Spitting out the demons: Extracellular vesicles in glioblastoma

Optimizing preservation of extracellular vesicular miRNAs derived from clinical cerebrospinal fluid

(2016) Johnny C. Akers et al.   Cancer Biomarkers

Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity

(2016) F. Ricklefs et al.   CANCER RESEARCH

Extracellular vesicles and intercellular communication within the nervous system

(2016) Valentina Zappulli et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular vesicles round off communication in the nervous system

(2016) Vivian Budnik et al.   NATURE REVIEWS NEUROSCIENCE

SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions

(2016) F. Pucci et al.   SCIENCE

From glioblastoma to endothelial cells through extracellular vesicles: messages for angiogenesis

(2016) Ilaria Giusti et al.   TUMOR BIOLOGY

TrkB-containing exosomes promote the transfer of glioblastoma aggressiveness to YKL-40-inactivated glioblastoma cells

(2016) Sandra Pinet et al.   Oncotarget

Comparative Analysis of Technologies for Quantifying Extracellular Vesicles (EVs) in Clinical Cerebrospinal Fluids (CSF)

(2016) Johnny C. Akers et al.   PLoS One

Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells

(2015) Jeroen de Vrij et al.   INTERNATIONAL JOURNAL OF CANCER

miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients

(2015) Johnny C. Akers et al.   JOURNAL OF NEURO-ONCOLOGY

Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice

(2015) Masaki Morishita et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Circulating biomarkers for gliomas

(2015) Manfred Westphal et al.   Nature Reviews Neurology

Serum exosomes and cytokines promote a T-helper cell type 2 environment in the peripheral blood of glioblastoma patients

(2015) Larry A. Harshyne et al.   NEURO-ONCOLOGY

Glioma-derived extracellular vesicles selectively suppress immune responses

(2015) Justin E. Hellwinkel et al.   NEURO-ONCOLOGY

Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain

(2015) Kristan E. van der Vos et al.   NEURO-ONCOLOGY

Extracellular vesicle-transported Semaphorin3A promotes vascular permeability in glioblastoma

(2015) L Treps et al.   ONCOGENE

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

(2015) Tianzhi Yang et al.   PHARMACEUTICAL RESEARCH

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

(2015) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma

(2015) Huilin Shao et al.   Nature Communications

Exosomes isolated from plasma of glioma patients enrolled in a vaccination trial reflect antitumor immune activity and might predict survival

(2015) Laurent Muller et al.   OncoImmunology

Nanofilaments on glioblastoma exosomes revealed by peak force microscopy

(2014) S. Sharma et al.   Journal of the Royal Society Interface

Exosomes as a Nanodelivery System: a Key to the Future of Neuromedicine?

(2014) Arian Aryani et al.   MOLECULAR NEUROBIOLOGY

Belonging to a network—microRNAs, extracellular vesicles, and the glioblastoma microenvironment

(2014) Jakub Godlewski et al.   NEURO-ONCOLOGY

Molecular lipidomics of exosomes released by PC-3 prostate cancer cells

(2013) Alicia Llorente et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1

(2013) A. Bronisz et al.   CANCER RESEARCH

Rab27 GTPases Distribute Extracellular Nanomaps for Invasive Growth and Metastasis: Implications for Prognosis and Treatment

(2013) An Hendrix et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1

(2013) Katrin J. Svensson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Heparin blocks transfer of extracellular vesicles between donor and recipient cells

(2013) Nadia A. Atai et al.   JOURNAL OF NEURO-ONCOLOGY

miR-21 in the Extracellular Vesicles (EVs) of Cerebrospinal Fluid (CSF): A Platform for Glioblastoma Biomarker Development

(2013) Johnny C. Akers et al.   PLoS One

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

(2013) H. C. Christianson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

(2013) P. Kucharzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells

(2013) Cheryl CY Li et al.   RNA Biology

Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

(2013) Jessian L Munoz et al.   Molecular Therapy-Nucleic Acids

BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles

(2013) Walter W Chen et al.   Molecular Therapy-Nucleic Acids

RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls

(2012) Mikkel Noerholm et al.   BMC CANCER

Neuroimaging

(2012) Jennifer L. Clarke et al.   CANCER JOURNAL

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway

(2012) Guanglei Zhuang et al.   EMBO JOURNAL

Identification and proteomic profiling of exosomes in human cerebrospinal fluid

(2012) Jonathan M Street et al.   Journal of Translational Medicine

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

(2012) Shin-ichiro Ohno et al.   MOLECULAR THERAPY

Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy

(2012) Huilin Shao et al.   NATURE MEDICINE

Thromboembolic disease in patients with high-grade glioma

(2012) J. R. Perry   NEURO-ONCOLOGY

Inhibition of Glioma Cell Lysosome Exocytosis Inhibits Glioma Invasion

(2012) Yu Liu et al.   PLoS One

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

ExoCarta 2012: database of exosomal proteins, RNA and lipids

(2011) S. Mathivanan et al.   NUCLEIC ACIDS RESEARCH

Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

(2011) Leonora Balaj et al.   Nature Communications

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Prothrombotic state in glioblastoma multiforme: an evaluation of the procoagulant activity of circulating microparticles

(2010) Maria Teresa Sartori et al.   JOURNAL OF NEURO-ONCOLOGY

Astrocytes and Glioblastoma cells release exosomes carrying mtDNA

(2009) Michele Guescini et al.   JOURNAL OF NEURAL TRANSMISSION

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Proteomic and immunologic analyses of brain tumor exosomes

(2008) Michael W. Graner et al.   FASEB JOURNAL

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE

Response criteria for glioma

(2008) A Gregory Sorensen et al.   Nature clinical practice. Oncology