity of Alzheimer disease

(2010) R. S. Wilson et al.   NEUROLOGY

Aerobic Exercise and Neurocognitive Performance: A Meta-Analytic Review of Randomized Controlled Trials

(2010) Patrick J. Smith et al.   PSYCHOSOMATIC MEDICINE

Cognitive Exercise and Its Role in Cognitive Function in Older Adults

(2010) Nicola Gates et al.   Current Psychiatry Reports

Physical activity and memory functions: An interventional study

(2009) R. Ruscheweyh et al.   NEUROBIOLOGY OF AGING

Cognitive activities delay onset of memory decline in persons who develop dementia

(2009) C. B. Hall et al.   NEUROLOGY

Leisure activities and the risk of dementia in the elderly: Results from the Three-City Study

(2009) T. N. Akbaraly et al.   NEUROLOGY

Aging of cerebral white matter: a review of MRI findings

(2008) Faith M. Gunning-Dixon et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Lifespan Mental Activity Predicts Diminished Rate of Hippocampal Atrophy

(2008) Michael J. Valenzuela et al.   PLoS One

Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence

(2008) M. Hamer et al.   PSYCHOLOGICAL MEDICINE